Gene Information

Name : lpp0308 (lpp0308)
Accession : YP_122648.1
Strain : Legionella pneumophila Paris
Genome accession: NC_006368
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 349112 - 350578 bp
Length : 1467 bp
Strand : +
Note : similar to betaine aldehyde dehydrogenase BetB

DNA sequence :
ATGGAAATTTACGAAATGTACATTGATGGAAAATTTACTTTAGCCAAAAGCGGAACTACTCGCGACATTTTTGATCCGGC
TAACGGGGAATTGATTGCAAGAGTGCCAGAAAGTGCCAAAGAAGATGCCATACTTGCTATCAAAGCAGCGAGAAAAGCCT
TCGATGAAGGAGAGTGGAGAAAATCACTGGCGCTTGATCGAGGCAAATTGTTATTCAAGCTTGCTGATTTGATTCGAGCC
AATGCTAAAATGTTGGCAGAGCTGGAAACTCGAAATTGCGGAAAGCCGTTACCCGAAGCGGAGTTTGATGTCACTGATGC
TGCCAATTGCTTTGAATTTTACGGTGGGCTTGCGACTAAAATTCATGGTGAAACGATGTCGGTTCCAGCGAATTCATTTA
GTTACGTAGTACGTGAACCCATAGGCGTGTGTGGGCAAATCATTCCATGGAATTTTCCACTGCTTATGGCGGCCTGGAAA
CTTGCTCCCGCACTTGCCGCAGGCAATACCGCGGTATTAAAACCATCAGAATTGACCCCGATAACGGCACTTGAGTTATT
CAAGTTGATTGATCAATGCGGATTTCCAGCGGGCGTGGTTAACCTCATTACTGGGACGGGTATAGGAGTTGGAGAGGAGT
TGGCAAATAATGCTATGGTGGATAAGGTTGCTTTCACCGGAGGATCGGCAACAGGCAGAAAAATCATGCAGGCAGCTACT
GGCAATTTGAAAAAAATCTCGTTAGAGCTTGGCGGAAAAAATCCAAATATTGTCTTTGCAGACTGTGACCTTGAAATGGC
AATCGACGGCGCCCTTTTTGGTGCTTTTGCAAATCAGGGGGAAGTCTGTTCTGCGGGTTCCCGCTTGCTAGTGGAGCGCT
CTATTCACAAAAAAATAGTAGAGGGAATGTTGAAAAAAATTCCAAATATCAAGCTTGGCCATGGTTTGGACGCCGGGGTA
AAAATGGGGCCTTTGGTTTCAAGTGCACATCGTGAAAAAGTGGAAAGCTATGTCAAGCTTGGAATGGAAGAAGGAGCCAA
ATTACTTTGCGGCGGTAAACGCCCGACAGGCAGTGAATTTGCAAAGGGAAATTTTTTCGAGCCAACTATTTTTGATGAAG
TGAAATCCACGATGCGCATTGCTCGTGAAGAAATTTTTGGTCCAGTACTTGTGGTCATCCCCTTTGATACAGAAGAAGAA
GCCATTCGCATTGCGAACGATACTGATTATGGCTTATCCGGGGCTGTATGGACGAAGAGCGTTACTCGGGCCCATCGAGT
CACATCTCAAATCCGTGCCGGTATTCTTTGGGTGAATCATTACCATCCAACCTATAATGAAATGCCTTGGGGCGGATACA
AACAAAGTGGAGCGGGTCGTGAGTTAGGCTTGTATGGCATTGAGAGTTACCTTGAGGTCAAGCAAGTGAATATTAACCTG
GATGAAACACCAATTGGTTGGTACTAA

Protein sequence :
MEIYEMYIDGKFTLAKSGTTRDIFDPANGELIARVPESAKEDAILAIKAARKAFDEGEWRKSLALDRGKLLFKLADLIRA
NAKMLAELETRNCGKPLPEAEFDVTDAANCFEFYGGLATKIHGETMSVPANSFSYVVREPIGVCGQIIPWNFPLLMAAWK
LAPALAAGNTAVLKPSELTPITALELFKLIDQCGFPAGVVNLITGTGIGVGEELANNAMVDKVAFTGGSATGRKIMQAAT
GNLKKISLELGGKNPNIVFADCDLEMAIDGALFGAFANQGEVCSAGSRLLVERSIHKKIVEGMLKKIPNIKLGHGLDAGV
KMGPLVSSAHREKVESYVKLGMEEGAKLLCGGKRPTGSEFAKGNFFEPTIFDEVKSTMRIAREEIFGPVLVVIPFDTEEE
AIRIANDTDYGLSGAVWTKSVTRAHRVTSQIRAGILWVNHYHPTYNEMPWGGYKQSGAGRELGLYGIESYLEVKQVNINL
DETPIGWY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-76 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-71 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpp0308 YP_122648.1 hypothetical protein VFG0082 Protein 1e-71 41