Gene Information

Name : hemC (BCZK4208)
Accession : YP_085787.1
Strain : Bacillus cereus E33L
Genome accession: NC_006274
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4316228 - 4317157 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGCAAAATTATTGTAGGGTCACGAAAGAGTAAATTAGCATTAACGCAAACAAACTGGTTTATTGATCAGTTAAAAGC
GCTAGGTTTACCATATGAATTTGAAGTGAAAGAAATCGTCACAAAAGGTGATGTTATTTTAGATGTTACTCTTTCAAAAG
TAGGCGGAAAAGGTTTGTTTGTGAAAGAGATTGAACATGCGTTACTTACGAAAGAAATTGATATGGCTGTACATAGTATG
AAAGATATGCCGGCCGTACTTCCAGAAGGATTAATGATCGGTTGTACACCAAAGCGTGTTGACCCTCGTGATGCTTTTAT
CTCAAAAAGTGGGGCGTCGTTTAAAGAGTTAGCAGAAGGCGCTATTTTAGGTACGAGTAGTTTAAGACGTAGTGCACAGC
TGCTCGCTGCAAGACCAGATTTACAAGTGAAGTGGATTCGCGGAAATATCGATACACGTTTACGCAAATTAAAAGAAGAA
GATTACGATGCAATCATTTTAGCGACAGCTGGGTTACAAAGAATGGGCTGGGATGATGAAGTTATTACAGAACATTTAGA
TGAGACGTTATGTGTACCTGCTGTAGGACAAGGTGCATTAGCGATTGAGTGCCGTGAAGATGATACAGATTTACTACAGT
TGTTAGCGCATATAAATGATGCAGTAACAGAAAGAACAGTGGCAGCAGAACGAGTATTTCTTCATAAACTTGAAGGTGGG
TGCCAAGTTCCGATCGCTGGATATGCAACTCTTACAGAAAACGATGCAATCGAATTAACAGCTCTTGTCGGGTCTATGGA
CGGTTCTGTTTTGTTGAAAGAGACAGTAGTAGGAACTGATCCAGAGAAAGTAGGATTAGAGGCTGCGGACCGTTTAATTA
AACAAGGCGCAAAAGAACTCATTCTTGCTGCAAATAAGGGGCAACAATAA

Protein sequence :
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSM
KDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEE
DYDAIILATAGLQRMGWDDEVITEHLDETLCVPAVGQGALAIECREDDTDLLQLLAHINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKELILAANKGQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-57 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-57 48