Gene Information

Name : serS (lpp0575)
Accession : YP_122913.1
Strain : Legionella pneumophila Paris
Genome accession: NC_006368
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 623237 - 624517 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATAATCAATTACTTCGAGAGAATCCTCAATATGTAGCAACCCAATTGCTGAAGCGAGGATTTCAATTTGATGC
GGTCACTTTCAGTCAGTTGGAAGAAAAGCGTAAGGCTTTGCAAGTAAGTACGCAATCATTACAGAACGAACGAAATTTGC
GTTCGAAAGCCATCGGTGAAGCAAAATCTCGAGGTGAAAATATAGAACCTATGCGCGAAGAAGTGAATAAACTTGGCGCT
AAACTGGAGCAACAAAAGACTGAACTGGACGAGATTCTTAAGCAAATTGAGGTAATTAGCCTATCATTACCTAATATCCC
TCATGAGTCAGTACCTGTTGGTAAAGATGAATTGGATAATCAGGAAATCAGAAAATGGGGCGACGTACCTGCTTTTTCTT
TCCCTGTAAAGTCACATGATGAATTGGGTGAAGCACTAGGGCAAATGGATTTTGCGCTTGCAGCTAAAATTACGGGCAGT
CGTTTTGTCGTCATGAAAGGGCATCTGGCCCGATTACATCGGGCTTTAATTCAATTCATGCTGGATATACATATTCAGCA
ACATGGTTACCAGGAAATATATGTACCTTATATTGTTAATGCGGATAGCTTACTAGGGACTGGACAGTTACCAAAGTTTG
AGGCTGATTTATTTAAATTAACAGGTGATAATGGGTACTACTTGACGTCTACTTCAGAAATTCCAGTGACCAATACAGTA
AGGGAAATGATATTGTCCGCTGAGCAATTACCTATTCGTTATGTTTGCCATTCCCCGTGTTTTCGTAGTGAGGCGGGTTC
TTATGGCAAAGACACAAAGGGAATGATTAGACAGCATCAATTTGAGAAAGTTGAACTGGTCTGGATTACCAAACCGGAAG
ATTCTTATAATGCTTTAGAGCAACTTACTCAGCATGCTGAAGTTATTTTACAGCGTTTGAACTTGCCTTACCGAGTGGTT
GCTTTGTGTACCGGGGATATAGGCGCTGGTTCAGCCAAAACCTATGATCTTGAGGTTTGGTTGCCTAGCCAGAATACTTA
TCGAGAAATATCCTCTTGTTCCAATATGGAGGCATTTCAGGCACGCCGAATGAAAGCGCGTTTCCGCAATCCGGATACTA
ATGAGATTCAATTAGTCCACACTCTAAATGGATCAGGTTTAGCTGTTGGACGAACTTTAGTTGCCATTATGGAGAATTAT
CAAGATGAGCATGGAAACATTCATATACCGGATGCTTTGAAGCCTTATTTAGGTGGTATTGATATCATCTCTGTGAAATA
G

Protein sequence :
MLDNQLLRENPQYVATQLLKRGFQFDAVTFSQLEEKRKALQVSTQSLQNERNLRSKAIGEAKSRGENIEPMREEVNKLGA
KLEQQKTELDEILKQIEVISLSLPNIPHESVPVGKDELDNQEIRKWGDVPAFSFPVKSHDELGEALGQMDFALAAKITGS
RFVVMKGHLARLHRALIQFMLDIHIQQHGYQEIYVPYIVNADSLLGTGQLPKFEADLFKLTGDNGYYLTSTSEIPVTNTV
REMILSAEQLPIRYVCHSPCFRSEAGSYGKDTKGMIRQHQFEKVELVWITKPEDSYNALEQLTQHAEVILQRLNLPYRVV
ALCTGDIGAGSAKTYDLEVWLPSQNTYREISSCSNMEAFQARRMKARFRNPDTNEIQLVHTLNGSGLAVGRTLVAIMENY
QDEHGNIHIPDALKPYLGGIDIISVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-100 51