Gene Information

Name : leuS (BCZK4490)
Accession : YP_086065.1
Strain : Bacillus cereus E33L
Genome accession: NC_006274
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4584985 - 4587393 bp
Length : 2409 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTTAATCATCAAGAAATTGAGAAGAAGTGGCAAGGGTACTGGGAAGAGAATAAAACATTCCGTACGCCAGATGA
GACAGAAAAACCAAAATTTTATGCACTAGATATGTTCCCATATCCATCAGGTGCAGGCCTACACGTAGGACATCCAGAAG
GTTATACAGCAACGGATATTTTATCTCGTATGAAGCGTATGCAAGGGTATAACGTTCTTCATCCAATGGGATGGGATGCA
TTCGGTCTTCCAGCAGAGCAATATGCACTTGATACTGGAAACAGCCCGGCTGAATTTACAGAGCATAATATTAATACGTT
CCGTAACCAAATTAAATCATTAGGTTTCTCTTACGATTGGGACCGTGAAGTAAATACAACAGATCCAAACTACTACAAGT
GGACACAATGGATCTTCCTAAAACTATTTGAAAAAGGCTTAGCTTATGTTGATGAAGTACCTGTAAACTGGTGCCCAGCA
CTTGGTACAGTACTTGCAAACGAAGAAATCATTGACGGTAAGAGTGAGCGCGGTGGACATCCAGTTGAGCGTCGTCCGAT
GAGACAGTGGATGTTAAAAATTACAGCTTACGGAGATCGTCTATTAGAAGATCTAGACGAGCTTGATTGGCCAGAAAGCT
TAAAAGATATGCAACGTAACTGGATTGGTCGTTCTGAAGGTGCAGAAGTACACTTCAACATCGACGGTACAGACGAGAAG
TTCACAGTTTTCACAACGCGCCCTGATACACTATTTGGTGCAAGCTACTGTGTACTTGCTCCGGAACATGCGCTTGTTGC
TGACATTACAACTGCTGATCAAAAAGAAGCTGTAGAAGCTTACATTAATTCTGTAAAAATGAAGAGTGATCTAGAGCGTA
CAGAACTTGCGAAAGAGAAAACTGGTGTATTCACTGGTGCTTACGCAGTTAACCCAGTAAATGGTGAGAAATTACCAATC
TGGATCGCTGATTACGTTCTTGCAACTTACGGAACAGGTGCTGTAATGGCGGTTCCAGCTCACGATGAGCGTGACTATGA
ATTTGCATCAACGTTCAATCTTCCAATGAAGGAAGTTGTAAAAGGTGGAGATATTACGAAAGAAGCATACACAGGTGATG
GTGCTCACGTAAACTCAGCATTCCTTGATGGTTTAAATAAAGAAGAAGCAATCGCAAAAATGATTGAATGGCTTGAAGTA
ACGAGCGCAGGAAATCAAAAAGTAACATACCGTCTACGTGACTGGTTATTCAGCCGTCAACGTTACTGGGGTGAGCCAAT
TCCAGTAATTCACTGGGAAGATGGCACAATGACAGCTGTGAAAGAAGAAGAATTACCATTAGTTCTTCCGAAAACAGAAA
ACATCCGTCCTTCAGGTACAGGTGAATCACCACTTGCTAATATTGACGAGTGGGTAAATGTTGTTGATCCTGAGACTGGT
AAAAAAGGTCGTCGTGAAACAAATACAATGCCGCAATGGGCTGGTAGCTGCTGGTATTACCTACGTTACATCGATCCAAA
CAATAGCGAAGCACTTGTAGATCCTGAAAAAGTAAAACAATGGCTTCCAGTTGATATTTATATCGGTGGTGCAGAACACG
CTGTACTTCACTTACTATATGCTCGTTTCTGGCATAAAGTATTATACGATATCGGTGTAGTTCCAACGAAAGAGCCGTTC
CAACAATTATTCAACCAAGGTATGATTCTAGGTGAAAACAACGAGAAAATGAGTAAATCAAAAGGTAACGTTGTAAACCC
TGATGATATCGTAGCAAGCCACGGTGCAGATACACTTCGTCTATACGAAATGTTCATGGGACCATTAGATGCTTCAATCG
CTTGGTCTGAAAATGGTCTTGACGGAGCTCGTCGTTTCCTAGACCGCGTATGGCGCCTATTCGTTCAAGATAACGGTGAA
TTAAGTGAGAAAATTACTGATGCACCAAATAAAGATCTTGAAAAAGCTTACCACCAAACAGTGAAGAAAGTAACAGAAGA
CTATGCAGAGCTTCGCTTTAACACAGCGATTTCTCAAATGATGGTATTCATCAACGATGCATACAAAGCTGAAACACTTC
CGAAAGAATATGTAGAAGGTTTCGTAAAAATGATTGCACCAGTTGCACCTCACATCGGGGAAGAGCTATGGAGCAAACTT
GGATACAATGAAACAATCACATATGCAAGCTGGCCAACATTCGATGAGTCTAAACTTGTAGAAGATGAAGTTGAAATCGT
TGTTCAAGTTATGGGTAAAGTTCGCGCAAAACTAACAATGAGTAAAGACGCATCAAAAGACGAAATGGAAAAACTTGCAC
TTGAAGCAATTCAAGACCAAATCGAAGGAAAAACAGTTCGTAAAGTAATTGTAGTTCCTGGAAAACTTGTTAACGTTGTT
GCAAACTAA

Protein sequence :
MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPA
LGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEK
FTVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPI
WIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEV
TSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETG
KKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPF
QQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGE
LSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKL
GYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKDEMEKLALEAIQDQIEGKTVRKVIVVPGKLVNVV
AN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67