Gene Information

Name : metC (BCZK4008)
Accession : YP_085588.1
Strain : Bacillus cereus E33L
Genome accession: NC_006274
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4117780 - 4118943 bp
Length : 1164 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGTTATTCTATAGATACACTCTTACTACACAACCAATATAAACATGATCCACAAACAGGAGCGGTTAACGTTCCCAT
CTATAACACATCAACATTCCACCAGTTCGATGTAGATACGTTCGGGAAATATGACTATAGCAGGTCAGGAAATCCAACTC
GTGAAGCTCTTGAAGACATCATTGCTTTATTAGAAGGCGGAACAAAAGGATTTGCCTTCGCATCAGGAATTGCAGCGATT
TCTACTGCATTCCTCCTTCTTTCACAAGGTGATCACGTACTCATTTCAGAAGACGTATACGGAGGGACTTATCGAATAAT
AACTGAAGTTCTCTCCCGTTACGGTGTTTCACATACATTTGTTGATATGACCAATCTAGAAGAAATCAAGCAAAATATAA
AACAAAATACAAAGCTCTTTTATGTAGAAACACCTTCTAACCCGCTTTTAAAAGTAACAGATATTCGTGCTGTTTCTACA
CTTGCAAAATCTATTGGCGCTCTTACTTTTGTTGATAATACATTTTTGACACCACTATTCCAGAAACCACTTGATCTCGG
CGCAGATGTCGTTCTTCATAGCGCTACAAAGTTCATTGCTGGTCACAGTGATGTTACTGCTGGATTAGCGGTCGTAAAAG
ATGCCGAACTTGCTCAAAAACTTGGATTTTTACAAAATGCATTCGGCGCCATTTTAGGACCTCAAGATTGCTCTCTCGTA
CTTCGCGGTCTAAAAACATTGCATGTACGTCTTGAGCATTCAGCTGCGAATGCCAATAAAATTGCACAGTATTTACAAGA
GCACAGTAAAATTCAAAATGTCTATTATCCTGGCTTACAAACACATCTTGGATTTGATATTCAACAATCTCAAGCAACAT
CGGCCGGAGCTGTCCTATCCTTCACTTTACAATCAGAAGATGCACTCCGCCAATTTTTATCAAAAGTAAAATTACCTGTC
TTTGCAGTTAGTTTAGGAGCTGTTGAATCGATTCTTTCCTACCCAGCTAAAATGTCACATGCAGCACTGTCACAAGAAGC
TCGTGATGAAAGAGGTATTTCCAACTCATTACTTCGTTTATCCGTCGGCCTTGAAAATGTTGATGATTTAATATCTGACT
TTGAAAATGCCCTTTCTTATGTAGAAGAACCAGTAAATGCATAG

Protein sequence :
MSYSIDTLLLHNQYKHDPQTGAVNVPIYNTSTFHQFDVDTFGKYDYSRSGNPTREALEDIIALLEGGTKGFAFASGIAAI
STAFLLLSQGDHVLISEDVYGGTYRIITEVLSRYGVSHTFVDMTNLEEIKQNIKQNTKLFYVETPSNPLLKVTDIRAVST
LAKSIGALTFVDNTFLTPLFQKPLDLGADVVLHSATKFIAGHSDVTAGLAVVKDAELAQKLGFLQNAFGAILGPQDCSLV
LRGLKTLHVRLEHSAANANKIAQYLQEHSKIQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEDALRQFLSKVKLPV
FAVSLGAVESILSYPAKMSHAALSQEARDERGISNSLLRLSVGLENVDDLISDFENALSYVEEPVNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-88 52
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-86 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-87 47