Gene Information

Name : kdsB (MS0935)
Accession : YP_088127.1
Strain : Mannheimia succiniciproducens MBEL55E
Genome accession: NC_006300
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 912861 - 913640 bp
Length : 780 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACAAATTTTACTGTAATTATTCCGGCTCGTTTTGCTTCAAGCCGTTTACCGGGTAAGCCCTTAGCGGATATTGCCGG
CAAACCCATGATTATTCATGTGTTGGAAAAAGCGCGGTTATCGGGGGCGACAAGAGTAGTTGTGGCGACCGATAATGAAG
AAGTAAAGCAAGCCGTCGAACAGTTTGGCGGCGAAGTATGTATGACTTCGGCAAAACACAATTCCGGCACCGAACGTTTA
GCCGAGGTGGTGGAAACGCTTAATATTCCCGATGATGAAATTATTGTGAATATTCAGGGCGACGAACCTTTGATTCCGCC
GGTTATCGTTTCGCAAGTTGCTGAAAATTTATGTAAATTTAAAGTAAATATGGCAAGTTTGGCAGTGAAAATTCATGAAT
CGGCGGAACTTTTTAACCCTAACGCCGTCAAAGTGCTGACCGATAAAGACGGCTATGTGTTATATTTCTCCCGAGCGCCG
ATTCCCTGGAATAGAGACGCCTTTGCAAGGCTCAACTCCGGCGAGTTAAAGCAGGAAGAATTAGACTTGGCGGATCATTA
TTTACGTCATATCGGTATTTATGCATATCGCGCGGGCTTTATTAAACAATATGTGCAATGGGAACCGAGCGCCTTAGAGC
AAATCGAAAGCCTGGAACAGCTTAGAGTGCTTTGGTACGGGGAAAAAATTCACGTGGAGTTAGCGAAAGAAATTCCGGCT
GTTGGCGTCGATACCGCAGAAGATCTTGAGAAAGTAAGAGCTATTTTATCAAATTTTTAA

Protein sequence :
MTNFTVIIPARFASSRLPGKPLADIAGKPMIIHVLEKARLSGATRVVVATDNEEVKQAVEQFGGEVCMTSAKHNSGTERL
AEVVETLNIPDDEIIVNIQGDEPLIPPVIVSQVAENLCKFKVNMASLAVKIHESAELFNPNAVKVLTDKDGYVLYFSRAP
IPWNRDAFARLNSGELKQEELDLADHYLRHIGIYAYRAGFIKQYVQWEPSALEQIESLEQLRVLWYGEKIHVELAKEIPA
VGVDTAEDLEKVRAILSNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-37 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-37 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-37 42