Gene Information

Name : ureA (pNG7125)
Accession : YP_134542.1
Strain :
Genome accession: NC_006395
Putative virulence/resistance : Virulence
Product : urease subunit gamma
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0831
EC number : 3.5.1.5
Position : 123171 - 123557 bp
Length : 387 bp
Strand : +
Note : UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter

DNA sequence :
ATGAAACTCACAGCCAAAGAACAGGAACGACTCACGGTCTTTACCGCCGCAGAGGTCGCGCGGCGCCGCAAGGAACGCGG
TGTCCCGCTGAACCACCCCGAAGCCGTCGCTTACATCAGCGACTGGTGCATCGAACGCGGTCGTGACGGCCAGTCGGTCG
CCGAAATCCGGTCCGGTGCGTCGAAACTGCTCGGCCGAGAGGACGTGATGGACGGCGTGCCGGAGATGATAGACATGATT
CAGGTCGAACCGGTGTTCCCCGACGGAACCAAACTGGTCACGGTTCACGACCCGATTCGGTCCGACAGTGTTGGGTCCGC
TGACGACGAAACGACGGAGTCAGAGGCGGCGACCGATGGCGGGGACTCGGCGGGGACAGACGAATGA

Protein sequence :
MKLTAKEQERLTVFTAAEVARRRKERGVPLNHPEAVAYISDWCIERGRDGQSVAEIRSGASKLLGREDVMDGVPEMIDMI
QVEPVFPDGTKLVTVHDPIRSDSVGSADDETTESEAATDGGDSAGTDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureA YP_005682176.1 urease subunit gamma Not tested PiCp 7 Protein 4e-26 61
ureA YP_005684268.1 urease subunit gamma Not tested PiCp 7 Protein 4e-26 61
ureA YP_003784327.1 urease subunit gamma Not tested PiCp 7 Protein 4e-26 61
ureA YP_005686360.1 urease subunit gamma Not tested PiCp 7 Protein 4e-26 61
ureA NP_286678.1 urease subunit gamma Virulence TAI Protein 1e-18 56
ureA NP_287086.1 urease subunit gamma Not tested TAI Protein 1e-18 56