Gene Information

Name : pilR (lpl1182)
Accession : YP_126533.1
Strain : Legionella pneumophila Lens
Genome accession: NC_006369
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 1320293 - 1321621 bp
Length : 1329 bp
Strand : +
Note : Similar to type 4 fimbriae expression regulatory protein PilR (two-component response regulator)

DNA sequence : 
ATGACCAAAAGTAAAGTGCTTGTTATAGATGATGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGCATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATCGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCGGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGTGCTATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACCTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCTATGCAGGTTAAATTGCTACGTGCGATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGTATCCTAAGTGCAAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCATTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTTGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTACCAAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCGACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTTCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Protein sequence : 
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 7e-97 49
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 7e-97 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_126533.1 hypothetical protein BAC0467 Protein 9e-78 41
pilR YP_126533.1 hypothetical protein BAC0089 Protein 2e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_126533.1 hypothetical protein VFG1214 Protein 2e-131 60