Gene Information

Name : clpA (MS1783)
Accession : YP_088975.1
Strain : Mannheimia succiniciproducens MBEL55E
Genome accession: NC_006300
Putative virulence/resistance : Virulence
Product : ClpA protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1776499 - 1779069 bp
Length : 2571 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATATCGAAAAATTTACCACAAAATTCCAACAGGCATTGGCCGAAGCGCAGTCATTAGCATTGGGAAAGGATAATCA
GTATATCGAGCCGGTTCATGTGCTGAGCGCCTTGATTAATCAGCAAGACGGTTCGGTGGCGCCGATTTTGACTTCCGCCG
GCGTGAATGTCGGGGCGTTGAAAGCGGAATTAAATAGTGAAATCAATAAATTGCCGCAGGTTTCCGGCAACGGCGGAGAT
GTGCAGATTTCCCGTCAGCTACTGAATTTATTGAATTTGTGCGACAAAATTGCACAGCGCAACAATGATAAATTTATTTC
ATCGGAATTATTTTTACTGGCCGCATTGGAAGAAAAAGGCAGCCTTGGCGATTTACTTAAAAAGTGCGGTGCAAAAAAAG
AAAGTTTAGAACAAGCGATTAAAACCATTCGTGGGGGACAAAGCGTGAATGATCAAAATGCGGAAGAAAGCCGTCAGGCT
CTTGAAAAATATACTATTGACTTAACCGAGCGGGCGGAAAGCGGCAAGCTTGACCCGGTAATCGGTCGTGATGAAGAAAT
TCGTCGTGCAATCCAGGTGTTACAACGCCGTACTAAAAATAACCCGGTGTTGATCGGTGAGCCCGGTGTAGGTAAAACCG
CTATCGTAGAAGGGTTGGCTCAACGTATCGTAAACGGCGAAGTGCCGGAAGGGTTGAAAGGCAAACGCGTACTTTCCCTT
GATATGGGTGCTTTAATTGCCGGGGCAAAATACCGCGGCGAATTTGAAGAACGTTTGAAAGCGGTATTAAAAGAGCTGGC
GCAAGAAGAAGGCAAGGTGATTTTGTTTATCGATGAAATTCACACCATGGTAGGAGCCGGTAAAACCGACGGCGCTATGG
ATGCGGGCAACTTATTAAAACCGTCTCTTGCCCGTGGCGAATTGCATTGCGTAGGGGCGACGACTTTAGACGAATATCGT
CAATACATCGAAAAAGACGCCGCACTTGAACGCCGTTTCCAAAAAGTATTTGTAGATGAACCGACAGTGGAAGACACCAT
TGCCATTCTGCGCGGTTTGAAAGAGCGTTATGAGCTGCACCATCACGTGCAAATTACCGACCCGGCAATCGTAGCGGCGG
CAACGCTTTCTCATCGCTATATTTCCGATCGTCAATTACCGGATAAAGCGATCGATCTGATTGATGAAGCGGCATCCAGC
ATTCGTATGGAAATCGATTCCAAACCTGAGCCGTTAGATCGTTTGGATCGTCGTATTATTCAATTAAAACTTGAACAACA
GGCATTGAAGAAAGAAGAAGACGAAGCAAGCCGCAAGCGTTTGGATATGCTTGAAAAAGAATTAAGCGAAAAAGAACGGG
AATATGCGGAGCTGGAAGAAGTCTGGAAAAGTGAAAAAGCCGCCCTTTCCGGCACGCAACATATTAAAGCCGAGCTTGAA
AGCGCCCGTACGCAAATGGAACAGGCACGTCGCGCCGGCGATTTGAATAAAATGTCCGAATTGCAATACGGCACGATTCC
GGCATTGGAAAAACAACTTGCAGCGGCAGATAGCGCAGAAGGCAAGGAAATGAGTCTGTTGCGTAACCGCGTGACCGACG
AAGAAATCGCCCAGGTACTTTCCCGCGCAACCGGTATTCCGGTTTCCCGCATGATGGAAGGCGAAAAAGAAAAATTATTG
CGTATGGAAGAGGAATTACATAAACGCGTTATCGGGCAAGGTGAAGCGGTGGAAGCGGTGGCGAACGCCATTCGTCGTAG
CCGTGCGGGGCTTTCCGACCCGAACCGTCCGATTGGCTCCTTCCTGTTTTTAGGGCCTACCGGGGTGGGTAAAACCGAGC
TTTGTAAAACGCTGGCGAACTTTATGTTCGACGATGAAAACGCCATGGTGCGTATCGATATGTCCGAGTTTATGGAAAAA
CACAGCGTATCCCGTTTGGTGGGGGCTCCTCCGGGTTATGTGGGTTATGAAGAAGGCGGTTATTTAACCGAAGCGGTGCG
CCGCCGTCCGTATTCCGTGATTTTATTGGATGAAGTGGAAAAAGCCCATCACGACGTATTCAATATTTTATTGCAAGTAT
TGGATGACGGGCGTTTAACCGACGGACAGGGCAGAACCGTAGATTTCCGCAATACCGTGGTGATTATGACATCAAACTTA
GGATCGGATTTAATTCAGGAAAATAAAGATCTTGGTTATGAAGGCATGAAGGAAATCGTGATGTCGGTGGTCGGCCAACA
TTTCCGTCCGGAATTCATCAACCGTATTGATGAAACCGTGGTATTCCATCCGTTAGCGAAAGAAAACATCAAGGCGATTG
CACAAATCCAATTAGCCCGCTTAACCAAACGTATGGAGCAACACGGTTATGCAATTAACTTTAGCGAAACCTTGTTGGAT
TTTATCAGCGAAGTCGGTTACGATCCGGTTTACGGAGCAAGACCGCTCAAACGCGCAATTCAGCAGGAAATCGAAAATCC
GTTGGCACAACAAATTTTGTCCGGCAAATTATTACCGGCAAAACCTGTTACCGTGGATTACGAAGACGGCAAAGTGGTTG
CGAAACAGTAA

Protein sequence :
MNIEKFTTKFQQALAEAQSLALGKDNQYIEPVHVLSALINQQDGSVAPILTSAGVNVGALKAELNSEINKLPQVSGNGGD
VQISRQLLNLLNLCDKIAQRNNDKFISSELFLLAALEEKGSLGDLLKKCGAKKESLEQAIKTIRGGQSVNDQNAEESRQA
LEKYTIDLTERAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKGKRVLSL
DMGALIAGAKYRGEFEERLKAVLKELAQEEGKVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVDEPTVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPEPLDRLDRRIIQLKLEQQALKKEEDEASRKRLDMLEKELSEKEREYAELEEVWKSEKAALSGTQHIKAELE
SARTQMEQARRAGDLNKMSELQYGTIPALEKQLAAADSAEGKEMSLLRNRVTDEEIAQVLSRATGIPVSRMMEGEKEKLL
RMEEELHKRVIGQGEAVEAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFMFDDENAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQENKDLGYEGMKEIVMSVVGQHFRPEFINRIDETVVFHPLAKENIKAIAQIQLARLTKRMEQHGYAINFSETLLD
FISEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPAKPVTVDYEDGKVVAKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-155 46
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-104 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-101 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_088975.1 ClpA protein VFG0079 Protein 2e-151 45
clpA YP_088975.1 ClpA protein VFG2076 Protein 2e-107 43
clpA YP_088975.1 ClpA protein VFG2084 Protein 1e-104 41