Gene Information

Name : tpx (BL00421)
Accession : YP_080231.1
Strain : Bacillus licheniformis DSM 13
Genome accession: NC_006270
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2975124 - 2975627 bp
Length : 504 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTTCAATTACATTTAAGGGAAACCCGGTGACACTGGTGGGTTCAGAAGTGAAAGTCGGAGACCAGGCGCCTGATTT
CACGGTTTTGTCCAATTCGCTTGAGGAAGTCACACTTCAGGACATCAAAGGCAAACCGGCGGTTATTTCGGTGATTCCGT
CTATCGATACAGGTGTTTGTGACGCACAGACCCGCCGCTTTAACGAAGAAGCCGCAGGCCTCGGTTCGGTGAAAGTGTAT
ACGATCAGCGCTGACCTGCCGTTTGCACAGGCGCGCTGGTGCGGAGCAAACGGAATTGAAAATGTGGAAACATTGTCAGA
TCACAGGGAGATGTCTTTTGGGGAAGCATTCGGGGTTTACATTAAAGAATTGAGATTGCTTGCCCGCGCCGTATTTGTTT
TAGATGAAAACGGAAAAGTTGTCTACACTGAATACGTCAGCGAAGCGACAAACCATCCGGACTACGACAAAGCCATCGAA
GCTGCCAAATCACTCGTTAAGTAA

Protein sequence : 
MASITFKGNPVTLVGSEVKVGDQAPDFTVLSNSLEEVTLQDIKGKPAVISVIPSIDTGVCDAQTRRFNEEAAGLGSVKVY
TISADLPFAQARWCGANGIENVETLSDHREMSFGEAFGVYIKELRLLARAVFVLDENGKVVYTEYVSEATNHPDYDKAIE
AAKSLVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-22 43
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 1e-22 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-23 43
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 7e-23 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_080231.1 thiol peroxidase VFG0087 Protein 3e-23 43