Gene Information

Name : nfa6200 (nfa6200)
Accession : YP_116829.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Virulence
Product : hydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 641722 - 643332 bp
Length : 1611 bp
Strand : -
Note : -

DNA sequence :
GTGACGACAACCACCGACCATCGGGACGGCTACGTGCCCTTCCCCGCCGAGACGGCCGAGGCGTACCGGGCCGCGGGCTA
TTGGACCGGCAGGCCGCTGGGCGACCTGTTGCGCGCCACCGCGAGCGCCCATCCCGGCCGCACCGCCCTGCTCACCGACG
ACGGCGCGCGCGACTACGCCTGGGTCGACGCCGAGGCCGACCGGATGGCCCACGGCCTGCTCGCGCTGGGCATCGCCCCG
GGCGACCGGGTGGTCGTCCAGCTCCCCAACGTGCCCGAATTCCTCACCGTGCTGTTCGGTCTGCTCCGTGCCGGCATCAT
CCCGGTGCTGACCCTGCCCGCCCATCGCCGGGCCGAGATCGAGCACCTGGCCACGCTGTCGGAGGCCGTCGCCTACATCA
TCGCCGACCGGCAGGGCGATTTCGACTACCGCGAACTGGCCGCGACCGTGTGCGACAACGTCCCGAGCCTGCGGCACGTG
CTCGTCCTCGGCGACGCGGGCCCGTTCACCGACCTGAGCGGCATTGCCCGCGACGGCGATTCGCTGCCCGAGATCGACCC
GAGCGACATCGCGCTGATGCTGGTCTCCGGCGGCACCACCGGCCTGCCGAAGCTGATCGCGCGCACCCACGACGACTACG
TCTACAACGCCACCGCCAGCGCCGAGCTCTGCGAACTCACCGCCGAGGACGTCTACCTGGCGACCCTGCCCGCCGCGCAC
AACTTCCCGCTGGCCTGCCCCGGCATCCTGGGCAGCGTGAGCGTCGGCGCGGCGGTCGCCTTCGTCACCGATCCCAGCCC
GGAGAACGCCTTCGCCGTCATCGAACGCCACCGGGTGACCGTCACCGCCGTGGTGCCGCCGCTGGCCCAGTTGTGGTGCG
CGGCCGTGGAATGGGAGGAGGCCGACCTCGGTTCGCTGCGGCTGCTGCAGGTGGGCGGCGCGCGCCTGGCCGACGTGAAC
GCCAGGGAGGTCACCCCCGCGCTGGGCGCGACGTTGCAGCAGGTGTTCGGCATGGCCGAGGGCCTGCTCAACTACACCCG
TCTCGACGACCCCGAGGACCTGATCTGCACCACGCAGGGCCGCCCGCTCTCCCCCGCCGACGAGGTGCGCGTCGTCGACG
GCGAGGGCAACGACGTGGCGCCCGGCGAGGAGGGTGAGCTGCTGACCCGCGGCCCCTACACCATTCGCGGCTATTACCGC
GCCCCCGAGCACAACGCCCGCGCGTTCACCCCCGACGGCTACTACCGCAGCGGGGACCTGGTGCGGGTGCTGCCGTCGGG
ACACCTGATCGTCTCCGGGCGGATCAAGGACGTCATCAACCGCGGCGGGGAGAACATCTCCTGCGACGAGCTCGAGGAGC
ACCTGCTCGCGTACCCGGCCGTGCGGCACGCGGCCGCGGTCGGGCTGCCCGATGCCGCCCTGGGCGAAAAGGTCTGCGCG
GTACTGGTCGTCGACGGTGACATGCCGAGTCTGGCGGAGGTCAAGAAGTTCCTGCTCGGCCGCGGCCTGGCCACCTTCAA
GTTGCCCGACGTGCTGCGCCAGGCCGACACCCTGCCGCTCACCGCGGTCGGCAAGATCGACAAGAAGGTGCTGCGGGCCA
CCCAGTCCTGA

Protein sequence :
MTTTTDHRDGYVPFPAETAEAYRAAGYWTGRPLGDLLRATASAHPGRTALLTDDGARDYAWVDAEADRMAHGLLALGIAP
GDRVVVQLPNVPEFLTVLFGLLRAGIIPVLTLPAHRRAEIEHLATLSEAVAYIIADRQGDFDYRELAATVCDNVPSLRHV
LVLGDAGPFTDLSGIARDGDSLPEIDPSDIALMLVSGGTTGLPKLIARTHDDYVYNATASAELCELTAEDVYLATLPAAH
NFPLACPGILGSVSVGAAVAFVTDPSPENAFAVIERHRVTVTAVVPPLAQLWCAAVEWEEADLGSLRLLQVGGARLADVN
AREVTPALGATLQQVFGMAEGLLNYTRLDDPEDLICTTQGRPLSPADEVRVVDGEGNDVAPGEEGELLTRGPYTIRGYYR
APEHNARAFTPDGYYRSGDLVRVLPSGHLIVSGRIKDVINRGGENISCDELEEHLLAYPAVRHAAAVGLPDAALGEKVCA
VLVVDGDMPSLAEVKKFLLGRGLATFKLPDVLRQADTLPLTAVGKIDKKVLRATQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-109 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-109 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 8e-112 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-111 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-111 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-111 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-111 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-111 50
ybtE CAA21394.1 - Virulence HPI Protein 1e-111 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nfa6200 YP_116829.1 hydroxybenzoate-AMP ligase VFG1817 Protein 1e-134 57
nfa6200 YP_116829.1 hydroxybenzoate-AMP ligase VFG0168 Protein 8e-104 49
nfa6200 YP_116829.1 hydroxybenzoate-AMP ligase VFG0932 Protein 1e-98 45