Gene Information

Name : nfa4150 (nfa4150)
Accession : YP_116621.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Virulence
Product : Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 433460 - 436015 bp
Length : 2556 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGAGGCGCGTCGTTGTCCTGGCCCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTTGGCCTGATCCATGAGGGTGAAGGTGTCGCGGCCAAGTCGCTGGAGTCCCTCGGCA
TTTCGCTCGAGGGTGTGCGCAGCCAGGTCGAGGAGATCATCGGTCAGGGCCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACCCCGCGCGCCAAGAAGGTGCTGGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTCATCCGCGAGGGCGAGGGCGTGGCGGCCCAGGTGCTGGTCAAGCTCGGCGCCGACCTGAACCGGG
TCCGTCAGCAGGTCATCCAGCTGCTGTCGGGCTACCAGGGCAAGGAGCCGGTGGAGTCGGGCGCGCGTGGCGAGACGGGC
ACCCCGTCCACCTCGCTGGTGCTCGACCAGTTCGGCCGCAACCTCACCCAGGCCGCGCTCGAGGGCAAGCTCGACCCGGT
GATCGGCCGCTCGAAGGAGATCGAGCGGGTCATGCAGGTGCTCAGCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCG
AGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTGGCGCAGGCCATCGTCAACGGCGAGGTTCCCGAGACCCTCAAG
GACAAGCAGCTCTACACCCTCGACCTCGGTTCGCTGGTCGCGGGCAGCCGCTACCGCGGTGATTTCGAGGAGCGCCTGAA
GAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCCGGTG
CCGCCGAGGGCGCGATCGACGCCGCCTCCATCCTCAAGCCGAAGCTGGCCCGCGGCGAGCTGCAGACCATCGGCGCCACC
ACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGCCGCTTCCAGCCGGTGCAGGTGGGCGAGCC
GACCGTCGAGCACACCATCAACATCCTCAAGGGCCTGCGCGACCGCTACGAGGCGCACCACCGGGTGTCCATCACCGACG
GCGCGCTGGTCGCCGCCGCCACCCTGGCCGACCGGTACATCAACGACCGGTTCCTGCCGGACAAGGCGATCGACCTGATC
GACGAGGCGGGCGCGCGCATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGACAAGATCGCCGA
CGCGCGCCGGGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGCGCCTGCGCGACAAGGAGAAGCAGC
TCGTCGCCAAGCGCGCCGAGCGGGAGAAGCAGTGGCGCTCCGGTGACCTGGACGTCGTGGCCGAGGTCGACGACGAGCAG
ATCGCCGAGGTGCTGGCCAACTGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGAGGAGACCACCCGTCTGCTCCGCAT
GGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGATGCGGTCAAGGCCGTCTCCAAGGCCATCCGCCGCACCCGCG
CCGGCCTGAAGGATCCGAAGCGTCCGTCCGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCC
AAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGACCGCTTCAC
CGCCTCGCGGCTGTTCGGTGCCCCTCCGGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGCGCCGCA
AGCCGTTCTCGGTCGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACACCCTGTTGCAGGTCCTCGAG
GACGGCCGCCTCACCGACGGCCAGGGCCGCACGGTCGACTTCAAGAACACGGTGCTGATCTTCACCTCGAACCTCGGCAC
GCAGGACATCTCGAAGGCGGTCGGCCTCGGCTTCTCGCAGTCGAACAACGAGGGCTCGAACTACGAGCGGATGAAGCTCA
AGGTCAACGACGAGCTGAAGAAGCACTTCCGGCCCGAGTTCCTCAACCGCATCGACGACGTGATCGTCTTCCACCAGCTC
ACCAACGAGCAGATCGTCGAGATGGTGGACCTGATGATCGGCCGCGTCGCCACGCAGCTGAAGAACAAGGACATGGCGAT
CGAGCTCACCCCGACCGCCAAGAACCTGCTCGCCAAGCGTGGCTTCGACCCCGTGCTCGGTGCCCGGCCGCTGCGCCGCA
CCATCCAGCGCGAGATCGAGGACCAGCTGTCGGAGAAGATCCTCTTCGGCGAGATCGGCCCCGGCCAGACCATCCTGGTC
GATGTCGAGGGCTGGGACGGCGAAGGCTCCGGCGAGGACGCCAAGTTCACCTTCACCGGCAAGGCGAAGCTGACCAAGGC
CCCCACCGAGGAGAAGCCCGAGGTCGTCCTCACCGGCGCCGCCGAAGGCCCCTCCGAAGCCGCCGCCGGCGAGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEPVESGARGETG
TPSTSLVLDQFGRNLTQAALEGKLDPVIGRSKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVNGEVPETLK
DKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGAT
TLDEYRKYIEKDAALERRFQPVQVGEPTVEHTINILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAIDLI
DEAGARMRIRRMTAPPDLREFDDKIADARREKESAIDAQDFEKAARLRDKEKQLVAKRAEREKQWRSGDLDVVAEVDDEQ
IAEVLANWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELS
KALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLE
DGRLTDGQGRTVDFKNTVLIFTSNLGTQDISKAVGLGFSQSNNEGSNYERMKLKVNDELKKHFRPEFLNRIDDVIVFHQL
TNEQIVEMVDLMIGRVATQLKNKDMAIELTPTAKNLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGEIGPGQTILV
DVEGWDGEGSGEDAKFTFTGKAKLTKAPTEEKPEVVLTGAAEGPSEAAAGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nfa4150 YP_116621.1 Clp protease VFG0079 Protein 0.0 61
nfa4150 YP_116621.1 Clp protease VFG0080 Protein 8e-146 51