Gene Information

Name : leuS (MS0338)
Accession : YP_087530.1
Strain : Mannheimia succiniciproducens MBEL55E
Genome accession: NC_006300
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 316075 - 318657 bp
Length : 2583 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAACAATATCGTCCTGATTTGCTTGAACAAGAAGTGCAAAAATACTGGCAGAATAATCAGACCTTCAAAGCAGT
CAAAGACAGCAGCAAAGAAAAATATTATTGTTTATCAATGTTCCCTTATCCGTCCGGCCGCTTACATATGGGGCACGTAC
GTAACTATACGATTGCGGATGTGGTTTCCCGTTATCAACGAATGAACGGCAAAAACGTATTGCAACCGGTAGGTTGGGAC
GCTTTCGGTCTGCCTGCCGAAGGTGCGGCGGTAAAAAATAAAACCGCACCGGCAAAATGGACTTACGAAAATATCGATTA
CATGAAAAACCAGCTTAAAATGCTGGGTTTCTCATATGACTGGGATCGTGAAATCGCCACTTGCAAACCGGAATATTATA
AATGGGAACAATGGTTTTTCACCGAGCTTTATAAAAAAGGTCTGGTGTACAAAAAAACCTCTGTGGTGAACTGGTGTCCG
AATGACGAAACCGTACTTGCCAACGAACAGGTCCATGAAGGTTGCTGCTGGCGTTGCGACACGCCGGTAGAACAAAAAGA
AATTCCGCAATGGTTTATTAAAATTACCGATTATGCGGAACAGTTATTAAGCGGTTTAGATACCCTTCCCGAATGGCCGG
ATATGGTGAAAACCATGCAACGCAACTGGATTGGCCGTTCCGAAGGGGTGGAGATTACTTTCAAAATTGAAAACAGCGAC
GAAACCGTCGCGGTTTACACTACCCGTCCGGATACCTTCTACGGCGTATCTTACATGGCGGTGGCGGCCGGTCATCCGTT
AGCGGAAAAAGCGGCGCAAAATAACGCCGAATTAGCCCGTTTTATCCAGGAATGCAAAAATACCAAAGTAGCGGAAGCGG
AACTTGCCACCATGGAAAAAAAAGGCATGGCTACCGGCATTAATGCGATTCACCCGATTACCGGCAAACCGGTGCCGGTA
TGGGTAGCTAACTTTGTGCTAATGCATTACGGTACGGGCGCGGTGATGGCGGTGCCTGCTCATGATCAGCGTGACTTTGA
ATTCGCAACTAAATACGGCTTGCCTATTAAACAGGTTATTGCACCGATGAACGGTGAAGAAATCGATTTAACTAAAGCCG
CGTTTACCGAGCACGGTAAACTGGTGAATTCGGCGGAATTCGACGGTTTGGATTTTGAGGCCGCATTTAACGGTATTGCG
GATAAACTGGAAAAAATGGGCGTAGGTAAACGCCAGGTGAATTACCGCTTACGAGACTGGGGCGTATCCCGTCAACGTTA
CTGGGGCGCACCGATTCCGATGCTGACTCTGGAAAACGGCGATGTGGTGCCGGCGCCATTGCAGGATTTACCGATCGTTC
TTCCCGAAGACGTCGTAATGGACGGGGTAAAAAGCCCGATCAAAGCGGATCCGGACTGGGCGAAAACCAGTTATAACGGT
CAACCCGCATTAAAAGAAACCGATACCTTCGATACCTTTATGGAATCTTCCTGGTACTATGCGCGCTACACCAGCCCGCA
GTATCATGAAGGTATGCTGGATTCGGACGAGGCAAATTACTGGCTGCCCGTCGATCAATATATCGGCGGTATCGAACACG
CCACTATGCACTTGCTTTATTTCCGTTTCTTCCACAAATTGTTACGTGACGCAGGCTTGGTTTCTACCGATGAACCTACT
AAAAAATTACTTTGCCAAGGCATGGTATTAGCGGACGCTTTCTATTATACCAGCCCGACTAACGAACGTATTTGGGTGTC
GCCAACCAAAGTAATGCTGGAACGTGATGAAAAAGGTCGTATTCTGAAAGCGACGGATGATGAAGGTCACGAATTGGTTC
ACGCCGGTATGACCAAAATGTCAAAATCCAAAAACAACGGTATCGACCCGCAGGAAATGGTGGAAAAATACGGCGCCGAC
ACAGTACGTTTATTCATGATGTTTGCCTCCCCGGCAGAAATGACTTTGGAATGGCAGGAATCCGGCGTAGAAGGGGCTAA
ACGTTTCTTAGGGCGCTTATGGAATCTGGTATTTGAATATAATAAAAATCCGGTCAAAACGGCGCCGAATCCGACCGCAC
TTTCAAGTGCGCAAAAAGCGTTACGTCGTGATGTGCACAAAACCATTGCCAAAGTATCCGATGACATCGGCCGTCGCCAA
ACTTTCAACACGGCGATTGCGGCAATCATGGAATTAATGAATAAATTAACCCGTGCGCCGTTAACGGACGAACAGGATCG
CGCGGTGATGGGCGAAGCCTTGAGTGCGGTAGTGCGTATGCTGTATCCGATCACCCCGCATATCTGCTTCCAATTATGGA
AAGATCTAGGCAACGAGGATATCATCGATTTCGCTCCTTGGGTACAAGCGGACGAAGCAGCTATGATCGATGATGAAAAA
CTTGTTGTCGTGCAGGTAAACGGCAAGGTGCGCGGTAAAATTACGGTTCCGGCGGATATGGCGGAAGAAGAAATTAAACG
GGTCGCACTTGCGGAAGAAAACGTACAAAAATTCCTGGACGGTTTAAATATCGTTAAAGTGATTTATGTACCGGGTAAAT
TATTAAGCTTCGTAGCAAAATAA

Protein sequence :
MQEQYRPDLLEQEVQKYWQNNQTFKAVKDSSKEKYYCLSMFPYPSGRLHMGHVRNYTIADVVSRYQRMNGKNVLQPVGWD
AFGLPAEGAAVKNKTAPAKWTYENIDYMKNQLKMLGFSYDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSVVNWCP
NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLSGLDTLPEWPDMVKTMQRNWIGRSEGVEITFKIENSD
ETVAVYTTRPDTFYGVSYMAVAAGHPLAEKAAQNNAELARFIQECKNTKVAEAELATMEKKGMATGINAIHPITGKPVPV
WVANFVLMHYGTGAVMAVPAHDQRDFEFATKYGLPIKQVIAPMNGEEIDLTKAAFTEHGKLVNSAEFDGLDFEAAFNGIA
DKLEKMGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPLQDLPIVLPEDVVMDGVKSPIKADPDWAKTSYNG
QPALKETDTFDTFMESSWYYARYTSPQYHEGMLDSDEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGLVSTDEPT
KKLLCQGMVLADAFYYTSPTNERIWVSPTKVMLERDEKGRILKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRLWNLVFEYNKNPVKTAPNPTALSSAQKALRRDVHKTIAKVSDDIGRRQ
TFNTAIAAIMELMNKLTRAPLTDEQDRAVMGEALSAVVRMLYPITPHICFQLWKDLGNEDIIDFAPWVQADEAAMIDDEK
LVVVQVNGKVRGKITVPADMAEEEIKRVALAEENVQKFLDGLNIVKVIYVPGKLLSFVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-159 42