Gene Information

Name : guaA (nfa8970)
Accession : YP_117106.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 999226 - 1000800 bp
Length : 1575 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCAGAAACCCAGAGACCGGTCCTCGTCGTCGACTTCGGTGCCCAATACGCCCAGCTGATCGCTCGCCGGGTCCGCGA
GGCGAGCGTCTACTCCGAGGTGGTTCCCCATACCGCCACGGTGGAGGAGATCGCGGCGAAGAAGCCGCTCGCGGTGATCC
TGTCCGGTGGCCCGGCCAGCGTGTACGCCGAGGGCGCGCCGCAGCTGGATCCGCGGCTGTTCGACCTGAACCTGCCGGTC
TTCGGCATCTGCTACGGCTTCCAGGCGATGGCGCAGGCGCTCGGCGGCACGGTGGCCCACACCGGCACCCGCGAGTACGG
CCGCACCGAACTCAACATCGACGGTGGCGTGCTGCACGGCGGCCTGCCCACGATTCAGCCGGTGTGGATGAGCCACGGTG
ACGCGGTGACCGACGCGCCGGAGGGCTTCGAGGTGACCGGCACCACGGCGGGTGCGCCGGTCGCGGCGTTCGAGGACCGC
GCGCGGCGGCTGGCCGGTGTGCAGTACCACCCCGAGGTGTTGCATTCCCCGCACGGCCAGCAGGTGCTGAGCCGGTTCCT
GCACGAGCTGGCGGGTATCCCGGCGAGCTGGACACCGTCGAACATCGCCGATGTGCTGGTGGAGCAGGTGCGCGCGCAGG
TCGGCGACGGCCACGCTATCTGCGGCCTGTCCGGCGGCGTGGACAGCGCGGTGGCGGCGGCCCTGGTGCAGCGCGCCATC
GGCGACCGGCTGACCTGCGTTTTCGTCGATCACGGGCTGCTGCGCGCGGGCGAGCGCGAGCAGGTGCAGCAGGATTTCGT
CGCGTCCACCGGTGCCAAGCTGGTGACCGTCGACGCGGTGGACAAGTTCCTCGGTGAGCTGAAGGGCGTGACCGATCCCG
AGGAGAAGCGCAAGATCATCGGCCGGGAGTTCATCCGGTCCTTCGAGGACGCGGTGCGCCAGATCGTCGACGAGCAGGGC
GCGGCCGAGGGCAAGCAGCCCGAGGTGGAATTCCTGGTGCAGGGCACGCTCTACCCGGATGTGGTGGAGTCCGGCGGCGG
CACCGGCACCGCGAACATCAAGTCCCACCACAATGTCGGCGGACTGCCGGAGGACCTGGAGTTCGAGCTGGTCGAGCCGC
TGCGGTTGCTGTTCAAGGACGAGGTGCGCGCGGTCGGCCGCGAGCTCGGCCTGCCCGAGGAGATCGTGGCCAGGCAGCCG
TTCCCCGGGCCGGGGCTGGCGATCCGCATCATCGGCGAGGTCACCGCGGACCGGCTGGCGACGCTGCGGCAGGCCGACGC
GATCGCCCGCGAGGAGCTGACCGCGGCCGGGCTGGACCGGCAGATCTGGCAGTGCCCGGTGGTGTTGCTGGCCGACGTGC
GCAGTGTCGGGGTGCAGGGCGACGGCCGCACCTACGGTCATCCGATCGTGCTGCGTCCGGTGTCCAGCGAGGACGCGATG
ACCGCGGATTGGACCCGGCTGCCCTACGAGGTGCTCGAGCGGATCTCGACCCGGATCACCAACGAGGTCGCCGAGGTGAA
CCGCGTGGTGCTGGATGTGACGAGCAAGCCGCCGGGGACCATCGAGTGGGAGTGA

Protein sequence :
MAETQRPVLVVDFGAQYAQLIARRVREASVYSEVVPHTATVEEIAAKKPLAVILSGGPASVYAEGAPQLDPRLFDLNLPV
FGICYGFQAMAQALGGTVAHTGTREYGRTELNIDGGVLHGGLPTIQPVWMSHGDAVTDAPEGFEVTGTTAGAPVAAFEDR
ARRLAGVQYHPEVLHSPHGQQVLSRFLHELAGIPASWTPSNIADVLVEQVRAQVGDGHAICGLSGGVDSAVAAALVQRAI
GDRLTCVFVDHGLLRAGEREQVQQDFVASTGAKLVTVDAVDKFLGELKGVTDPEEKRKIIGREFIRSFEDAVRQIVDEQG
AAEGKQPEVEFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPEDLEFELVEPLRLLFKDEVRAVGRELGLPEEIVARQP
FPGPGLAIRIIGEVTADRLATLRQADAIAREELTAAGLDRQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAM
TADWTRLPYEVLERISTRITNEVAEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 79
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-137 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-137 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-137 52