Gene Information

Name : smpB (lpp2898)
Accession : YP_125200.1
Strain : Legionella pneumophila Paris
Genome accession: NC_006368
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3310516 - 3310986 bp
Length : 471 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACTACCAAAAAACAACCAGATTCCACCATAGCCTTGAATAGAAAAGCTGGTTTTGATTATTTTATTGAAGATCAATA
CGAAGCAGGCCTGGTTTTGGAGGGCTGGGAAGTAAAAAGTCTGCGTGCTGGGAAAATCAATTTGTCGGATTCACACGTGA
TAATCAAATACGGTGAGGCATTCCTATTGGGCGCCCAAATACAGCCTCTTCCCACCGCATCCACTCATTTTATTCCTGAT
CCGGTCAGGACGCGCAAGCTATTGATGAATAAAAAAGAATTAAACCATCTCATTGGAAGTGTTGAAAGGCAAGGCTATAC
CATAGTCCCTCTTTCTTTGTATTGGAAAAAAAATAAAATTAAAATAAAAATTGCTCTGGCCAAAGGAAAAAAAGAGCATG
ACAAAAGAGACACGATCAAAGACAGAGAATGGCAAAGAGATCGTTCAAGAATAATGAAAAAGAACACTTGA

Protein sequence :
MTTKKQPDSTIALNRKAGFDYFIEDQYEAGLVLEGWEVKSLRAGKINLSDSHVIIKYGEAFLLGAQIQPLPTASTHFIPD
PVRTRKLLMNKKELNHLIGSVERQGYTIVPLSLYWKKNKIKIKIALAKGKKEHDKRDTIKDREWQRDRSRIMKKNT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-34 56
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-18 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-14 42