Gene Information

Name : BF1205 (BF1205)
Accession : YP_098489.1
Strain : Bacteroides fragilis YCH46
Genome accession: NC_006347
Putative virulence/resistance : Virulence
Product : endopeptidase Clp ATP-binding subunit B
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1437523 - 1440111 bp
Length : 2589 bp
Strand : -
Note : similar to gp:AE016945_241 [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 862 aa, BLASTP E(): 0.0

DNA sequence :
ATGAACTTTAACAATTTTACCATTAAATCTCAGGAAGCTGTACAAGAGGCTATTAACCTGGCACAAAGTCGGGGACAACA
AGCCATCGAAACGGCTCATATCCTGTACGGAGTGATGAAGGTAGGCGAAAATGTGACTAACTTTATCTTTCAGAAGTTAG
GACTGAACGGACAACAAATCTCCCTCGTACTCGATAAGCAGATCGACTCTTTCCCAAAAGTTTCCGGCGGAGAACCTTAC
TTGAGTAGGGAAGCGAACGAAGTCTTTCAAAAAGCAACACAGTACTCCAAGGAGATGGGCGATGAGTTTGTTTCATTGGA
ACATCTTTTGCTGGCTTTACTGACAGTAAAGAGCACGGTGTCTACCATCCTGAAAGATGCAGGAATGACCGAAAAAGAAT
TGCGTGGTGCCATCAGTGAATTGAGAAAAGGAGAAAAGGTGACCTCTCAGTCCAGTGAAGATAATTACCAGTCACTGGAA
AAATATGCCATTAATTTAAATGAAGCAGCCCGTAGCGGTAAACTCGACCCAGTGATCGGACGTGATGAAGAAATCCGACG
GGTACTTCAGATTTTAAGTCGACGTACAAAAAACAATCCTATATTAATAGGTGAACCGGGTACCGGTAAAACAGCTATTG
TTGAGGGATTGGCACACCGTATTCTTCGGGGTGATGTTCCTGAAAACCTGAAAAATAAACAGGTATACTCACTTGATATG
GGCGCACTCGTTGCAGGAGCTAAATATAAAGGAGAATTTGAGGAACGACTGAAATCGGTAGTGAATGAGGTGAAGAAATC
AGAAGGTAATATCATATTATTCATTGATGAAATCCATACTTTGGTAGGGGCAGGAAAAGGAGAAGGTGCTATGGACGCAG
CTAATATTCTGAAACCTGCACTTGCCCGTGGAGAACTACGCTCTATCGGTGCTACCACTCTCGACGAATATCAGAAATAT
TTTGAAAAAGATAAAGCTTTGGAACGTCGTTTCCAAATAGTACAGGTAGATGAACCGGACAATCTGAGCACAATATCTAT
CTTACGTGGATTAAAAGAACGGTATGAAAATCACCATCACGTACGTATCAAAGATGATGCAATCATTGCTGCCGTAGAAT
TAAGCAGCCGGTACATCACTGACCGTTTTTTACCCGATAAAGCAATTGACCTGATGGACGAAGCTGCCGCAAAACTTCGC
ATGGAGGTGGATTCTGTCCCTGAAGGATTAGATGAAATCTCACGAAAGATTAAACAGCTGGAGATTGAGCGAGAAGCTAT
AAAACGGGAAAATGATGAACCGAAATTACAGACAATCGGCAAAGAATTGGCTGAATTGAAAGAACAGGAAAAATCATATA
AAGCAAAATGGCAAAGCGAGAAAAGCCTGATGGATATAATCCAGCAGAACAAAGTTGAAATAGAAAATCTTAAATTCGAA
GCTGACAAGGCAGAACGTGAGGGAAACTATGGCAAAGTTGCAGAGATTCGCTATGGCAAATTGCAGGAACTGCATAAGGA
AATTGAAGATACCCAGAAAAAATTGCACGAAATGCAAGGGGATACAGCCATGATAAAAGAAGAGGTGGATGCTGAAGACA
TCGCTGACGTAGTATCCCGCTGGACCGGAATTCCTGTAAGCAAAATGATGCAGAGTGAAAAGGACAAATTGCTCCACCTT
GAAGAAGAATTACATCAGCGTGTTATCGGACAAGACGAGGCTATTGCAGCTGTGTCTGATGCTGTACGCCGCAGCCGTGC
AGGCTTACAGGATCCCAAACGACCTATTGGTTCCTTCATCTTCCTGGGCACTACAGGAGTTGGTAAAACCGAACTTGCCA
AAGCGCTTGCCGAATTTCTGTTTGACGATGAAACGATGATGACCCGTATCGACATGAGCGAATACCAGGAGAAGCACAGC
GTTTCGCGTTTAGTTGGAGCGCCTCCGGGATATGTAGGATATGACGAAGGCGGACAATTGACAGAGGCGATCCGTCGCAA
ACCCTATTCTGTAGTATTGTTTGATGAAATCGAGAAAGCACATCCGGATGTATTTAATATCTTGTTGCAGGTACTCGATG
ACGGACGGTTGACAGATAACAAAGGCCGTGTGGTAAACTTTAAAAATACAATCATCATCATGACCTCTAATATGGGTAGC
AGCTACATACAGAGCCAGATGGAAAAACTGAACGGCGCCAACAACGAGGAAGTAGTGGAAGAAACCAAGAAAGAGGTAAT
GAACATGTTAAAGAAAACCATCCGTCCGGAATTCCTAAACCGTATCGATGAGACTATCATGTTCCTGCCATTAACAGAAA
AAGACATAAAACAGATTGTCTTGTTACAGATTAAGAGCGTACAAAAGATGCTTGCCGGTAATGGAGTAGAACTAGAACTG
ACAGATGCGGCTTTGGATTTCCTCTCACAGGTCGGCTATGATCCGGAATTCGGTGCACGTCCTGTAAAAAGGGCTATTCA
GAGATATTTACTCAACGATCTATCGAAAAAATTATTGGCACAGGAAGTAGACCGTAGTAAAGCAATCATTGTAGATGCAC
AAGGAGACGGGTTAGTTTTCCGTAACTAA

Protein sequence :
MNFNNFTIKSQEAVQEAINLAQSRGQQAIETAHILYGVMKVGENVTNFIFQKLGLNGQQISLVLDKQIDSFPKVSGGEPY
LSREANEVFQKATQYSKEMGDEFVSLEHLLLALLTVKSTVSTILKDAGMTEKELRGAISELRKGEKVTSQSSEDNYQSLE
KYAINLNEAARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRILRGDVPENLKNKQVYSLDM
GALVAGAKYKGEFEERLKSVVNEVKKSEGNIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQIVQVDEPDNLSTISILRGLKERYENHHHVRIKDDAIIAAVELSSRYITDRFLPDKAIDLMDEAAAKLR
MEVDSVPEGLDEISRKIKQLEIEREAIKRENDEPKLQTIGKELAELKEQEKSYKAKWQSEKSLMDIIQQNKVEIENLKFE
ADKAEREGNYGKVAEIRYGKLQELHKEIEDTQKKLHEMQGDTAMIKEEVDAEDIADVVSRWTGIPVSKMMQSEKDKLLHL
EEELHQRVIGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEFLFDDETMMTRIDMSEYQEKHS
VSRLVGAPPGYVGYDEGGQLTEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNMGS
SYIQSQMEKLNGANNEEVVEETKKEVMNMLKKTIRPEFLNRIDETIMFLPLTEKDIKQIVLLQIKSVQKMLAGNGVELEL
TDAALDFLSQVGYDPEFGARPVKRAIQRYLLNDLSKKLLAQEVDRSKAIIVDAQGDGLVFRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-157 45
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-100 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 4e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BF1205 YP_098489.1 endopeptidase Clp ATP-binding subunit B VFG2084 Protein 8e-109 41