Gene Information

Name : dhbE (BL04022)
Accession : YP_080978.1
Strain : Bacillus licheniformis DSM 13
Genome accession: NC_006270
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3726411 - 3728033 bp
Length : 1623 bp
Strand : -
Note : -

DNA sequence : 
ATGCTGAAAGGATGCACGACATGGCCGAAGGAGTTTGCGGATAAATATCGGAAGGAGGGATGCTGGCGAGGCGAAACTTT
TGGAAAAATGCTGAGGGAGCGGGCCGAAAAATACGGAAGCCGCATTGCCCTTACATACGGAGATATCCATTTAAGCTATC
GTGAGTTAGACAGGAGAGCCGATTCTTTGGCTGGCGGTCTTTTAAAGCTGGGGATCAAAAAAAATGATCGCGTCGTTGTC
CAGCTGCCGAATATCATCGAGTTTTTTGAAGTTTGCTTTGCGCTCTTCCGGATCGGAGCTCTGCCTGTTTTTGCGCTTCC
ATCGCATCGGCATAGCGAGATCACGTATTTTTGCGAGTTTTCTGAAGCTGCTGCCTACATTATTCCCGATCGTCACGCAA
AGTTTGACTACCGCAAGCTGGCGAGACAGGTAAAGGAGAAGCTGCAAGGGCTCCGTCATGTCATTGTCGCCGGGGAACCG
GAGGAGTTTGAAGCGCTGGCAAGCCTTTATGATCAGCCGGCACCTCCGCAAAACGTCTATCCAGAAGATGTCGCCTTTCT
TCAGTTGTCGGGGGGAAGCACAGGTCTGTCCAAGCTGATCCCGAGGACGCATGATGATTATATATACAGCTTGAGGGTCA
GCGCAGAGATTTGCAGGCTCGATCACAACAGCGTATATCTTGCGGCTCTTCCGATCGCTCACAATTATCCGCTCAGCTCG
CCGGGAGTGCTCGGTACGCTGTACGCGGGAGGCCGAGTCGTCCTTGCATCAGGAGGCAGCCCGGATGAAACCTTCCCTCT
GATCGATAAGGAGAGGGTAACGATCACGGGACTCGTACCGCCGCTTGCGTTAATCTGGCTTGATGCTGCTTCGGCGCGCC
GGGACGACTTGTCAAGCCTCCAGGTCTTTCAAGTCGGCGGAGCGAAATTCAGCGCCGAAGCTGCCAGACGCGTTTCATCG
GTGTTTGGCTGCAAACTGCAGCAGGTTTATGGCATGGCAGAAGGTCTGGTCAACTATACCAGACTTGATGATCCTGAAGA
CACGATCGTTCACACACAAGGCAGGCCAATGTCTCCGTTTGACGAGATTAAAATTGTGGACGAAAAAGGACGCGAACTTG
GACCCGGACAGACAGGAGAGCTGCTGACAAGAGGTCCATATACGATTCGCGGCTATTACAAAGCTGAGGAGCACAATGCC
AAAGCGTTCACTGAAGACGGGTTTTACCGTACGGGAGACTTGGTTAAAGTCAATTCATCAGGCTATTTGATTGTTGAAGG
ACGAGCTAAAGACCAGATCAACAGAGGCGGTGAGAAGGTTGCCGCGGAAGAAGTGGAAAACCATCTGCTCGCACATCCGG
GGGTACTCGATGCGGCGGTTGTCTCGATGCCGGATCAATTTCTCGGCGAAAGGGCGTGTGCATATATTATCCCTCGCGGC
GCTGCACCGGCTCAGGCTGAGTTGCAATCGTTTTTGAGAGAAAGGGGCCTTGCAGCCTACAAAATACCCGACCGGGTAGA
AATGGTTGAAGATTTCCCGCAGACAGGCGTAGGAAAAGTCAGCAAAAAAGAGCTGCGTGCGGCGATTGCTGAAAAAATGT
CTGCAGCTGAGAATGTCAGATGA

Protein sequence : 
MLKGCTTWPKEFADKYRKEGCWRGETFGKMLRERAEKYGSRIALTYGDIHLSYRELDRRADSLAGGLLKLGIKKNDRVVV
QLPNIIEFFEVCFALFRIGALPVFALPSHRHSEITYFCEFSEAAAYIIPDRHAKFDYRKLARQVKEKLQGLRHVIVAGEP
EEFEALASLYDQPAPPQNVYPEDVAFLQLSGGSTGLSKLIPRTHDDYIYSLRVSAEICRLDHNSVYLAALPIAHNYPLSS
PGVLGTLYAGGRVVLASGGSPDETFPLIDKERVTITGLVPPLALIWLDAASARRDDLSSLQVFQVGGAKFSAEAARRVSS
VFGCKLQQVYGMAEGLVNYTRLDDPEDTIVHTQGRPMSPFDEIKIVDEKGRELGPGQTGELLTRGPYTIRGYYKAEEHNA
KAFTEDGFYRTGDLVKVNSSGYLIVEGRAKDQINRGGEKVAAEEVENHLLAHPGVLDAAVVSMPDQFLGERACAYIIPRG
AAPAQAELQSFLRERGLAAYKIPDRVEMVEDFPQTGVGKVSKKELRAAIAEKMSAAENVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 8e-117 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-117 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-117 50
ybtE CAA21394.1 - Virulence HPI Protein 8e-117 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-116 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-117 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-116 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-116 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-117 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_080978.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-142 55
dhbE YP_080978.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-113 48
dhbE YP_080978.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-110 45