Gene Information

Name : smpB (nfa44800)
Accession : YP_120695.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 4644275 - 4644757 bp
Length : 483 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
TTGACCGTTATGAAGGAGAAGGGGCGAAAGGTCATCGCGACCAACCGCCGGGCGCGGCACAACTACACGATCCTGGACAC
CTACGAGGCCGGGATCGTGCTGGTCGGTACCGAGGTCAAGAGTCTGCGCGAGGGCAAGGCCTCGCTGGTGGACGCCTTCG
CGACCGTCGACAACGGCGAGGTGTGGCTGCGCGGCCTGCACATCCCCGAGTTCAGCCACGGCACCTGGACCAATCATTCG
CCCCGCCGCGTGCGAAAGCTGCTGTTGCACAAGCGCGAGATCGAACGGCTGGTCGGTAAGTCGCGCGAGGGCAACCAGAC
GCTGGTGCCGCTGTCGATGTACTTCTCCGACGGCAAGGTCAAGGTCGAGCTGGCGTTGGCGCGCGGTAAGCAGGACTACG
ACAAGCGCCAGGATCTGGCCCGCCGCACCGCCGAACGCGAGGTGACCCGTGAGCTGGGCCGTCGCGTCAAGGGCATGCGC
TGA

Protein sequence :
MTVMKEKGRKVIATNRRARHNYTILDTYEAGIVLVGTEVKSLREGKASLVDAFATVDNGEVWLRGLHIPEFSHGTWTNHS
PRRVRKLLLHKREIERLVGKSREGNQTLVPLSMYFSDGKVKVELALARGKQDYDKRQDLARRTAEREVTRELGRRVKGMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 6e-50 74
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 6e-30 55
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-20 42