Gene Information

Name : nfa6190 (nfa6190)
Accession : YP_116828.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Virulence
Product : salicylate synthase MbtI
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 640308 - 641624 bp
Length : 1317 bp
Strand : +
Note : catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function

DNA sequence :
TTGTCGACCACGGACGAGCGCTCGCGCGTTGAGTATGTGACCGATCCGGCGGCAGCGATGTCCCGGTTGGCGTCGGCGGA
CCGGTTCGGCGAATACGTGATGTACGAGCGCCCCGGGCAATGGGTGTTCGCGGCCGACCCGATCGGCAGCATCGAACTCG
ACGCCAGCGAACTGCGGGTCACGTGGGAAGGCGAGACCACGGTGTCGCGGTGGGAGGGCTCGCCCGCGCGCGCCCTGGAC
CGCGCGCTCGGCATGCTTCCCGCGGGCTCGGCCAAGGCCTACGGCTGGATCGGTTTCGAGTTCTGCGCGTGGGCGCTCGC
GGCCACCGACCACGTCGACGAGCGGACCTCGCTGGCGCACCTGATGATTCCGCGCATCGAGGTGGTCGTGGACGAGTCCG
GCGTGCGGATCGGCGGCGCGACGCCCTCGGAGACCGCCGACATCCACGATCTGATCGCGGCCGCCCAGGACACCGAGCTG
CCGCAGCCGCATCCGATCGACGTGCGCATCGATCCCACCGGCTATCGGGACCGGGTGGCCGAGGCGGTCGCCGAGATCGG
CGCGGGCCGCTACCAGAAGGTGATCCTGTCGCGGAAGGTCGACCTGCCCTTTACCGTCGACGTGCCCGCCACCTACCGGC
TCGGCCGCGCGAACAACACGCCCGCGCGCTCGTTCCTGCTGCGGCTGGGCGGCCTGGAATCGGCGGGCTTCAGCCCCGAA
CTGGTCGCCTCCGTCGACGAGGACCGGGTGGTCACCACCGAGCCGCTGGCGGGCACCCGCGCCTTCGGCCGCGGCCACGA
GGTCGACATGGCCGCCCGCGCCGACCTGGTGAGCGACCCGAAAGAGATCGTGGAGCACGCCATCTCGGTGCAGACCTCCT
TCGCCGAGATCAGCGCGGTCGCCGATCCGGGCACCCCCGCGGTGTCGGACTTCATGGCCGTGCGCGAGCGCGGCAGCGTG
CAGCACCTGGCCTCGACCGTGCGCGGCAGGCTCGCGGCCGACCGCTCCAGCTGGGATGCCCTGGAAGTGCTGTTCCCGTC
GGTCACCGCGTCGGGCATCCCCAAGCGCGAGGGCGTCGACTCGGTCTTCCGGCTCGACGGCGCACCGCGCGGCCTGTACT
CCGGTGCGGTGGTGACCGTTTCGCCGACCACCGGCGCGCTGGAGGCGACGCTGGTGCTGCGGGCGGTCTACCAGACCGCC
GAGGGCGCGTGGCTGCGCGCGGGCGCGGGTGTGGTCGGGCAGTCGCGGCCGGAGCGGGAATTCGAGGAGACCTGCGAAAA
GCTCGGCAGCATCGCGCCCTACGTGGTCAAGGCCTGA

Protein sequence :
MSTTDERSRVEYVTDPAAAMSRLASADRFGEYVMYERPGQWVFAADPIGSIELDASELRVTWEGETTVSRWEGSPARALD
RALGMLPAGSAKAYGWIGFEFCAWALAATDHVDERTSLAHLMIPRIEVVVDESGVRIGGATPSETADIHDLIAAAQDTEL
PQPHPIDVRIDPTGYRDRVAEAVAEIGAGRYQKVILSRKVDLPFTVDVPATYRLGRANNTPARSFLLRLGGLESAGFSPE
LVASVDEDRVVTTEPLAGTRAFGRGHEVDMAARADLVSDPKEIVEHAISVQTSFAEISAVADPGTPAVSDFMAVRERGSV
QHLASTVRGRLAADRSSWDALEVLFPSVTASGIPKREGVDSVFRLDGAPRGLYSGAVVTVSPTTGALEATLVLRAVYQTA
EGAWLRAGAGVVGQSRPEREFEETCEKLGSIAPYVVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 5e-67 41
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 5e-67 41
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 5e-67 41
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 5e-67 41
ybtS CAA21385.1 - Virulence HPI Protein 5e-67 41
irp9 CAB46570.1 salicylate synthetase, Irp9 Virulence HPI Protein 5e-67 41
irp9 YP_001006810.1 salicylate synthase Irp9 Not tested HPI Protein 2e-66 41
ybtS NP_993012.1 salicylate synthase Irp9 Not tested HPI Protein 2e-66 41