Gene Information

Name : serS (nfa1400)
Accession : YP_116346.1
Strain : Nocardia farcinica IFM 10152
Genome accession: NC_006361
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 127645 - 128907 bp
Length : 1263 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGACCTCCGACTCCTGCGGGAGGACCCCGACGCGGTGCGCGCCTCGCAGCGTGCCCGCGGCGAAGACCCCGCCCT
CGTCGACGCACTGCTCGAGGCGGACGCGGCCCGGCGTGCGGCGGTCGCCACCGCCGACAATCTGCGCGCCGAGCAGAAGG
CGATGAGCAAACAGATCGGGAAGGCGCCCAAGGAGGAGCGATCCGCGCTGCTGGCGCGCGCGCAGGAGCTGTCGGTCAAG
GTCAAGGAGGCCGAAGCCGCCCAGCACGCGGCCGACGCCGATCTCGACGCCGCGCATCGCGCGCTGTCGAACGTGGTGCT
GCCCGCCGTTCCGGCCGGTGGCGAGGACGACTACGTCGTGCTCGAGACCGTGGGCACCCCGCCGGAGTTCGACTTCGAGC
CCAAGGACCACCTCGAACTCGGCGAGGCGCTCGGCCTGATGGACATGGAGCGCGGCGCCAAGGTCTCCGGCTCGCGCTTC
TACTTCCTCACCGGCCACGGCGCGCTGCTGCAACTGGGCCTGCTGCAACTGGCCGCGCAGAAGGCGGTCGCCAACGGCTT
CACCATGATGATCCCGCCGGTGCTGGTGCGCCCGGAGGTGATGGCGGGCACCGGCTTCCTCGGCAGGCACGCCGCGGAGG
TCTACCACCTCGCCGACGACGACATGTACCTGGTCGGCACCTCGGAGGTGCCGCTGGCCGGCTACCACGCCGACGAGATC
CTCGACCTCAGCGCCGGTCCCAAGCGCTACGCGGGCTGGTCGTCGTGCTTCCGCCGCGAGGCGGGCAGCTACGGCAAGGA
CACCCGCGGCATCATCCGGGTGCATCAGTTCGACAAGGTCGAGATGTTCGTCTACACCACGCCCGACCAGGCCGAGGCCG
AGCACGAGCGGCTGCTGGCCTGGGAGCGGGAAATGCTGGCCGCGATCGAGGTGCCCTACCGCATCATCGACGTGGCGGCG
GGCGATCTGGGCAGCTCGGCGGCGCGCAAGTTCGACTGCGAAGCCTGGGTGCCGAGCCAGCAGACCTACCGGGAACTGAC
CTCGACCTCCAACTGCACCACCTTCCAGGCCCGCAGGCTGTCGGTGCGCTACCGCGACGAGAACGGGAAACCCCAGATCG
CGGCGACCCTGAACGGCACGCTGGCCACCACCCGGTGGATCGTGGCGATCCTGGAGAACCATCAGCGGGCCGACGGGTCG
GTGCGGGTGCCCGCCGCGCTGGTGCCGTTCGTCGGCACCGATGTGCTGCGGCCACCGGCCTGA

Protein sequence :
MIDLRLLREDPDAVRASQRARGEDPALVDALLEADAARRAAVATADNLRAEQKAMSKQIGKAPKEERSALLARAQELSVK
VKEAEAAQHAADADLDAAHRALSNVVLPAVPAGGEDDYVVLETVGTPPEFDFEPKDHLELGEALGLMDMERGAKVSGSRF
YFLTGHGALLQLGLLQLAAQKAVANGFTMMIPPVLVRPEVMAGTGFLGRHAAEVYHLADDDMYLVGTSEVPLAGYHADEI
LDLSAGPKRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEMFVYTTPDQAEAEHERLLAWEREMLAAIEVPYRIIDVAA
GDLGSSAARKFDCEAWVPSQQTYRELTSTSNCTTFQARRLSVRYRDENGKPQIAATLNGTLATTRWIVAILENHQRADGS
VRVPAALVPFVGTDVLRPPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-58 43