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Name : guaA (lpl1686) Accession : YP_127025.1 Strain : Legionella pneumophila Lens Genome accession: NC_006369 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 1880330 - 1881907 bp Length : 1578 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGAATGATTTGAAAAAAAGCCCATTATTAATATTAGATTTTGGTTCTCAATATACCCAATTAATTGCAAGACGCGTTCG AGAAATGGGGGTTTATTGTGAAATTTATCCTTATAATATTAATCATGAACAATTTAAAAAATTAAACCCATGTGGTGTGA TTTTATCAGGAGGTCCTTCGACAGTAACGCATGATGCCAATCCCAGGGCTCCTCAATGGCTGTTTGAGAGCGATTTGCCC TTACTGGGTATATGCTATGGGATGCAAACCATGGCTGTACAACTCGGTGGTCAAGTGCATTCATCGACGCTAAGAGAATT TGGATATGCTGAGTTGCGTTTGCATGGCCATAGTCAATTATTAAGTAATATCGAAGATCGTACCGCGATGGATGGCAGCG CTCTGCTGGATGTTTGGATGAGCCATGGTGATAAAGTCACTGAGTTACCACCAGGTTTTAAAGTGATATGTGAAACACGT AATGCACCAATTGCAGGTATGGCTGATGAAAGCCGTCAAATGTATGGTTTGCAATTTCATCCAGAAGTTACTCATACCTT GCAAGGTTTAAGAATTTTACAACGTTTTGTCGTAGATATTTGTAAAGCATCAACAGACTGGACTCCAGAGCATATTATTG ATGAAGCCATTAATAAAATCAGAGAACAGGTAGGAACTGAAAAAGTTTTACTGGGCCTATCTGGAGGCGTTGACTCTTCT GTTGTAGCCGCATTACTTCATAGAGCCATTGGAGAGCAACTGGTTTGTGTTTTCGTTGATACGGGTTTACTCAGACTTAA TGAGGCGGAGCAAGTGCTGAGCATGTTCGGTCGGCATATGGGAATACGCATTATTGCAGTCAATGCCGAAGATAAATTTT TAACTGCTTTGAAGGGAGTAACTTGCCCAGAGGAAAAGAGAAAAATTATTGGGCGTACATTTATCGAAGTCTTTGATGAG GAAGCACAGAAGCTGACTGATATAAAGTGGCTGGCTCAGGGCACAATCTACCCCGATGTCATCGAGTCTGCAGCAACAAG TACTAATGATGCAGCTGTGGTCATAAAGTCTCATCATAATGTCGGTGGCTTACCAGATACATTAAATCTTAAACTGTTGG AGCCCATTCGCGAGCTCTTTAAAGACGAAGTACGTCAAGTAGGTCTGGAATTGGGACTCCCGCATGATATGGTTTATCGA CATCCCTTTCCTGGACCTGGATTGGGTGTAAGAATTTTAGCGGAAGTAAAAAAAGAATATGCGGACATATTACGTAAAGC CGATGCTATTTTTATTGAAGAACTGCATAACGCGCAGCTTTATCATAAAATCAGTCAGGCATTTGCTGTTTTTTTACCAG TAAAGAGCGTGGGTGTGATGGGGGATGGGCGCCGATATGATTACGTAATTTGTTTAAGAGCTGTTGAGACAGTTGATTTT ATGACAGCACATTGGTCTCAATTGCCTTGGGATTTTTTAGGAAAAGTATCCAATCGAATTATTAATGAAGTAGAGGGAGT ATCACGTGTCACTTACGATATTTCTGGCAAGCCACCTGCTACCATTGAATGGGAATGA Protein sequence : MNDLKKSPLLILDFGSQYTQLIARRVREMGVYCEIYPYNINHEQFKKLNPCGVILSGGPSTVTHDANPRAPQWLFESDLP LLGICYGMQTMAVQLGGQVHSSTLREFGYAELRLHGHSQLLSNIEDRTAMDGSALLDVWMSHGDKVTELPPGFKVICETR NAPIAGMADESRQMYGLQFHPEVTHTLQGLRILQRFVVDICKASTDWTPEHIIDEAINKIREQVGTEKVLLGLSGGVDSS VVAALLHRAIGEQLVCVFVDTGLLRLNEAEQVLSMFGRHMGIRIIAVNAEDKFLTALKGVTCPEEKRKIIGRTFIEVFDE EAQKLTDIKWLAQGTIYPDVIESAATSTNDAAVVIKSHHNVGGLPDTLNLKLLEPIRELFKDEVRQVGLELGLPHDMVYR HPFPGPGLGVRILAEVKKEYADILRKADAIFIEELHNAQLYHKISQAFAVFLPVKSVGVMGDGRRYDYVICLRAVETVDF MTAHWSQLPWDFLGKVSNRIINEVEGVSRVTYDISGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-124 | 49 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-124 | 49 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-124 | 49 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 4e-112 | 48 |
