Gene Information

Name : murD (PBPRA3217)
Accession : YP_131325.1
Strain :
Genome accession: NC_006370
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 3654898 - 3656241 bp
Length : 1344 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAATGGCTTAGGCGGTGTAAAAAAGGTTGTTGTCATTGGTTTAGGGATGACAGGCCTGTCGGTTGTTAATTTCTGGCT
ACGTCAAACTGGCGATCGTGATATCAAAGTGATTGATACCCGCGCAACACCGCCTGGGCAAGATAAACTCCCTTCTAGCG
TTGAGCTATGTGCAGGGCAGTGGAATATGAATTGGCTGTTAGAGGCTGATTTGATTGTTGCGAGTCCAGGCATTGCGCTG
GCAACTCCTGAACTAGTTGCTGCTAAAGCCGCAGGTATTGAAATCGTCGGTGATATTGAGCTATTTGCCCGTGTTGTGAC
AAAGCCTGTTGTGGCGATCACAGGCTCTAATGGCAAGAGTACGGTGACGAGCCTGATTGGTGAAATGGCAAAAGAAGCCG
GTATCAATGTTGGCGTTGGTGGCAACATCGGCTTTGCAGCGTTAGATATGTTAGTGAACGAGCATGATTTGTATGTGCTT
GAGCTATCCAGTTTTCAACTTGAAACGACCTCATCGTTACAGTTAAAAGCTGCCGTATACCTTAATCTTTCTGAAGATCA
CATGGATCGCTATAACGGGCTAGAAGATTATAGCTTGGCAAAGATGCGGATCTTTGAACATGCCGAATTAGCGGTATATA
ACCGCGATGATCTGGCTACTTTTCCTGTCAGCTTCAGCCATCAAATCACCAGCTTTGGCTTTGATAACCAAGATTATGGT
TTGGTGACGTTACACGGAGAAGAGTTTTTAGCCCTAGACGAACAACCGATCATGAAGACAAGTGATATTGCATTGGTTGG
TCGACATAATGTTGCGAATAGTTTGGCGGCATTAGCCTTGGCAGATGCGGTCAACATCGATCGTCAAGCGGTATGCCGAG
CTTTGCAGCGTTATAACGGTTTAGCGCATCGCTGTCAGTTAGTGGTAAATCAACATGATGTAAAATGGGTGAATGATTCA
AAAGCAACGAATCTAGCCAGTACGTTAGCCGCGCTTAAAGGATTAAACTTACCGGGCAAGTTGCATTTGCTGGTGGGTGG
TGATGGGAAAGGGGCTGATTTTTCGGAACTAAAGCTTGTTTTGGCTGACTTAAATGTACAACTTTACTGTTTTGGCCGTG
ATGGAAACCAGTTTATGCCGCTGGTTGATGCGCCTATTTGTATTGAGACAATGGCTCAAGCAATGGCAATAGCTGCAGAT
ACCGCGCAAAAAGGCGACATGATCTTATTGTCACCAGCATGTGCTAGCTTTGACCAATTTCCCAACTTTATGGCACGAGG
TGATGCATTTATTGAACAAGCTAAAGCCTTACAACCTCGTGTTGCAGGAGCAAAGGCATGTTAA

Protein sequence :
MNGLGGVKKVVVIGLGMTGLSVVNFWLRQTGDRDIKVIDTRATPPGQDKLPSSVELCAGQWNMNWLLEADLIVASPGIAL
ATPELVAAKAAGIEIVGDIELFARVVTKPVVAITGSNGKSTVTSLIGEMAKEAGINVGVGGNIGFAALDMLVNEHDLYVL
ELSSFQLETTSSLQLKAAVYLNLSEDHMDRYNGLEDYSLAKMRIFEHAELAVYNRDDLATFPVSFSHQITSFGFDNQDYG
LVTLHGEEFLALDEQPIMKTSDIALVGRHNVANSLAALALADAVNIDRQAVCRALQRYNGLAHRCQLVVNQHDVKWVNDS
KATNLASTLAALKGLNLPGKLHLLVGGDGKGADFSELKLVLADLNVQLYCFGRDGNQFMPLVDAPICIETMAQAMAIAAD
TAQKGDMILLSPACASFDQFPNFMARGDAFIEQAKALQPRVAGAKAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-55 44
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-55 44