Gene Information

Name : PBPRA2284 (PBPRA2284)
Accession : YP_130472.1
Strain :
Genome accession: NC_006370
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 2629739 - 2630617 bp
Length : 879 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGAAAACGTGTTTAGCGGTCGATATTGGCGGTACTAAGATTGCCGCGGCGTTGGTTAAAGACAATGTTATCGTTACACG
TGTTCAAATTTCGACACCCACTTCAAAAGAGGCGAGTGCATTAACCGTAGCGTTAACAGATTTATTAACTCCCCTTGCCC
TAGAAGCAGATCATGTTGCTGTTGCATCGACAGGTATTATTAATCACGGAGTATTAACAGCATTAAACCCAGATAACCTT
GGTGGCTTAAATCATTTCCCTCTACACCAAGTAATTAGTGAAATAACCCAGTTACCTGTTGTTGTTATTAATGATGCACA
AGCTGCAGCTTGGTTTGAATATAAAGCACTTAATCAAGCCGTGTCTGATATGGCATTTATTACCGTATCAACTGGCGTTG
GGGCGGGTTTTGTGCAGAAAGAAATACTCAATACCGGTACTAGAGGTATTGCGGGCCATGCTGGACACATGTTGGCAGAT
CCGAACGGACCTATATGTGGCTGCGGCCGTAAAGGTTGTGTAGAAAGCATTGCATCTGGTACCGCAATTGGCATCGCTGG
ACAGTCTTTCTTTGGTACTGATTGCGATGGTGAAACCGTTTATCAGCACCTACTTACTGGCGATAAAAACGCGATTGCCA
TTGTTGATCGCTCTGCCAGTACGATTGCAAACCTGATTGCTGATCTTACTATCTCACTTGACCTTGATATCGTTGTATTA
GGGGGTAGTGTTGGGCTTGCTTCTGGATATTTAGCAAGGGTTAGAACTTACCTTGAACGGTTACCCAATGTATATGTTCC
TGACGTAATTGCTGCAAGTTCTGGCGCTGATGCTGGCCTGCTTGGTGTTGCGTTATGGGCAGAGCAAAACATTAAATAA

Protein sequence : 
MKTCLAVDIGGTKIAAALVKDNVIVTRVQISTPTSKEASALTVALTDLLTPLALEADHVAVASTGIINHGVLTALNPDNL
GGLNHFPLHQVISEITQLPVVVINDAQAAAWFEYKALNQAVSDMAFITVSTGVGAGFVQKEILNTGTRGIAGHAGHMLAD
PNGPICGCGRKGCVESIASGTAIGIAGQSFFGTDCDGETVYQHLLTGDKNAIAIVDRSASTIANLIADLTISLDLDIVVL
GGSVGLASGYLARVRTYLERLPNVYVPDVIAASSGADAGLLGVALWAEQNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 5e-43 51
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 7e-37 43
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 7e-37 43
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 2e-36 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PBPRA2284 YP_130472.1 N-acetylmannosamine kinase VFG1115 Protein 3e-37 43