Gene Information

Name : fliP (lpl1753)
Accession : YP_127091.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 1957456 - 1958205 bp
Length : 750 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :
ATGAAAATTAAAAGTTGGTTACTGATTTTTATATTACTTCTTTTATTACCCGTTGCAGGTCACACAGACCCTTTATCCTT
TCCTGTTGTTACAATGCAACCTGGAACTAATGGTTCGCAATCTTATAGCATCAATCTGCAAATTTTAATTTTTATGACTT
TATTGACCGTATTGCCAGGGTTGCTGATGGCAATGACGTCATTTACAAGGATAATTATTGTTCTGTCAATTCTACGGCAG
GCAATAGGGATGGCTCAGACGCCTACCAATCAAATATTAATAGGCATTGCTCTATTTATGACTTATTTCGTTATGTCACC
TGTATTCAACAAAATTAATGAAACAGCAATACAGCCCTATATGAATGAAAGGATTGATTTTTCTCTGGCATTATCCAATG
CGCAAAAGCCGCTTCGTCAGTTTATGCTAAATCAAACGAGAAAAAATGATTTATCTTTATTTGAAAAATTTGCTCACAAT
GTACCAAAAACTTTAGATGAGATTCCTATGAGTGTTCTCATTCCGGCTTTCATTACTAGCGAGCTAAAAACCGCATTTCA
AATAGGCTTTATTCTATTTTTACCCTTTTTAATTATTGATCTTGTTGTGTCCAGCCTTTTGATGGCTATGGGGATGATGA
TGCTTTCACCCTTGATTATTTCATTACCTTTTAAAATCATGTTGTTTGTGATGGTTGATGGATGGACTTTGGTTTTGGGT
TCACTTGCTTCAAGTTTTGCTCTTGCCTAG

Protein sequence :
MKIKSWLLIFILLLLLPVAGHTDPLSFPVVTMQPGTNGSQSYSINLQILIFMTLLTVLPGLLMAMTSFTRIIIVLSILRQ
AIGMAQTPTNQILIGIALFMTYFVMSPVFNKINETAIQPYMNERIDFSLALSNAQKPLRQFMLNQTRKNDLSLFEKFAHN
VPKTLDEIPMSVLIPAFITSELKTAFQIGFILFLPFLIIDLVVSSLLMAMGMMMLSPLIISLPFKIMLFVMVDGWTLVLG
SLASSFALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-13 43
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-13 43
hrcR ABA47279.1 HrcR Virulence S-PAI Protein 5e-13 42
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 2e-11 42
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 2e-11 42
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 2e-11 42
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 3e-18 41
YPO0270 YP_002345352.1 type III secretion system protein Virulence Not named Protein 1e-14 41
hrcR AAD21321.1 HrcR Virulence Hrp PAI Protein 2e-18 41
hrcR NP_640757.1 type III secretion system protein Virulence Hrp PAI Protein 2e-18 41
hrcR YP_362153.1 type III secretion system protein Virulence Hrp PAI Protein 2e-18 41
escR CAI43889.1 EscR protein Virulence LEE Protein 5e-14 41
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 7e-14 41
escR AAC31528.1 L0049 Virulence LEE Protein 4e-14 41
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 7e-14 41
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 4e-14 41
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 5e-14 41
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 5e-14 41
escR AAK26700.1 EscR Virulence LEE Protein 5e-14 41
escR AAL57527.1 EscR Virulence LEE Protein 5e-14 41
escR CAC81847.1 EscR protein Virulence LEE II Protein 5e-14 41
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 2e-13 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG2016 Protein 9e-87 98
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG1259 Protein 8e-47 62
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG2338 Protein 2e-42 55
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG2494 Protein 6e-42 54
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG2131 Protein 2e-16 43
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG0044 Protein 7e-14 42
fliP YP_127091.1 flagellar biosynthesis protein FliP VFG0827 Protein 2e-14 41