Gene Information

Name : metC (BCZK4116)
Accession : YP_085695.1
Strain : Bacillus cereus E33L
Genome accession: NC_006274
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4222791 - 4223924 bp
Length : 1134 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGAGCAAAGACAAAGTTAATTCATGGTATTCGCATAGGAGAACCTTCAACTGGATCTGTAAATGTACCGATTTATCA
AACGAGTACGTACAAACAAGAAGCAGTTGGTAAGCATCAAGGATATGAATATTCACGTACAGGAAACCCAACACGTGCAG
CTTTAGAAGAAATGATTGCTGTATTAGAAAACGGTCATGCTGGTTTTGCATTTGGCTCAGGAATGGCGGCTATTACAGCT
ACGATTATGTTGTTCTCAAAAGGTGACCACGTTATTTTAACAGATGATGTGTATGGTGGAACGTACCGCGTGATTACGAA
AGTATTAAACCGCTTCGGTATTGAGCATACATTTGTAGATACAACAAACTTAGAAGAAGTTGAAGAAGCGATTCGTCCAA
ATACGAAAGCGATTTATGTAGAAACACCAACGAATCCACTACTAAAAATTACTGATATTAAAAAAATATCTACTCTTGCT
AAAGAGAAAGATTTATTAACAATTATTGATAACACATTCATGACGCCATATTGGCAGTCGCCGATTTCTTTAGGGGCAGA
TATTGTACTTCATAGTGCAACAAAATATTTAGGAGGTCATAGTGACGTAGTTGCAGGTTTAGTAGTTGTAAATAGCCCGC
AATTAGCAGAAGACCTTCACTTTGTACAAAACTCAACAGGAGGCATTCTTGGCCCGCAAGATAGCTTCTTACTACTTCGT
GGTTTAAAAACATTAGGAATTCGAATGGAAGAGCATGAAACGAATTCACGCGCAATTGCTGAGTTTTTAAATAATCATCC
AAAAGTAAATAAAGTATATTACCCAGGTCTTGCATCACATCAAAACCATGAATTAGCAGCAGAACAAGCAAATGGATTTG
GTGCGATTATCTCATTTGATGTAGATAGCGAAGAAACATTAAATAAAGTACTTGAGAGATTACAATACTTTACACTGGCT
GAAAGTTTAGGAGCAGTAGAAAGTTTAATTTCTATCCCATCTCAAATGACACATGCATCAATCCCAGCAGATCGTCGCAA
AGAACTAGGAATTACAGATACATTAATTCGAATTTCTGTCGGTATTGAAGACGGAGAAGATTTAATTGAAGATTTAGCAC
AAGCGTTAGCATAG

Protein sequence :
MRAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKHQGYEYSRTGNPTRAALEEMIAVLENGHAGFAFGSGMAAITA
TIMLFSKGDHVILTDDVYGGTYRVITKVLNRFGIEHTFVDTTNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTLA
KEKDLLTIIDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGGILGPQDSFLLLR
GLKTLGIRMEEHETNSRAIAEFLNNHPKVNKVYYPGLASHQNHELAAEQANGFGAIISFDVDSEETLNKVLERLQYFTLA
ESLGAVESLISIPSQMTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-114 61
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-113 60
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-82 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_085695.1 cystathionine beta-lyase BAC0207 Protein 5e-65 41