Gene Information

Name : serS (lpl0551)
Accession : YP_125917.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 599320 - 600600 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATAATCAATTACTTAGAGAGAATCCTCAATATGTAGCAACCCAATTGCTGAAGCGAGGATTTCAATTTGATGC
GGTCACTTTCAGTCAGTTGGAAGAAAAGCGTAAGGCTTTGCAAGTAAGTACGCAATCATTACAGAACGAACGAAATTTGC
GTTCGAAAGCCATCGGTGAAGCAAAATCTCGCGGTGAAAACATAGAACCTATGCGCGAAGAAGTGAATAAACTTGGCGCT
AAACTGGAGCAACAAAAGACTGAACTGGATGAGATTCTTAAGCAAATTGAGGTAATTAGCCTATCATTACCTAATATTCC
TCATGAATCAGTACCTGTTGGTAAAGATGAATTGGATAATCAGGAAATCAGAAAATGGGGCGACGTACCTGCTTTTTCTT
TCCCTGTAAAGTCACATGATGAATTGGGTGAAGCACTAGGGCAAATGGATTTTGCGCTTGCAGCTAAAATTACGGGCAGT
CGTTTTGTCGTCATGAAAGGGCATCTGGCCCGATTACATCGGGCTTTAATTCAATTCATGCTGGATATACATATTCAGCA
ACATGGTTACCAGGAAATATATGTACCTTATATTGTTAATGCGGATAGCTTATTAGGGACTGGACAGTTACCAAAGTTTG
AGGCTGATTTATTTAAATTAACAGGAGATAATGGGTACTACTTGACGTCTACTTCAGAAATTCCAGTGACCAATACAGTA
AGGGAAATGATATTGTCTGCTGAGCAATTACCTATTCGTTATGTTTGCCATTCCCCATGTTTTCGTAGTGAGGCAGGTTC
TTACGGTAAAGACACAAAGGGAATGATTAGACAGCATCAATTTGAGAAAGTTGAACTGGTCTGGATTACCAAACCGGAAG
ATTCTTATAATGCTCTAGAGCAACTTACTCAGCATGCTGAAGTTATTTTACAGCGTTTGAAATTGCCTTACCGAGTGGTC
GCTTTGTGTACCGGGGATATAGGCGCCGGTTCAGCCAAAACCTATGATCTTGAGGTTTGGTTGCCTAGCCAGAATACTTA
TCGAGAAATATCCTCTTGTTCCAATATGGAGGCATTTCAGGCACGCCGAATGAAAGCGCGTTTCCGCAATCCGGATACTA
ATGAGATTCAATTAGTCCACACTCTAAATGGATCAGGTTTAGCTGTTGGAAGAACTTTAGTTGCCATTATGGAGAATTAT
CAAGATGAGCATGGAAACATTCATATACCGGATGCTTTGAAGCCTTATTTAGGTGGTATTGATATCATCTCTGTGAAATA
G

Protein sequence :
MLDNQLLRENPQYVATQLLKRGFQFDAVTFSQLEEKRKALQVSTQSLQNERNLRSKAIGEAKSRGENIEPMREEVNKLGA
KLEQQKTELDEILKQIEVISLSLPNIPHESVPVGKDELDNQEIRKWGDVPAFSFPVKSHDELGEALGQMDFALAAKITGS
RFVVMKGHLARLHRALIQFMLDIHIQQHGYQEIYVPYIVNADSLLGTGQLPKFEADLFKLTGDNGYYLTSTSEIPVTNTV
REMILSAEQLPIRYVCHSPCFRSEAGSYGKDTKGMIRQHQFEKVELVWITKPEDSYNALEQLTQHAEVILQRLKLPYRVV
ALCTGDIGAGSAKTYDLEVWLPSQNTYREISSCSNMEAFQARRMKARFRNPDTNEIQLVHTLNGSGLAVGRTLVAIMENY
QDEHGNIHIPDALKPYLGGIDIISVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-100 51