Gene Information

Name : kdsB (lpl1883)
Accession : YP_127221.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2109088 - 2109840 bp
Length : 753 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGCCATAATTTTCATGTAATTATACCAGCCAGATATCACTCCAGTCGTTTTCCAGGTAAATTACTTCAAGAAATTAA
CGGCATTACCGTGATTGAACGAGTTTACAGGCAAGCACTTCTGGCAGAACCAATGTCGGTGATTATTGCCACTGATCATG
ATGAGATAGCTGACCGTGCAATCCAATTTGGAGCGGAGGTTGTAATCACTTCACATACGCACCAAACTGGAACTGATCGA
ATTGCAGAGGTTGTCGCCAAGGGTAGCTTTGCTCCTGATGACGTCATTGTCAATGTGCAAGGTGATGAGCCATTTATCCG
ACCCCAATTAATTCAACAAGTTGCTTGCTCTTTAACAAAGACAAAGGCGCCTGTGTCTACTTTATGCTGGCCTATTAGCA
GCCTTCAAATATTAAATAACCCTAATGTGGTTAAAGTGGTACGCACTCGAGATAATCACGCTCTTTATTTTTCAAGAAGC
GCGATACCTTTTCACAGAGATGATAAAAACGCTTATTCCAATACCTTCAGGCATATCGGTTTATATGCTTATCGTGCTGC
CTTTTTACTGGAATTCGTTAGCTGGCCGCCCTGTACCTTGGAACAAATAGAGTGTTTGGAGCAATTGCGCATCCTATGGT
CAGGTTTCTCTATCCGGGTTGAGGAGGCCTGCGAAGAACCTTTACAGGATATTAATACAAAAGAAGATTTGATTTTGGCT
CAGCAATATTTTCTTGATACTTTCAATGTATAA

Protein sequence :
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPMSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVVAKGSFAPDDVIVNVQGDEPFIRPQLIQQVACSLTKTKAPVSTLCWPISSLQILNNPNVVKVVRTRDNHALYFSRS
AIPFHRDDKNAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVEEACEEPLQDINTKEDLILA
QQYFLDTFNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-35 41
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-35 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-35 41