Gene Information

Name : thiC (nfa53160)
Accession : YP_121532.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 5617123 - 5618766 bp
Length : 1644 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGCATCCGCCGATCGCGTCACCGCACCCGTCGACACCGTCACCACCGGCCCCATCGAGGGCAGCGTCAAGCACTACCG
CGAGGTGGACGGGCTCCGAATCCCGGTGCGGCGCATCAATCTCACCAACGGCGAGACCTTCGACGTGTACGACACCTCGG
GCCCGTACACCGACGAGAACGCCACCATCGACCTGGAGGCCGGTCTGCCCAAGCTGCGCGACAGCTGGGACAAGCCGACC
GTCGCGGGCCCGCGCACCCAGCTCGCCTGGGCCCGCGCCGGCATCGTCACCCCGGAGATGCGCTTCATCGCCGCCCGCGA
GGGCGTCGAACCGGAACTGGTGCGCGCGGAGGTGGCGGCCGGTCGTGCCGTCATCCCGGCCAACCACAACCATCCCGAAC
TCGAGCCGACCATCATCGGCAAGAAGTTCCTGGTGAAGATCAACGCCAACATCGGCAACTCGGCGGTCTCCTCTTCGATC
GCCGAGGAGGTGGAGAAGATGGTGTGGGCCACCCGCTGGGGCGCCGACACCATCATGGACCTGTCCACCGGCAAGAACAT
CCACGAGACCCGCGAGTGGATCCTGCGCAACTCGCCGGTGCCGGTCGGCACCGTGCCGATCTACCAGGCGCTGGAGAAGG
TCAACGGCGATCCGGCCGCGCTCACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGGCCGAGCAGGGCGTGGACTAC
ATGACCGTGCACGCGGGCGTACTGCTGCGCTACGTGCCGTTGACCGCCAAGCGCGTCACCGGCATCGTCTCGCGTGGCGG
CTCGATCATGGCGGCCTGGTGCCTGGCGCACCATCGGGAGTCGTTCCTGTACACCCATTTCGAGGAACTGTGCGAGATCC
TGGCCCGCTACGACGTCACCTTCTCCCTCGGCGACGGCCTGCGGCCCGGCTCCGTCGCCGACGCCAACGACGAGGCGCAG
TTCGCCGAGCTGCGCACCCTCGGTGAACTCACCAAGATCGCGAAATCCCATGGCGTGCAGGTGATGATCGAAGGCCCCGG
CCATGTGCCGATGCACAAGATCGTGGAGAACGTGCGGCTCGAGGAGGAGCTGTGCGAGGAGGCGCCGTTCTACACCCTCG
GCCCGCTGGCCACCGACATCGCACCCGCCTACGACCACATCACCTCGGCCATCGGCGCCGCGATCATCGCCCAGGCGGGC
ACCGCGATGCTCTGCTACGTCACCCCCAAGGAGCATCTGGGCCTGCCCAACCGCGACGACGTGAAGACCGGCGTGATCAC
CTACAAGATCGCCGCGCACGCCGCCGACCTGGCCAAGGGCCACCCGCACGCCCAGCAGCGCGACGACGCGCTGTCCAAGG
CGCGCTTCGAGTTCCGCTGGCGCGACCAGTTCGCGCTCTCGCTCGATCCCGACACCGCGCGCGAGTACCACGACGAGACG
ATGCCCGCCGAGCCCGCCAAGACCGCGCACTTCTGCTCGATGTGCGGCCCGAAGTTCTGCTCGATGCGCATCTCCGCCGA
CGTCCGCGAGTACGCCGAGGCCAACAACCTCACCGACGTCGCGGCCATCGAGGCCGGCATGGCCGCCAAGTCCGCCGAGT
TCGCCGAATCCGGCGGCAAGGTCTACCTGCCCGTCGTGTCCTGA

Protein sequence :
MASADRVTAPVDTVTTGPIEGSVKHYREVDGLRIPVRRINLTNGETFDVYDTSGPYTDENATIDLEAGLPKLRDSWDKPT
VAGPRTQLAWARAGIVTPEMRFIAAREGVEPELVRAEVAAGRAVIPANHNHPELEPTIIGKKFLVKINANIGNSAVSSSI
AEEVEKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVNGDPAALTWEIYRDTVIEQAEQGVDY
MTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGSVADANDEAQ
FAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAG
TAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPHAQQRDDALSKARFEFRWRDQFALSLDPDTAREYHDET
MPAEPAKTAHFCSMCGPKFCSMRISADVREYAEANNLTDVAAIEAGMAAKSAEFAESGGKVYLPVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-157 64
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-157 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 5e-151 60