Gene Information

Name : clpC (BCZK0077)
Accession : YP_081693.1
Strain : Bacillus cereus E33L
Genome accession: NC_006274
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB (ATP-dependent Clp protease)
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 89681 - 92116 bp
Length : 2436 bp
Strand : +
Note : -

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCCCAAGAGGAAGCAATTCGTATTGGTCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGGGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTAG
GATTAAGTCCAGAGAAGGTTCAAAAAGAAGTAGAAGCGTTAATCGGACGCGGAACAGAAGTTTCTCAAACTGTACATTAT
ACACCGCGTGCCAAAAAGGTTATTGAGCTATCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTTTACTTGGTTTAATCCGCGAAGGTGAAGGGGTAGCGGCACGCGTTTTAAATAACTTAGGTGTTAGCCTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCACCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACAAAAAACAATCCTGTATTAATCGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCAGAAGGATTAGCACAACAAATTGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATTCGCCAAGCGGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAATATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAATGTATCGGGGCGACAACGTTAGATGAA
TATCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGCGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAACAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACATGGACTCGTATCCCGGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATCCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCAAAAGCTGTTCGCCGTGCTAGAGCAGGATTGAAAG
ATCCGAAACGTCCGATTGGCTCATTTATTTTCTTAGGACCAACAGGTGTAGGTAAAACGGAGTTAGCAAGAGCGTTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAACATTCTACTTCTCGTTT
AGTTGGATCTCCTCCAGGGTATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAAGTTCGCCGTAAGCCATATTCAG
TTGTCCTATTAGACGAGGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCGAAAGGGCGTACAGTTGATTTCCGCAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAGGCGTTAAA
ACGTAATAAGCATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAAGCCTTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCAATTAACAGAAGG
AGCAATTTCGGCCATTGCTGATAAAGGGTTTGACCGAGAGTACGGTGCTCGCCCACTTCGTAGAGCAATTCAGAAACATG
TAGAAGATAGACTATCGGAAGAACTGTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEVSQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELQLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_081693.1 negative regulator of genetic competence clpC/mecB (ATP-dependent Clp protease) VFG0079 Protein 0.0 77
clpC YP_081693.1 negative regulator of genetic competence clpC/mecB (ATP-dependent Clp protease) VFG0080 Protein 5e-148 52