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Name : thyA (lpp2927) Accession : YP_125229.1 Strain : Legionella pneumophila Paris Genome accession: NC_006368 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 3340673 - 3341467 bp Length : 795 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGAAAACATATTTGCAATTGTTGGAGCATATTTTACAACAAGGAGTAGAAAAATCGGATAGAACGGGCACTGGAACATT ATCTGTATTTGGGTATCAAATGCGTTTTGATTTGACCAAGGGATTCCCGCTTGTCACTACTAAAAAACTACACACGAGAA GTATTGTTCATGAATTACTATGGTTTTTGCGTGGTGATACCAATATTTCTTATCTTAAGGAAAACGGGGTAACTATTTGG GATGAATGGGCAGATAATAATGGTGATTTGGGGCCTGTCTATGGAAAGCAATGGAGAAGTTGGCCAACTGCTGATGGACA CACTATTGATCAATTAAGTGATGTAGTGCAACAAATAAAGAGTAACCCTGACTCTCGTCGCTTGATTGTAAGCGCCTGGA ATGTGGGTGAATTGGATAAAATGGCTTTAATGCCTTGTCATGCCTTGTTTCAGTTTTATGTTGCAAACAACAAGTTATCC TGTCAATTGTATCAACGCTCAGCCGATGTATTTTTAGGAGTTCCTTTCAATATCGCTTCTTATTCGTTGCTTACTCATAT GGTCGCCCAACAATGTAATTTGGATGTGGCTGAGTTCATATGGACCGGGGGAGATTGTCATTTGTATCTTAATCATTTGG AGCAAGCGCAAATCCAATTAACAAGAGAACCTTTGCCATTGCCCTCCTTAACTATTAAGAGAAAACCAGCTTCTTTATTT GACTATGCTTATGAGGATTTTGAATTTTTGAATTATCAATCACATCCCGCAATTAAAGCACCTATTGCCGTTTAA Protein sequence : MKTYLQLLEHILQQGVEKSDRTGTGTLSVFGYQMRFDLTKGFPLVTTKKLHTRSIVHELLWFLRGDTNISYLKENGVTIW DEWADNNGDLGPVYGKQWRSWPTADGHTIDQLSDVVQQIKSNPDSRRLIVSAWNVGELDKMALMPCHALFQFYVANNKLS CQLYQRSADVFLGVPFNIASYSLLTHMVAQQCNLDVAEFIWTGGDCHLYLNHLEQAQIQLTREPLPLPSLTIKRKPASLF DYAYEDFEFLNYQSHPAIKAPIAV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 1e-85 | 64 |
