Gene Information

Name : BF4482 (BF4482)
Accession : YP_101753.1
Strain : Bacteroides fragilis YCH46
Genome accession: NC_006347
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 5142547 - 5144004 bp
Length : 1458 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTTGCTGAAACAGACTAAAATCGTAGCTTCCATCTCAGACAGACGTTGCGATGTAGATTTTATAAAAGAGTTGTTTGA
TGCAGGGATGAATGTGGTTCGTATGAACACAGCCCACGCCAGTCGTGAAGGTTTTGAGGCGTTGATTGCCAATGTGCGTG
CCGTATCCAATCGCATTGCCATCCTTATGGATACCAAGGGACCGGAAGTGCGTACCACTGCCAATGCGGACCCCATACTT
TATCAGATCGGTGAGAAAGTTAAAATCGTAGGAGATCCCGATCGTGAGACTACCCGTGAATGCATTGCCGTTTCATATCC
GAATTTTGTGCATGACCTGAATGTAGGGGGGACTATTTTGATAGATGATGGTGACCTTGAATTGCGAGTTATTGATAAAA
CAACCGAATACTTACTTTGTGAAGTCCAGAACGAGGCAACTTTGGGGAGCCGTAAGAGTGTAAACGTTCCGGGTGTTCGT
ATCAATCTCCCCTCTTTAACCGAGAAAGATCGTAATAACATCCTTTATGCCATAGAGAAAGATATCGATTTCATTGCTCA
TTCTTTTGTGCGTAACCGCCAGGATGTGCTTGATATCCGTGGAATACTGGACGCTCACAATAGTGATATCCGCATTATTG
CCAAGATCGAAAATCAGGAAGGTGTCGATAACATTGATGAGATCCTGGAAGTTGCCGATGGAGTAATGGTAGCTCGTGGT
GACTTGGGTATTGAAGTACCGCAGGAACGTATTCCGGGAATTCAGCGTATGTTGATACGCAAATGTATCCTTGCCAAAAA
ACCGGTAATCGTGGCAACACAAATGTTGCATACGATGATTAATAATCCACGTCCGACTCGTGCGGAAGTAACCGATATTG
CCAATGCAATCTATTATCGTACAGACGCTTTGATGTTGAGTGGTGAGACTGCCTATGGCAAATATCCTGTAGAGGCCGTG
AAAACGATGACTAAGATTGCTGCACAGGCTGAGAAGGACAAGTTGGAGGAGAATGACATTCGCATTCCTTTGGACGAAAA
CAGTAATGATGTCACAGCTTTCCTTGCTAAACAAGCTGTAAAAGCAACTACTAAGCTAAAGATACGTGCCATCATTACGG
ATAGCTATCAGGGGCGTACTGCACGCAATTTAGCAGCTTTCCGTGGTAAATATCCGGTACTTGCAATTTGTTATAAGGAG
AAGACTATGCGTCACCTTGCACTTTCTTATGGTGTGGAAGCGATTTATATGCCTGAACTTGCCAACGGGCAGGAGTACTA
TTTTGCAGCTCTGCGCCGTTTGTTGAAAGAAGGACGTTTGCATCCAACTGATATGGTGGGTTATCTGAGTAGCGGTAAAG
CCGGAACGCAGACTTCTTTCCTCGAAATCAATGTCGTGGAAGATGCTTTGAAGCATGCCGGTGATAGTGTGTTGCCTAAT
AGCAACCGTTATTTATAA

Protein sequence :
MLLKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNRIAILMDTKGPEVRTTANADPIL
YQIGEKVKIVGDPDRETTRECIAVSYPNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVR
INLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGILDAHNSDIRIIAKIENQEGVDNIDEILEVADGVMVARG
DLGIEVPQERIPGIQRMLIRKCILAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAV
KTMTKIAAQAEKDKLEENDIRIPLDENSNDVTAFLAKQAVKATTKLKIRAIITDSYQGRTARNLAAFRGKYPVLAICYKE
KTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLHPTDMVGYLSSGKAGTQTSFLEINVVEDALKHAGDSVLPN
SNRYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-76 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BF4482 YP_101753.1 pyruvate kinase VFG0479 Protein 8e-76 41