Gene Information

Name : guaA (MS0772)
Accession : YP_087964.1
Strain : Mannheimia succiniciproducens MBEL55E
Genome accession: NC_006300
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 744195 - 745766 bp
Length : 1572 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACAACATTCACAACCATAAAATCCTAATCCTCGACTTCGGTTCCCAATATACCCAGCTGATCGCGCGTCGCGTGCG
TGAAATCGGGGTTTACTGCGAACTTTGGGCGTGGGACGTAACGGAACAACAAATCCGTGAATTTAATCCGACCGGGATTA
TTCTTTCCGGCGGTCCGGAAAGCACCACCGAAGACAACAGCCCGCGTGCGCCGGAATATGTATTTAACGCAGGCGTGCCG
GTGTTAGGCATTTGCTACGGTATGCAAACCATGGCAATGCAGCTCGGCGGGCTGACCGAACCGTCCAGCCACCGTGAATT
CGGCTATGCTTCCGTTTCTCTCGAAAATTCCACCGCACTTTTTGCTCAGCTGAATGATGATTTAAATTCCTCCCTGCCAA
AACTGGACGTCTGGATGAGCCACGGCGATAAAGTAACCCGTTTGCCGGAAGGTTTTCAGCTGACCGGTACCACGTCGACT
TGCCCAATCGCCGCCATGTCTGACGAAAGCCGTCATTTCTACGGCGTGCAGTTCCACCCTGAAGTTACCCACACCAAAAG
CGGTTTGGCGTTATTAACCAACTTTGTGGTGAATATTTGCGGATGTACAACCAACTGGACGCCGGAAAACATCATTGAAG
ATGCGGTAGCTCGCATTAAAGCGCAAGTGGGCGACGATGAAGTGATTTTAGGCTTATCCGGCGGTGTGGATTCTTCGGTA
ACCGCATTATTATTACACCGCGCTATCGGCAAAAATTTACACTGTGTGTTCGTGGATAACGGCTTATTACGTTTAAACGA
AGGCGATCAGGTAATGGAAATGTTCGGCGATAAATTCGGCTTGAATATTATCCGCGTCAACGCCGAAGATCGTTTCTTAG
ACGCATTGAAAGGCATTGACGAACCGGAATCCAAACGCAAAATGATCGGTAAAGTATTTGTGGATGTATTCGACGAAGAA
TCCCACAAACAAACCAGCGTTAAATGGCTGGCACAAGGCACCATTTATCCGGATGTGATTGAATCCGCCGCCAGCAAAAC
CGGCAAAGCACACGTGATTAAATCCCACCATAACGTAGGTGGTTTACCGGATTATATGAAGCTCGGCTTAGTGGAACCGC
TTCGCGAATTATTCAAAGATGAAGTACGTAAAATCGGCTTGGCCTTAGGCTTGCCTGCCGAAATGCTCAACCGCCACCCG
TTCCCGGGCCCGGGTTTAGGGGTGCGCGTATTGGGTGAAATCAAAAAAGAATACTGCGATTTACTGCGCAAAGCCGACGC
CATCTTTATCGAAGAACTTTACAACTCAGGCTGGTACTATAAAGTCAGCCAGGCGTTCACCGTATTCCTGCCGGTGAAAT
CCGTCGGCGTAATGGGCGACGGGCGTAAATACGACTGGGTGGTATCGTTACGTGCGGTAGAAACCATCGATTTTATGACC
GCACATTGGGCGCACTTGCCTTATGATCTATTAGGCAAAATCTCAAACCGTATCATCAACGAAGTGGACGGCATTTCCCG
CGTGGTGTATGACGTCAGCGGAAAACCTCCTGCGACGATTGAGTGGGAGTAG

Protein sequence :
MNNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEQQIREFNPTGIILSGGPESTTEDNSPRAPEYVFNAGVP
VLGICYGMQTMAMQLGGLTEPSSHREFGYASVSLENSTALFAQLNDDLNSSLPKLDVWMSHGDKVTRLPEGFQLTGTTST
CPIAAMSDESRHFYGVQFHPEVTHTKSGLALLTNFVVNICGCTTNWTPENIIEDAVARIKAQVGDDEVILGLSGGVDSSV
TALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPESKRKMIGKVFVDVFDEE
SHKQTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHP
FPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELYNSGWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMT
AHWAHLPYDLLGKISNRIINEVDGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-129 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-129 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-110 47