Gene Information

Name : nrdE (stu1270)
Accession : YP_139717.1
Strain : Streptococcus thermophilus LMG 18311
Genome accession: NC_006448
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1121648 - 1123807 bp
Length : 2160 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCTTTAAAAAATCTTGGCGATGTTTCTTACTTCCGCCTCAACAACGAAATTAACCGTCCTGTAAACGGTCAGATTCC
TTTGCATAAGGATAAAGAAGCGCTTCGTGCCTTTTTCCTTGAAAATGTTAAGCCAAATTCAATGGCATTCAACAGCATCA
CAGATAAAATTAATTATTTGATTGAAAACGACTATATTGAGTCTGAATTCATCGGTAAATATGAACCTGCTTTCATCGAA
AAATTGTCTGCAGAAATTCATGCTCAAAAATTCCGCTTTCAATCTTTCATGGCAGCCTACAAGTTCTACCAACAATATGC
TCTCAAAACAAACGATGGCGAGACATACCTTGAAAGTTTTGAAGATCGTGTTCTTTTTAATGCTCTTTACTTCGCTGATG
GTGATGAAAACCTGGCTAGTGACCTTGCTAACGAAATGATTCACCAACGTTATCAACCTGCTACTCCTTCATTTTTAAAT
GCTGGACGTAGTCGTCGTGGAGAACTCGTTTCATGTTTCCTTATCCAAGTAACGGACGATATGAATTCCATCGGTCGTTC
TATTAACTCAGCTCTCCAATTATCACGTATTGGTGGAGGGGTTGGTATTAGCCTATCTAACCTACGTGAAGCTGGTGCTC
CTATCAAGGGATATGCTGGTGCTGCTTCTGGAGTTGTCCCAGTTATGAAGCTTTTTGAAGACAGCTTCTCTTACTCAAAT
CAACTTGGTCAACGTCAAGGTGCTGGTGTTGTTTATCTGGATGTTTTCCACCCAGATATCCTTGCCTTCCTTTCAACTAA
GAAAGAGAACGCTGATGAAAAGGTACGTGTTAAGACATTGTCACTAGGTGTTACAGTACCAGATAAATTCTACGAGTTAG
CACGTAATAATGAAGATATGTATCTCTTCAGCCCCTACTCTATCGAAAAAGAATACGGTAAACCATATAACTACATTGAT
ATTACAGCTATGTATGATGAATTGGTTGCCAATCCTAATATCACCAAAACTAAGATTAATGCGCGTGAGTTAGAAACTGA
AATTTCTAAACTCCAACAAGAATCTGGTTACCCATATATCATCAACATTGATACAGCTAACAGACATAACCCAATTGATG
GTAAAATTGTTATGTCCAACCTCTGTTCTGAGATTCTCCAAGTTCAAACACCAAGTGAACTTAACGATTCTCAAGAATTT
GTTAAACTCGGTACAGATATCTCATGTAACCTTGGATCTACTAATATCCTGAACATGATGACTTCACCTGACTTTGGTCG
TTCCATTAAGACTATGACACGTGCGCTTACCTTTGTTACAGACAGCTCAAGTATCGATGCCGTTCCATCAATCAAAAATG
GGAACCAACAAGCTCATACCTTTGGTTTAGGAGCTATGGGGCTTCACTCTTACCTTGCTAAACACCATATCGAGTATGGT
AGCCCAGAATCTATTGAATTCACTAATATCTACTTCATGCTTATGAACTACTGGACTTTAGTTGAATCTAACAATATCGC
CCGTGAACGTCAAGAAACCTTTGTCGGCTTTGAGAATTCAAAATATGCTGACGGTTCTTACTTTGATAAATACGTTACAG
GGCAATACGTTCCTAAATCTGACCGTGTTAAAGAACTTTTCGAAGGCCACTTCATCCCACAAGCCAAGGATTGGGAGGAA
CTACGTGAACTCGTTAAAAAAGATGGTCTCTACCATCAAAACCGTTTGGCTGTTGCGCCAAATGGCTCAATCTCTTACAT
TAACGACTGTTCTGCTTCTATTCATCCAATCACACAACGTATTGAAGAACGTCAAGAGAAGAAAATCGGAAAAATTTACT
ATCCAGCCAACGGTCTTTCAACAGACACTATTCCTTTCTACACTTCAGCCTACGACATGGACATGCGTAAAGTTATCGAC
GTTTATGCCGCTGCGACTGAACACGTTGATCAAGGTTTGTCATTAACCCTATTCTTGCGTAGTGAGTTGCCTAAAGAAAT
TTACGAATGGAAAACAGAAAATAAACTAACAACTCGCGATCTTTCTATCCTTCGTAACTACGCCTTTAACAAAGGAATCA
AGTCAATCTACTACATCCGTACTTACACAGATGACGGCGAAGAAGTTGGCTCTAACCAGTGTGAAAGCTGTGTCATCTAA

Protein sequence :
MSLKNLGDVSYFRLNNEINRPVNGQIPLHKDKEALRAFFLENVKPNSMAFNSITDKINYLIENDYIESEFIGKYEPAFIE
KLSAEIHAQKFRFQSFMAAYKFYQQYALKTNDGETYLESFEDRVLFNALYFADGDENLASDLANEMIHQRYQPATPSFLN
AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLDVFHPDILAFLSTKKENADEKVRVKTLSLGVTVPDKFYELARNNEDMYLFSPYSIEKEYGKPYNYID
ITAMYDELVANPNITKTKINARELETEISKLQQESGYPYIINIDTANRHNPIDGKIVMSNLCSEILQVQTPSELNDSQEF
VKLGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIDAVPSIKNGNQQAHTFGLGAMGLHSYLAKHHIEYG
SPESIEFTNIYFMLMNYWTLVESNNIARERQETFVGFENSKYADGSYFDKYVTGQYVPKSDRVKELFEGHFIPQAKDWEE
LRELVKKDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTIPFYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFLRSELPKEIYEWKTENKLTTRDLSILRNYAFNKGIKSIYYIRTYTDDGEEVGSNQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 53