Gene Information

Name : hemC (lpl2660)
Accession : YP_127988.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 3031149 - 3032078 bp
Length : 930 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAGCGCAAAAATTATACGAATCGCAACGAGGCAGAGCCCGCTCGCACTATGGCAGGCTAATCATGTACGGGAAATGCT
TGTAAAGCAATGGCCAAATCTAAGCATTGAATTATTACCCATGATAACCTCCGGCGATCGATTTCTTAAAGATAAATTAT
TATCCGCAGGAGGGAAAGGGTTATTTGTTAAAGAGTTAGAAGAAGCATTATTAGATAAAAGAGCGGACTTGGCTGTTCAT
TCGACCAAAGACATGCCAGCACAACTTCCGGATGGTCTCTCGTTGGCCGCCATTTGCAAAAGAGATAACCCTTTTGACGC
TTTAATAAGTCCCCAATTTAAGAGTCTGGATGCTCTCCCCAAAAACGCAATTATTGGTACATCGAGTCTTAGACGTCAAT
CGCAACTATTGGCTTACAATCCCAATTTGCAAGTCAAAACATTAAGAGGAAACATCCATACAAGACTCAGCAAACTGGAG
TCAGGAGAGTATCAAGCCATTATTCTTGCTGCCGCAGGCTTGGAAAGAATGGGCTTGGCACATCACATCACCCAACTCAT
ACCCGATGACATTATGCTGCCTACTTGTGCTCAGGGCGCTTTATGTATTGAGTGCCGAACTGACGATTTGGAAATCCAAG
AGCTGATTTATGGCTTAAATGATCCAATTTCTGCTCTTTGTGTTCATACCGAGCGGCGCGTCAACGCAAAATTAGGAGGC
AATTGCCACATACCCTTTGCTGTTTATTGTACCATTACTGCGGAGAACCTCCTCCTTTTGAGAGCAAAAGTACTTAATCT
GGATGGTTCTCAAATGATTGATGATGAGCAACAAGGGAAAATAGAAGAAGCTGAAATTATTGCAGACAGGTGTACCGAGT
CATTAATGACAAAAGGTGCGATGACCTTACTGAGCACGATACCATCATGA

Protein sequence : 
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVH
STKDMPAQLPDGLSLAAICKRDNPFDALISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQVKTLRGNIHTRLSKLE
SGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIYGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITAENLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIADRCTESLMTKGAMTLLSTIPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-66 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-66 49