Gene Information

Name : lysS (nfa4110)
Accession : YP_116617.2
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 429461 - 431029 bp
Length : 1569 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGCACCCCGAACACGCCTTCGTCCGGTCGCTCCGCGGGTTCGGCTCCTGCGGGGCAATCCAGCCGACCAGCCCAGGA
TGTCGACGACGTCCCGGAGCAGATGCGGATTCGCCGGGAGAAGCGCGAGCGGTTGCTCGAGGCGGGGACCGAGGCCTACC
CGGTGGTCGTGCCGCGCACGCACAGCCTGGCCGAGATCCGCGCCGCCCACCCGGACCTGGCGCCGGACACGCAGACCGGT
CAGCAGGTCGGCGTCGCGGGCCGCGTCATCTTCCTGCGCAACACCGGCAAACTGTGCTTTGCCACCCTGCAGGAGGGTGA
CGGCACCAAGCTGCAGGCGATGATCAGCCTCAACGGGGTCGGCGCGGACGCGCTGGCCGCCTGGAAAGCCGATGTCGACC
TGGGCGACTTCGTGTTCGTGCACGGCGAGGTGATCGCTTCGCGCACCGGCGAATTGAGCGTTATGGCCGATTCCTGGTCG
ATGGCGGCGAAATCGCTGCGGCCGTTGCCGGTGGCGCACAAGGAGATGAACGAGGAGTCCCGGGTCCGTCAGCGCTACGT
GGACCTCATCGTGCGCCCGGAGGCCAGGCAGATGGCCAGGACCCGGGTGGCCGTCGTGCGTGCCCTGCGCAACGCGCTGG
AGCGCCGCGGATTCCTCGAGGTCGAGACGCCGATGCTGCAGACGCTGCACGGTGGTGCGGCCGCGCGCCCGTTCGTCACC
CATTCCAACGCCCTCGACATGGACCTCTACCTGCGCATCGCGCCGGAGTTGTTCCTGAAGCGCTGTGTGGTGGGCGGACT
GGAGAAGGTCTTCGAGATCAACCGGAACTTCCGCAACGAGGGTGCCGACTCCACCCATTCGCCGGAGTTCGCGATGCTGG
AAACCTATGAGGCGTACGGCACCTACGACGACTCCGCCACGATGATCCGGGAATTGATCCAGGAGGTGGCACAGGAGGCT
TTGGGCACCCAGGTGGTGACCCTGGCCGACGGCACCGAATACGATCTTCGCGGCGAGTGGGCGACCGTGGAGATGTATCC
GTCGCTGTCGGCCGCCCTCGGCGAGCCGGTGACTCCGGAAACCACGGTCGAGGAATTGCGTGCCATCGCAGCGCGTGTCG
GGCTGGAAATTCCGGAGGAGAAGGGGTACGGCCACGGCAAACTGGTCGAAGAACTCTGGGAACACCAGTACGGCGACAAG
CTGTATGCCCCGACTTTCGTTCGCGACTTCCCGGTGGAGACCTCTCCGCTCACCCGGCAACATCGCAGCAAGCCCGGCGT
GACCGAGAAGTGGGATCTGTATGTGCGCGGCTTCGAGCTGGCCACCGGTTATTCCGAACTGGTCGACCCGGTGATCCAGC
GCGAGCGGTTCGTCGATCAGGCCAGACTCGCGGCCCAGGGGGACGACGAGGCAATGGTCCTGGACGAGGACTTCCTCGCC
GCGATGGAGCACGGCATGCCGCCGACCACCGGAACCGGTATGGGAATCGATCGCTTGTTGATGGCGCTCACCGGTTTGGG
AATCCGGGAAACGATACTGTTCCCAATTGTGCGTCCGGTCGCTCGCTGA

Protein sequence :
MSTPNTPSSGRSAGSAPAGQSSRPAQDVDDVPEQMRIRREKRERLLEAGTEAYPVVVPRTHSLAEIRAAHPDLAPDTQTG
QQVGVAGRVIFLRNTGKLCFATLQEGDGTKLQAMISLNGVGADALAAWKADVDLGDFVFVHGEVIASRTGELSVMADSWS
MAAKSLRPLPVAHKEMNEESRVRQRYVDLIVRPEARQMARTRVAVVRALRNALERRGFLEVETPMLQTLHGGAAARPFVT
HSNALDMDLYLRIAPELFLKRCVVGGLEKVFEINRNFRNEGADSTHSPEFAMLETYEAYGTYDDSATMIRELIQEVAQEA
LGTQVVTLADGTEYDLRGEWATVEMYPSLSAALGEPVTPETTVEELRAIAARVGLEIPEEKGYGHGKLVEELWEHQYGDK
LYAPTFVRDFPVETSPLTRQHRSKPGVTEKWDLYVRGFELATGYSELVDPVIQRERFVDQARLAAQGDDEAMVLDEDFLA
AMEHGMPPTTGTGMGIDRLLMALTGLGIRETILFPIVRPVAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 5e-154 70