Gene Information

Name : hemC (lpp2791)
Accession : YP_125096.1
Strain : Legionella pneumophila Paris
Genome accession: NC_006368
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 3172800 - 3173729 bp
Length : 930 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGCGCAAAAATTATACGAATCGCAACGAGGCAGAGCCCGCTTGCACTATGGCAGGCTAATCATGTACGGGAAATGCT
TGTAAAGCAATGGCCAAATCTAAGCATTGAATTATTACCCATGATAACCTCTGGCGATCGGTTTCTTAAAGATAAATTAT
TATCCGCAGGAGGAAAAGGGTTATTTGTTAAAGAGTTAGAAGAAGCATTATTGGATAAAAGAGCGGACTTGGCTGTTCAT
TCGACCAAAGACATGCCAGCACAACTTCCGGATGGCCTCTCGTTGGCCGCCATTTGCAAAAGAGATAACCCTTTTGACGC
TTTAATAAGTCCCCGATTTAAGAGTCTGGATGCTCTCCCCAAAAACGCAATTATTGGTACATCAAGTCTTAGACGTCAAT
CTCAACTATTGGCTTACAATCCCAATTTGCAAATCAAAACATTAAGAGGAAACATCCATACAAGACTCAGCAAACTGGAG
TCAGGAGAGTATCAAGCCATTATTCTTGCTGCCGCAGGCTTGGAAAGAATGGGCTTGGCACATCACATCACCCAACTCAT
ACCCGACGACATTATGCTGCCTACTTGTGCTCAGGGCGCTTTATGTATTGAGTGCCGAACTGACGATTTGGAAATCCAGG
AGCTGATTCATGGCTTAAATGATCCAATTTCTGCCCTTTGTGTTCATACCGAGCGACGCGTCAACGCAAAATTAGGAGGC
AATTGCCATATACCCTTTGCTGTTTATTGTACCATTACTGCGGAGAAACTCCTCCTTTTGAGAGCAAAAGTACTTAATCT
GGATGGTTCTCAAATGATTGATGATGAGCAACAAGGGAAAATAGAAGAAGCTGAAATTATTGCAGACAGGTGTACCGAGT
CATTAATGACTAAAGGTGCAATGTCCTTATTAAGTACGATACCATCATGA

Protein sequence :
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVH
STKDMPAQLPDGLSLAAICKRDNPFDALISPRFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLE
SGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITAEKLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIADRCTESLMTKGAMSLLSTIPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-67 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-67 49