Gene Information

Name : tkt (lpl0139)
Accession : YP_125516.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 169257 - 171263 bp
Length : 2007 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAACAGTTTTACAGAATTAGCTAATGCGGTACGCATGTTAAGCATCGATGCAGTAAACCAGGCTCAATCAGGCCACCC
TGGCATGCCCTTGGGTATGGCTGATATTGCCACCGTTTTATGGAAAAAATTTCTAAAATTCAACCCCCAAAACCCGCACT
GGTTTAACAGAGATCGTTTTGTATTATCTAATGGCCATGGTTCCATGCTTCTCTATTCTTTACTGCATTTGACCGGATAC
AATCTGGATATTGGCGAGCTTAAAAACTTCCGCCAATTGCATTCAAAAACACCAGGACATCCGGAACATGGACATACTCC
CGGTGTTGAAACCACAACAGGGCCGTTAGGTCAAGGTTTGGCTAATTCAGTCGGGATGGCCTTAGCAGAACGTGTGCTGG
CCAGTACCTTTAACCACGACCACTTTAACCTGGTTGATCACTATACTTATACTTTTGCCGGTGATGGTTGCCTGATGGAA
GGCATTTCTCATGAAGCTTGTTCTTTAGCTGGCACTCTTGGTTTGGGAAAGCTCATTGTATTTTATGACGACAATGGGAT
ATCTATTGATGGCAAGGTGGAATCCTGGTTTACGGACGATACCACGTCTCGCTTTAAAGCCTACAACTGGCAAGTCATAG
GGCCCATCGATGGCCATGATGCAAATCAAATTGAGCACGCCATATCAGAAGCGCGCGAGAACACCACCCAACCTTCATTA
ATTATCTGTAAAACCGTCATAGGGCTTGGCTCCTCTGTAGCGGGCAGCGAAAAGGCACATGGCTCTCCATTGAGTGCCCA
GGACATAAGTAATGTTCGCGAATTTTTTAATTGGAAACATGCTTCTTTCGAAATTCCAGATTCGATATACAAGCAATGGA
ATCATAAAGAGCAGGGAGAAAAAGAAGAACAACTATGGCTGCAACTACTGCATGAATACCAACAGCAATATCCATCGGAA
CACGATGACTTTTTACGCCGTGCCAATGGTGACCTGCCTGATGATTGGCAGGAAATATCGGCTGGATTCCTGAAACAATG
CCTGAATAATGAAAAAGCTATAGCAACGCGTAAAGCGTCGCAGCAATGCATAGAATTTTTCGCGCCAATATTACCTGAAA
TGTTTGGCGGCTCGGCTGATTTGACTGGTTCCAATAATACGGACTGGTCAGGCAGCAAAGCCATCACGGCTCACAATTTT
TCCGGAAACTACCTTTATTATGGGGTGAGGGAATTCGCCATGGCAGCCATCATGAATGGGCTTGCTGTGCATGGAGGATT
CATTCCCTACGGCGGAACGTTCCTTGTTTTCGCAGATTATGCAAGAAATGCCATCCGTTTAAGCGCTTTAATGAAACAAA
GAGTGATATACGTATTGACTCATGATTCTATCGGTTTAGGGGAAGATGGCCCGACACACCAACCTGTAGAACACATCGCT
ATGTTAAGAATGACTCCTGGCATGACGGTCTGGCGTCCTGCTGATTTAATGGAAACCGCTGTTGCATGGCAACAATCGTT
AGAACATCATAATGGTCCGTCTGCCTTGTTACTCTCAAGACAAAATCTGCCCGCTTTAGCCCATGGCACCGATGCGGCTG
ACTTGATTAAGAAAGGTGGATACATTATTGCAGATTGTGAAGGGAAACCTGATGCTATCCTGATAGCCACTGGTTCAGAA
GTTCAACTGGCTATAACCGCAGCAGAAAAGGCAAAAGCAAGAGGTCTCCAGGTCAGGGTGGTATCCATGCCCTGTGCTGA
GCAGTTCCTTGCCCAGAGTGATGATTACAAAAACCAGATATTACCTGGTCAGGTTCGCACACGTATTGCGATAGAAGCAG
CTAGCAGTGCCTATTGGCACCAATTTGTTGGCTTTGACGGCGCTGTCATTGGGCTGGATTGTTTTGGGGTATCAGCTCCT
GCTACAGATGCTTTTAATTACCTTGGAATTACAGTAGAAAAAATTATCAATACTCTAGATACATTAACCAAACAAACAAT
GGTGTAA

Protein sequence :
MNSFTELANAVRMLSIDAVNQAQSGHPGMPLGMADIATVLWKKFLKFNPQNPHWFNRDRFVLSNGHGSMLLYSLLHLTGY
NLDIGELKNFRQLHSKTPGHPEHGHTPGVETTTGPLGQGLANSVGMALAERVLASTFNHDHFNLVDHYTYTFAGDGCLME
GISHEACSLAGTLGLGKLIVFYDDNGISIDGKVESWFTDDTTSRFKAYNWQVIGPIDGHDANQIEHAISEARENTTQPSL
IICKTVIGLGSSVAGSEKAHGSPLSAQDISNVREFFNWKHASFEIPDSIYKQWNHKEQGEKEEQLWLQLLHEYQQQYPSE
HDDFLRRANGDLPDDWQEISAGFLKQCLNNEKAIATRKASQQCIEFFAPILPEMFGGSADLTGSNNTDWSGSKAITAHNF
SGNYLYYGVREFAMAAIMNGLAVHGGFIPYGGTFLVFADYARNAIRLSALMKQRVIYVLTHDSIGLGEDGPTHQPVEHIA
MLRMTPGMTVWRPADLMETAVAWQQSLEHHNGPSALLLSRQNLPALAHGTDAADLIKKGGYIIADCEGKPDAILIATGSE
VQLAITAAEKAKARGLQVRVVSMPCAEQFLAQSDDYKNQILPGQVRTRIAIEAASSAYWHQFVGFDGAVIGLDCFGVSAP
ATDAFNYLGITVEKIINTLDTLTKQTMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 58
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 56