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Name : lysS (BPSL2281) Accession : YP_108877.1 Strain : Genome accession: NC_006350 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 2749035 - 2750561 bp Length : 1527 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGACCGAACCGACCCAACCGCAGGCCGCTGTCGCAGCGGACGAAAACCAGATCGTCGCGGAGCGCCGCGGCAAGCTGCG CGCGCTGCGCGACCAAGGCATCGCCTATCCGAACGACTTCCAGCCGACGCACCACGCGGCCGGTCTGCAGACCGAATACG CGGACGCCGACAAGGAAGCGCTCGACGCGAAGGCGCTCGACGTCGCGGTCGCCGGCCGGATGATGCTCAAGCGCGTGATG GGCAAGGCGAGCTTCGCGACGGTGCAGGACGGTTCGGGTCAAATCCAGTTCTTCGTGACGCCCGCCGATGTCGGCGCCGA AACGTACGACGCGTTCAAGAAGTGGGACCTGGGCGACATCGTCGCCGCGCGCGGCGTGCTGTTTCGCACGAACAAGGGCG AGCTGTCGGTGAAGTGCACGGAGCTGCGGCTGCTCGCGAAGGCGCTGCGTCCGCTGCCCGACAAGTTCCACGGCCTCGCC GACCAGGAAACGCGCTATCGCCAGCGCTACGTCGATCTGATCGTCACGCCCGAGACGCGCGCGACGTTCCGCGCGCGCAC GAAGGCGATCGCGTCGATCCGCAAGTTCATGAGCGACGCCGATTTCATGGAAGTCGAGACGCCGATGCTGCACCCGATCC CGGGCGGCGCGGCCGCGAAGCCGTTCGTCACGCATCACAATGCGCTCGACATGCAAATGTTCCTGCGCATCGCGCCCGAG CTTTACCTGAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAGATCAACCGCAACTTCCGGAACGAAGGCGTGTC GCCGCGCCACAATCCGGAATTCACGATGATGGAGTTCTACGCCGCGTACACCGATTACCGCTGGCTGATGGACTTCACCG AGCGGCTGATCCGCCAGGCGGCCGTCGACGCGCTCGGCACCGCGACGATCCGGTACCAGGGCCGCGAGCTCGATCTCGCC AAGCCGTTCCATCGCCTGACGATCACGCAGGCGATCCAGAAATACGCACCGAACTACACGGACGGTCAGTTGTCGGACGA CGCTTTCCTGCGCGGCGAACTCAAGCGGCTGGGCGTCGACGTCACGCAGCCGGCGTTCCTGAACGCCGGCATCGGCGCGC TGCAGCTCGCGCTCTTCGAGGAAACCGCTGAAGCGCAGCTGTGGGAACCGACCTTCATCATCGACTACCCGATCGAGGTG TCGCCGCTCGCGCGCGAATCGGACACGGTGGCGGGCATCACCGAGCGCTTCGAGCTGTTCGTCACCGGCCGCGAAATCGC GAACGGCTTCTCGGAACTGAACGACCCCGAAGACCAGGCCGCGCGCTTCAGGAAGCAGGTCGAGCAGAAGGACGCGGGCG ACGAAGAGGCGATGTTCTTCGACGCCGACTACATCCGCGCGCTCGAATACGGAATGCCGCCGACAGGCGGCTGCGGGATC GGCATCGACCGGCTCGTGATGCTGCTGACCGACAGCCCGACGATTCGCGACGTGCTGCTGTTCCCGCACCTGCGCCGCGA AGACTGA Protein sequence : MTEPTQPQAAVAADENQIVAERRGKLRALRDQGIAYPNDFQPTHHAAGLQTEYADADKEALDAKALDVAVAGRMMLKRVM GKASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVKCTELRLLAKALRPLPDKFHGLA DQETRYRQRYVDLIVTPETRATFRARTKAIASIRKFMSDADFMEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPE LYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTERLIRQAAVDALGTATIRYQGRELDLA KPFHRLTITQAIQKYAPNYTDGQLSDDAFLRGELKRLGVDVTQPAFLNAGIGALQLALFEETAEAQLWEPTFIIDYPIEV SPLARESDTVAGITERFELFVTGREIANGFSELNDPEDQAARFRKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGI GIDRLVMLLTDSPTIRDVLLFPHLRRED |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 9e-126 | 55 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 9e-75 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_108877.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 5e-126 | 55 |
