Gene Information

Name : leuS (BF4586)
Accession : YP_101857.1
Strain : Bacteroides fragilis YCH46
Genome accession: NC_006347
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 5270961 - 5273792 bp
Length : 2832 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAATATAATTTCAGGGAGATCGAAAAGAAATGGCAGAAAATTTGGGTAGACAACCATACCTACCAGGTAAATGAAGA
TGCATCCAAACAAAAATTCTATGTACTCAATATGTTCCCCTATCCTTCGGGTGCCGGACTGCACGTAGGTCATCCCCTGG
GATATATTGCCTCAGACATTTATGCGCGCTATAAACGCCTGCAAGGATTTAACGTATTGAACCCGATGGGATATGATGCT
TACGGACTGCCGGCCGAACAATATGCTATTCAAACCGGACAGCACCCTGCAATTACCACTGTTAATAACATCAACCGCTA
TCGTGAACAATTAGATAAGATTGGTTTCTCTTTCGACTGGAATCGTGAAATTCGCACTTGCGATCCGGAATATTATCATT
GGACCCAATGGGCATTTATCAAAATGTTCAACAGCTATTATTGCAATGATGAAAAACAGGCACGTCCCATCGAAGAGTTA
ATAGAAGCTTTTAGTACCAACGGAACACAAGGTATGAACGTAGCCTGTGGCGAAGAAATGGACTTCACTGCCGACGAATG
GAATGCTAAAAGCGAAAAAGAACAACAGGAAATCCTCATGAACTACCGTATAGCCTATTTGGGCAATACAATGGTAAACT
GGTGTCCGGCTTTGGGTACCGTACTTGCCAATGATGAAGTAGTTGACGGTGTTTCCGAAAGAGGCGGTTATCCCGTTATT
CAAAAAGTGATGCGTCAGTGGTGCCTGCGCGTATCCGCTTATGCACAGCGTTTGCTCGACGGACTTGAAACCGTAGAATG
GACCGACTCGCTGAAAGAGACTCAACGCAACTGGATAGGACGCAGCGAAGGTGCTGAAATGAACTTTAAAGTGAAAGATT
CGGATATTGAATTTACTATCTTTACAACCCGTGCCGACACGGTATTTGGAGTTACTTTCATGGTGCTTGCCCCGGAAAGT
GAATTGGTAGCCAAGTTGACCACTCCGGAACAAAAAGCCGAAGTAGATGCTTATCTGGACCGTACCAAAAAACGTACCGA
ACGCGAACGTATTGCCGACCGTAGCGTAAGCGGCGTATTCTCCGGAAGCTATGCCATTAACCCATTGACCAACGAACCCA
TACCGGTATGGATTAGCGATTATGTATTAGCAGGTTACGGTACAGGTGCCATCATGGCTGTTCCTGCACACGATAGCCGT
GACTATGCTTTTGCCAAACATTTCAATCTGGAAATCCGTCCGCTGATCGAAGGTTGCGACGTCAGTGAAGAAAGCTTCGA
CGCCAAAGAAGGCATCATGATGAATTCTCCCCGTCCGGGAGCTCCCGAAGGCGGACTCGTATTGAACGGATTGACCGTAA
AAGAAGCAATCGCCAAAACTAAAGAATATATCAAGGCAACCGGATTAGGCCGTGTGAAAGTCAATTTCCGTCTGCGTGAT
GCAATTTTCTCACGTCAGCGCTATTGGGGCGAACCATTCCCGGTTTACTACAAAGACGGAATGCCTTACATGATTGATGA
AAGTTGCCTCCCGCTGGAATTGCCGGAAGTAGCCAAATTCCTTCCTACCGAAACCGGTGAACCACCATTGGGACATGCCA
CTAAATGGGCATGGGACACTGTCAACAAATGCGTGACTGACAATGAAAACATTGATAATAGAACCATTTTCCCACTGGAA
CTGAATACGATGCCGGGATTTGCCGGTTCATCCGCCTATTATCTGCGCTATATGGATCCGCGCAATCACGAAGCTCTCGT
TTCTCCCGCCGTGGATCAGTACTGGAAAAATGTAGACTTATATGTAGGAGGTACGGAACATGCTACCGGACACTTGATTT
ATTCACGTTTCTGGAATAAGTTCCTGCACGATTGGGGTATCTCCGTAGCCGAAGAGCCTTTCCAGAAACTTGTAAATCAG
GGAATGATACAAGGACGAAGTAACTTTGTCTACCGTATCAAGGATACCAATACTTTCGTATCTCTCAATCTGAAAGATCA
ATATGAAGTTACTCCTATCCACGTAGATGTCAACATCGTATCCAACGATATCCTCGACCTGGAAGCTTTCAAGGCTTGGA
GACCCGAATACGAAACTGCCGAATTTATTCTGGAAGACGGCAAGTATATCTGTGGATGGGCTGTTGAAAAGATGAGTAAA
TCTATGTTCAATGTGGTAAATCCGGATATGATTGTTGAAAAATACGGTGCCGATACACTCCGTATGTACGAAATGTTCCT
CGGACCGGTTGAACAGTCCAAACCTTGGGATACGAACGGAATAGATGGCGTACATCGTTTCATCAAAAAATTCTGGTCAT
TGTTCTATGACAGAAACGGCGAATATCTGGTAAAAGACGAACCGGCTACCAAAGAAGAACTAAAAGCACTCCATAAGTTG
ATTAAGAAAGTAACCGGTGATATCGAACAGTTCTCTTACAACACTTCAGTAAGTGCTTTCATGATCTGTGTCAATGAACT
TTCAAGTCTGAAATGCAATAAAAAAGAGGTATTGGAGCAACTCATCGTAGTTCTTGCACCTTTTGCTCCGCATGTATGCG
AAGAGTTATGGGATACACTGGGAAACACCACCTCTGTATGCGATGCACAATGGCCGACTTTCAACGAGCAATACCTGGTA
GAAGATACGGTTAATTACACCATTTCTTTCAATGGTAAAGCACGTTTCAATATGGAATTTCCGGCTGATGCCGCCAGCGA
TGCGATTCAAGCCACTGTACTTGCCGACGAACGCTCGTTAAAATGGACAGAAGGCAAAACACCGAAGAAAGTTATCGTAG
TCCCGAAGAAGATTGTTAACATTGTTATTTAA

Protein sequence :
MEYNFREIEKKWQKIWVDNHTYQVNEDASKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYARYKRLQGFNVLNPMGYDA
YGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNREIRTCDPEYYHWTQWAFIKMFNSYYCNDEKQARPIEEL
IEAFSTNGTQGMNVACGEEMDFTADEWNAKSEKEQQEILMNYRIAYLGNTMVNWCPALGTVLANDEVVDGVSERGGYPVI
QKVMRQWCLRVSAYAQRLLDGLETVEWTDSLKETQRNWIGRSEGAEMNFKVKDSDIEFTIFTTRADTVFGVTFMVLAPES
ELVAKLTTPEQKAEVDAYLDRTKKRTERERIADRSVSGVFSGSYAINPLTNEPIPVWISDYVLAGYGTGAIMAVPAHDSR
DYAFAKHFNLEIRPLIEGCDVSEESFDAKEGIMMNSPRPGAPEGGLVLNGLTVKEAIAKTKEYIKATGLGRVKVNFRLRD
AIFSRQRYWGEPFPVYYKDGMPYMIDESCLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVTDNENIDNRTIFPLE
LNTMPGFAGSSAYYLRYMDPRNHEALVSPAVDQYWKNVDLYVGGTEHATGHLIYSRFWNKFLHDWGISVAEEPFQKLVNQ
GMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNIVSNDILDLEAFKAWRPEYETAEFILEDGKYICGWAVEKMSK
SMFNVVNPDMIVEKYGADTLRMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWSLFYDRNGEYLVKDEPATKEELKALHKL
IKKVTGDIEQFSYNTSVSAFMICVNELSSLKCNKKEVLEQLIVVLAPFAPHVCEELWDTLGNTTSVCDAQWPTFNEQYLV
EDTVNYTISFNGKARFNMEFPADAASDAIQATVLADERSLKWTEGKTPKKVIVVPKKIVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-128 42