Gene Information

Name : clpC (BLi00104)
Accession : YP_006711556.1
Strain : Bacillus licheniformis DSM 13
Genome accession: NC_006322
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ClpC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 102347 - 104779 bp
Length : 2433 bp
Strand : +
Note : ''ATPase subunit of the ClpC-ClpP protease, involved in competence development, heat shock regulation, motility, sporulation, protein quality control, biofilm formation''

DNA sequence :
ATGATGTTTGGAAGATTCACAGAAAGAGCACAAAAAGTATTGGCGCTTGCTCAAGAAGAAGCTCTGCGTCTGGGCCATAA
TAACATTGGAACAGAACATATTCTCCTCGGCCTTGTCCGCGAGGGAGAAGGAATTGCTGCGAAAGCGCTGCAGGCGTTAG
GACTCAGCCCTGACAAGATTCAAAAAGAAGTTGAAAGCCTCATCGGCCGCGGACAAGAAATGTCACAATCGATCCATTAC
ACACCGAGAGCCAAGAAAGTGACCGAATTGGCGATGGATGAAGCGAGAAAGCTTGGCCACTCCTACGTTGGAACTGAACA
CATCCTCCTTGGCTTAATCCGCGAAGGGGAAGGTGTTGCGGCAAGGGTGCTGAATAATTTAGGCGTCAGCTTAAACAAAG
CGAGACAGCAAGTATTGCAGCTGTTGGGCAGCAATGAGAGCGGAGGCGCTGCTTCAGGCGCCAACAGTAGCGCCAACACA
CCAACTTTAGACAGTCTTGCCCGGGATCTCACGGCGATTGCAAAAGAAGACAGCCTTGATCCCGTGATCGGCAGAAGCAA
AGAAATTCAACGCGTGATTGAAGTGTTGAGCCGCAGAACGAAAAATAACCCTGTGTTAATCGGGGAGCCTGGTGTCGGTA
AGACTGCGATTGCCGAAGGCCTGGCCCAGCAGATCATCAATAACGAAGTACCGGAGATTTTACGCGACAAGCGCGTCATG
ACACTTGATATGGGAACGGTTGTCGCCGGCACGAAATATCGCGGTGAATTTGAAGACCGCCTGAAAAAAGTGATGGACGA
AATTCGTCAAGCGGGAAATATCATCCTCTTCATCGATGAGCTGCATACTCTCATCGGAGCCGGAGGAGCGGAAGGGGCCA
TCGATGCCTCCAATATCCTTAAACCGTCGCTGGCGCGCGGAGAGCTGCAATGCATCGGGGCGACAACCCTTGATGAATAC
CGCAAATACATTGAAAAAGATGCTGCACTAGAACGGCGTTTTCAGCCGATTCAGGTTGACCAGCCGTCTCCTGAAGAAAG
CATTCAAATATTGAAAGGGCTCAGAGACCGCTATGAAGCCCATCACCGCGTATCGATTACGGATGAAGCGATCGAAGCGG
CAGTAAAGCTGTCAGACCGCTACATTTCGGACCGTTTTCTGCCTGACAAGGCGATCGACTTAATCGATGAAGCCGGCTCA
AAGGTTAGACTGCGTTCATTCACAACGCCTCCTAACTTAAAAGAGCTTGAACAAAAGCTTGATGAGGTAAGGAAAGAAAA
AGATGCCGCTGTTCAAAGCCAGGAATTCGAAAAAGCAGCGTCTTTACGTGATACGGAGCAGCGCTTGCGTGAACAGGTCG
AAGAAACCAAGAAAACCTGGAAAGAAAAGCAAGGTCAAGAAAATTCCGAAGTGACCGTCGACGATATTGCAATGGTTGTA
TCAAGCTGGACCGGAGTGCCGGTTTCCAAAATTGCGCAGACCGAAACAGACAAATTGCTGAACATGGAGAGCATTCTTCA
TTCCCGCGTTATCGGCCAGGATGAGGCTGTCGTTGCAGTTGCAAAAGCAGTCAGACGCGCGCGTGCCGGCTTAAAAGATC
CAAAACGTCCTATCGGTTCGTTTATTTTCCTTGGCCCAACAGGCGTAGGGAAAACGGAGCTTGCCCGTGCACTTGCCGAG
TCCATTTTCGGCGATGAAGAAGCAATGATTCGCATCGATATGTCCGAGTACATGGAAAAACATTCAACATCAAGACTCGT
CGGTTCACCTCCTGGATATGTCGGCTATGATGAAGGCGGACAGCTCACTGAAAAAGTGAGAAGAAAACCGTATTCCGTCG
TCTTGCTTGATGAAATCGAGAAAGCTCACCCAGATGTCTTCAATATTTTGCTGCAGGTGCTTGAAGACGGCCGCCTGACT
GATTCAAAAGGGCGCACGGTTGACTTTAGGAATACGATTTTGATCATGACATCAAACGTCGGTGCGAGCGAACTGAGAAG
AAATAAATACGTCGGGTTTAATGTCCAGGATGAAACCCAGAATTATAAAGATATGAAAGACAAAGTCATGGGTGAACTAA
AACGCGCCTTTAGACCTGAATTTATCAACCGGATTGATGAGATCATCGTCTTCCACTCTTTGGAGAAAAAACATTTGAAA
GATATTGTATCCCTCATGTCAGACCAATTGACCAAGCGTCTGAAAGAACAGGATCTTTCAATTGAGCTGACTGAAGCGGC
TAAAGAAAAAATCGCCGATGAAGGCGTGGATCTCGAATACGGAGCGCGTCCTCTCAGAAGAGCAATCCAAAAACACGTGG
AAGACCGGCTGTCAGAAGAGCTCCTAAAAGGCCATATTCAAAAAGGCCAGCATATTGTTTTGGATGTAGAAGACGGAGAA
TTTGTCGTAAAAACCGAAGCTAAAACGAACTAA

Protein sequence :
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKIQKEVESLIGRGQEMSQSIHY
TPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEELLKGHIQKGQHIVLDVEDGE
FVVKTEAKTN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_006711556.1 ATP-dependent Clp protease ClpC VFG0079 Protein 0.0 79
clpC YP_006711556.1 ATP-dependent Clp protease ClpC VFG0080 Protein 1e-150 54