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Name : leuS (nfa55240) Accession : YP_121740.1 Strain : Nocardia farcinica IFM 10152 Genome accession: NC_006361 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 5849497 - 5852349 bp Length : 2853 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGCAGGACACTCGTGCAACCGAAAGCGATGTACCCGAGCACCGGTACAACGCCGCGCTCGCGGGCCGCATCGAGCGCCG GTGGCAGCAGCGCTGGCTCGAGCGCGGGACGTTCCACGCCCCGAACCCCACCGGGCCGCTCGCCGGGCCGACGGCGACGC TGCCCGCGGACAAGCTGTTCGTGCAGGACATGTTCCCGTACCCGTCGGGCGCGGGCCTGCACGTCGGCCACCCGCTGGGC TACATCGCCACCGACGTGTTCGCCCGCTATCACCGCATGCGCGGGCGCAACGTGCTGCACGCCCTCGGCTACGACGCCTT CGGCCTGCCCGCCGAGCAGTACGCGGTGCAGACCGGCGCACACCCGCGCGACACCACCGAATCCAACATCGCCACCATGC AGCGGCAGCTGGACCGGCTCGGCCTCGGCCACGACCGCCGCCGCTCCTTCGCGACCACCGACCCCGAGTACTACCGCTGG ACCCAGTGGATCTTCCTGCAGATCTACAACGCCTGGTACGACCTGGAGCTGAACCGGGCCCGCCCGATCAGCGAACTGGA GGAACAGTTCGCCTCCGGCGCCCGCCCGGCGCCCGACGGCAAGGACTGGGCGAGCATGTCGCAGGCCGAGCGCGCCGCCG TGATCGATTCCTATCGCCTGGTGTACCAGACGGATTCGATGGTGAACTGGTGCCCCGGCCTGGGCACGGTGCTGTCCAAC GAGGAGGTCACCGCGGAGGGCCGCAGCGAGCGCGGCAACTTCCCGGTGTTCCGTAAGCGGTTGTGGCAGTGGATGATGCG CATCACCGCCTACGCCGACCGCCTGGTCGACGACCTGGACCTGCTGGACTGGCCGGAGAACGTCAAGGCCATGCAGCGCA ACTGGATCGGCCGTTCGCGGGGCGCGCAGGTGCGCTTCGACTCCCCGGCCGGGCAGATCGAGGTGTTCACCACCCGCCCG GACACCCTGTTCGGCGCCACCTACGTGGTGCTGGCGCCCGAGCACGACCTGGTCGACGCGCTGGCCGCAGCGCAGTGGCC CGCCGACACCGACCCCCGCTGGACCGGCGGTGCGGCCACCCCCGCCGAGGCGGTGGCGCAGTACCGCAAATCCATCGCGG CCAAGTCGGATCTGGAGCGGCAGGAGAACAAGGAGAAGACCGGCGTCTTCCTCGGCGTGCACGCGGTCAACCCGGTCAAC GGCGCGCGGGTGCCGATCTTCATCGCCGACTACGTGCTCAGCGGCTACGGCACCGGTGCGATCATGGCGGTGCCCGGCCA CGACCAGCGCGACTGGGAATTCGCCACCGCCTTCGGCCTGCCGATCGTGGAGGTGATCTCCGGCGGCGACATCACCGCCG CCGCGCACACCGGTGAGGGCGAGCTGGTGAACTCCGACTACCTGAACGGGCTGTCGGTGGAGGAGGCCAAGGCCACCGTC ATCGGCAGGCTGGAGGCCGACGGGCACGGCACCGGCACCATCCAGTACAAGCTGCGCGACTGGCTGTTCGCGCGCCAGCG GTACTGGGGCGAGCCGTTCCCCATCGTCTACGACGAGGACGGCGCACCGCACGCGCTGCCGGAATCCATGCTGCCCGTGC GGCTTCCGGAGCTGGACGACTTCGCCCCGGTGACCTTCGACCCCGACGACGCCGATTCCGAGCCGTCGCCGCCGCTGGCG AAGGCCACCGACTGGGTGCACGTCGAGCTGGATCTGGGCGACGGGCCCAAGAAGTACCGGCGCGACACCAACGTCATGCC GAACTGGGCGGGCAGCTCCTGGTACCAGCTGCGCTACGCCGACCCCACCAACGCGGACGCGTTCTGCGCCAAGGAGAACG AGCAGTACTGGCTCGGCCCCCGCACCGCCGAGCACGGCCCGGACGACCCGGGCGGGGTGGACCTCTACGTCGGTGGCGTC GAACACGCCGTGCTGCACCTGCTCTACGCGCGGTTCTGGCAGAAGGTGCTCTTCGACCTGGGCTACGTCAGCAGCAGTGA GCCCTATCGGCGGCTGTTCAACCAGGGCTACATCCAGGCCTTCGCCTACACCGACCCGCGCGGCGCCTACGTGCCGGCCG CCGAGGTGGTGGAGCGCGACGGCGCGTTCTTCTGGACCGATGCCACCGGCACCGAGATCGAGGTGTCCCAGGAGTACGGC AAGATCGGCAAATCGCTGAAGAACGCGATCTCCCCCGACGAGGTGTGCGACCAGTTCGGCGCGGACACCTTCCGGTTCTA CGAGATGTCGATGGGTCCGCTGGACACCTCGCGGCCGTGGTCGACCAAGGACGTCGTGGGCGCGCACCGGTTCCTGCAGC GGGTGTGGCGACTGGTGGTGGACGAGGAGACGGGCGCGAGCCGCGTCACCGAGGACGCGCCGACCGACGAGACGCTGCGC TTCCTGCACCGGACGATCGCGGGCGTCGACGAGGATTTCGCCGCGCTGCGCGACAACACCGCCGGGGCCAAGCTGATCGA GCTGACCAACCATCTCACCAAGAGCTACCCGAGCGGCACGCCGCGCGCGGCCGTCGAGCCGCTGGTGCTGATGCTGGCCC CGCTGGCGCCGCACGTCGCCGAGGAACTGTGGGAACGCCTGGGGCACAGCGAATCCCTGGCGCACGGTCCGTTCCCGGTG GCCGATCCGGCGTGGCTGGTGGAGGAGACGGTCGAGTACCCGATCCAGGTGAACGGCAAGGTGCGCAGCCGCATCCAGGT GCCCGCCGACGCCGACAACGCCGCCATCGAGGCCGCCGCGCTGGCCGACGAGAAGATCGCGGCCCTGCTCGCCGGCGCCA CCCCGCGCAAGCTGATCGTCGTCCCCGGCCGCCTGGTGAACATCGTCGCCTGA Protein sequence : MQDTRATESDVPEHRYNAALAGRIERRWQQRWLERGTFHAPNPTGPLAGPTATLPADKLFVQDMFPYPSGAGLHVGHPLG YIATDVFARYHRMRGRNVLHALGYDAFGLPAEQYAVQTGAHPRDTTESNIATMQRQLDRLGLGHDRRRSFATTDPEYYRW TQWIFLQIYNAWYDLELNRARPISELEEQFASGARPAPDGKDWASMSQAERAAVIDSYRLVYQTDSMVNWCPGLGTVLSN EEVTAEGRSERGNFPVFRKRLWQWMMRITAYADRLVDDLDLLDWPENVKAMQRNWIGRSRGAQVRFDSPAGQIEVFTTRP DTLFGATYVVLAPEHDLVDALAAAQWPADTDPRWTGGAATPAEAVAQYRKSIAAKSDLERQENKEKTGVFLGVHAVNPVN GARVPIFIADYVLSGYGTGAIMAVPGHDQRDWEFATAFGLPIVEVISGGDITAAAHTGEGELVNSDYLNGLSVEEAKATV IGRLEADGHGTGTIQYKLRDWLFARQRYWGEPFPIVYDEDGAPHALPESMLPVRLPELDDFAPVTFDPDDADSEPSPPLA KATDWVHVELDLGDGPKKYRRDTNVMPNWAGSSWYQLRYADPTNADAFCAKENEQYWLGPRTAEHGPDDPGGVDLYVGGV EHAVLHLLYARFWQKVLFDLGYVSSSEPYRRLFNQGYIQAFAYTDPRGAYVPAAEVVERDGAFFWTDATGTEIEVSQEYG KIGKSLKNAISPDEVCDQFGADTFRFYEMSMGPLDTSRPWSTKDVVGAHRFLQRVWRLVVDEETGASRVTEDAPTDETLR FLHRTIAGVDEDFAALRDNTAGAKLIELTNHLTKSYPSGTPRAAVEPLVLMLAPLAPHVAEELWERLGHSESLAHGPFPV ADPAWLVEETVEYPIQVNGKVRSRIQVPADADNAAIEAAALADEKIAALLAGATPRKLIVVPGRLVNIVA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 8e-139 | 48 |
