Gene Information

Name : alr (MS1182)
Accession : YP_088374.1
Strain : Mannheimia succiniciproducens MBEL55E
Genome accession: NC_006300
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 1178644 - 1179717 bp
Length : 1074 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAAACCAGCAACAGTAAAAATCAGTTCAGTTGCACTGAAACATAATATTCAAATAATTAAACAGAAAGCACCGCACAG
TAAAATCATCGCTGTGGTGAAAGCAAATGCTTACGGACACGGCGTTGAATTTGTCTCTTCTACCTTAGAGAATTTAGTTG
ATGGTTTTGGTGTGGCGCGTTTAGCCGAAGCCCTTAGCGTCCGTTCTAACGGCGTAACCAAACCGATCCTTTTGTTGGAA
GGTTTTTTCTCTCCTAAAGATTTACCCATTCTTTCCGTCAATAATATTCAAACCGTCGTACATAACCAGGATCAATTGGA
TGCAATTAAACGGGCGAATCTTGAAAATCCGATAAAAGTCTGGCTGAAAATTGATACGGGCATGCACCGTTTAGGTGTTA
GTCTGGAAGAGGTGGATTATTACTATAACGAATTGATGAATTGTCCGAATGTGGATGAAGTGGGGTTTGTAAGCCATTTC
AGCCGCGCTGACGAAACCGACAGCGATTATACCAATATTCAGTTAAACCGCTTTTTGGATGCCACAAAAAACAAAAAAGG
CAACCGCACTATTGCGGCTTCCGGCGGCATTTTATTTTGGGAAGATTCCCATTTGGAATATATTCGTCCGGGGATCATTA
TGTATGGCGTATCGCCGATTAATATTCCGAGCAGTGAATACGGTTTGATCCCGGTGATGACCTTGACCTCTTCACTAATT
GCCGTGCGTGATCATAAAAAAGGCGAGCCTGTGGGTTACGGCGGTATTTGGGTGAGCGAGCGGGATACGAAAATCGGCGT
GGTGGCGATTGGCTACGGTGACGGTTATCCCCGCAATGTGCCGGCAGGTACACCGATTTATATTAATGGACGCCGGGTGC
CGATTGTCGGCCGTGTATCTATGGACATGGTTACGGTGGATCTCGGTCCCGATTGTAAAGACAAAGTAGGCGATGAAGCG
GTTCTTTGGGGGAAAGAATTGCCAATCGAGGAAGTGGCGGAAATTACCGGTCTGCTAAGTTATGAATTAATGACCAAATT
AACGCCGCGGGTTCTTACGGAATATGTTGATTAA

Protein sequence :
MKPATVKISSVALKHNIQIIKQKAPHSKIIAVVKANAYGHGVEFVSSTLENLVDGFGVARLAEALSVRSNGVTKPILLLE
GFFSPKDLPILSVNNIQTVVHNQDQLDAIKRANLENPIKVWLKIDTGMHRLGVSLEEVDYYYNELMNCPNVDEVGFVSHF
SRADETDSDYTNIQLNRFLDATKNKKGNRTIAASGGILFWEDSHLEYIRPGIIMYGVSPINIPSSEYGLIPVMTLTSSLI
AVRDHKKGEPVGYGGIWVSERDTKIGVVAIGYGDGYPRNVPAGTPIYINGRRVPIVGRVSMDMVTVDLGPDCKDKVGDEA
VLWGKELPIEEVAEITGLLSYELMTKLTPRVLTEYVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 9e-62 41