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Name : leuS (STH444) Accession : YP_074273.1 Strain : Symbiobacterium thermophilum IAM 14863 Genome accession: NC_006177 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 480794 - 483379 bp Length : 2586 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGCAGAGGAACGCTTCGACTTCCGGGAAGCCGAGCCCCGGTGGCAGCGCCGGTGGGACGAGGAGGGCATCTACAAGGT CGAGAGAGACCTGAGCCGGCCGAAGTATTACGCGCTGGCGATGTTCCCCTACCCGTCGGGCAAGCTGCACATGGGCCACG TGCGCAACTACACCATCGTCGACGTCATCGCCCGCTACCGGCGGATGAAGGGGTACAACGTGCTGCATCCCATGGGGTTC GACTCCTTCGGCATGCCGGCGGAGAACGCGGCCATCCAGCACGGCGCCAACCCGGCGGTATGGACGCGGGAGAACATCGC CGAGATGACGGCGCAGCTGAAGCAGATGGGGTACTCCTACGACTGGTCCCGGGCGGTGTACACCTACCGCGAGGACTATT ACCGGTGGACCCAGTGGCTCTTCCTGCAGTTCTACAAGAAGGGGCTGGCGTACAAGAAGACCGCCCCGGTCAACTGGTGT CCCTCCTGCCAGACCGTGCTGGCCAACGAGCAGGTGGAGGACGGCCGGTGCTGGCGCTGCGACTCGGTGGTCACCAAGAA GGACCTCGCCCAGTGGTTCTTCCGCATCACCCAGTACGCCGATGAGCTGCTGGAGGATCTGAAGCTGCTGGAGGGCGGCT GGCCCGAGCAGGTCCGCATCATGCAGCAGAACTGGATCGGCCGCTCCGAGGGCGCCAGGGTGGAGTTCACGCTGGAAGCC ACGGGCGACAAGATCCCGATCTTCACCACCCGGCCGGACACCATCTACGGCGTCACCTTCATGGTGGTCGCCCCGGAGCA TCCGATCGTGGAGAAGATCTGCACCTCCGGCCTGATCCCGGAGGAGCGGGTGGCCGCCATCCGGGCCTTCCAGGAGAAGA TGAAGCACCTCTCCGAGATCGCCCGTACCTCCACCGAGGCGGAGAAGGAAGGGCTGTACACCGGGCTTGACGTCATCAAC CCGTTCAACGGGGAGAAGGCGCAGCTCTGGATCGCCAACTACGTGCTGATGGACTACGGCACCGGCGCCGTGATGGGCGT GCCCGCCCACGACCAGCGGGACTTCGAGTTCGCGCAGAAGTACGGGCTGCCGGTGAAGGTGGTCATCCAGAACCCGGAGG GGACGCTCAGGGCGGAGGAGATGACCGCGGCCTACGTCGAGCCGGGGATCATGGTCAACTCCGGCCCCTTTGACGGGACG CCCAACCTGGAGGGCATCCCCAAGGTTATCGCCTACGCCGAGGAGCAGGGGTTCGGCCAGAAGACCGTCTCCTACCGGCT GCGGGACTGGCTGATCAGCCGTCAGCGGGCCTGGGGCGCGCCGATCCCCATCGTGTACTGCGACAAGTGCGGCACCGTCC CCGTGCCGGAGAAGGACCTGCCCGTGCGGCTGCCGGACGACCTGGATTTCACCGGCGAGGGCGGCTCGCCGCTGGCCCGG CACGAGGGCTTCGTGAACACCACCTGCCCGCAGTGCGGCGGCCCCGCCCGGCGGGAGACCGACACGATGGACACCTTCGT CTGCTCCTCCTGGTACTTCCTGCGTTACACCGACCCGCAGAACGCGGAGAGGCCGTGGAACCGGGAGGACGTGGACTACT GGATGCCGGTGGACCAGTACGTGGGCGGCATCGAGCATGCCGTGCTGCACCTGCTCTACGCCCGCTTCTTCACCAAGGTC CTGCGGGACATGGGGCTGGTGAAGGTCGACGAGCCCTTCGCCCGGCTGCTCACCCAGGGTATGGTGCTGAAGGACGGCTC CAAGATGTCCAAGTCCAAGGGCAACACCGTCTCCCCTGAGGAGATGATCGCCAAGTACGGCGCCGATGCCGTGCGGCTGT TCATCATGTTCGCCGCCCCGCCGGAGCGCGACCTGGACTGGTCGGACGCCGGCATCGAAGGGGCCGCACGGTTTGTCAAC CGCTTCTACCGCATGGTCGTTTCGGCGCTGCCCGCCTACCAGCACGCCCGCAGCCTGCTGCCCATCAACCCGGCCGACCC GGCGTCGGTCATGGGCGCCCTCTCCGAGGCGGAGATCGCCGAGGGGCTGGCCAAGGCCGCCCCGAACCTGACGGCGGAGG ACCGGGAGCTCCGGCGGGTCATCCATGCCACGGTCAAGCGCATCACGGCCGACCTGCACGACCGGTTCGCCTTCAACACG GCGATCTCCGGCCTGATGGAGATGACCAACGCCATCTACGCCTACCGGGAGAAGCAGCACGCGGAGCAGAACACCAGCGC GCTGGTGCTGGCCGAGGCGGTGCAGAAGGCGGTGCTCATCATCGCTCCGTTCTGCCCGCACCTGGCCGACGAGCTGTGGT CCCGGATGGGTCACCCCCGCTCCATCCACCTGGAGCCCTGGCCGGCGTACGACGAGGAGGTCGCCAAGGCCGACACCGTC GAGATCGTCGTGCAGATCAACGGCCGGGTGCGCGACCGGCTGGAGGTGCCGGCGGGCATCAGCGCCGCCGAGATGGAGGC GGTGGCCATGGCTTCCGAGAAGGTGCAGGCGCTGGTGGCCGGGAAGCAGATCGTGAAGGTCGTTCCGGTGCCGGGCAAGC TGGTCAACATTGTGGTGAAAGGGTAA Protein sequence : MAEERFDFREAEPRWQRRWDEEGIYKVERDLSRPKYYALAMFPYPSGKLHMGHVRNYTIVDVIARYRRMKGYNVLHPMGF DSFGMPAENAAIQHGANPAVWTRENIAEMTAQLKQMGYSYDWSRAVYTYREDYYRWTQWLFLQFYKKGLAYKKTAPVNWC PSCQTVLANEQVEDGRCWRCDSVVTKKDLAQWFFRITQYADELLEDLKLLEGGWPEQVRIMQQNWIGRSEGARVEFTLEA TGDKIPIFTTRPDTIYGVTFMVVAPEHPIVEKICTSGLIPEERVAAIRAFQEKMKHLSEIARTSTEAEKEGLYTGLDVIN PFNGEKAQLWIANYVLMDYGTGAVMGVPAHDQRDFEFAQKYGLPVKVVIQNPEGTLRAEEMTAAYVEPGIMVNSGPFDGT PNLEGIPKVIAYAEEQGFGQKTVSYRLRDWLISRQRAWGAPIPIVYCDKCGTVPVPEKDLPVRLPDDLDFTGEGGSPLAR HEGFVNTTCPQCGGPARRETDTMDTFVCSSWYFLRYTDPQNAERPWNREDVDYWMPVDQYVGGIEHAVLHLLYARFFTKV LRDMGLVKVDEPFARLLTQGMVLKDGSKMSKSKGNTVSPEEMIAKYGADAVRLFIMFAAPPERDLDWSDAGIEGAARFVN RFYRMVVSALPAYQHARSLLPINPADPASVMGALSEAEIAEGLAKAAPNLTAEDRELRRVIHATVKRITADLHDRFAFNT AISGLMEMTNAIYAYREKQHAEQNTSALVLAEAVQKAVLIIAPFCPHLADELWSRMGHPRSIHLEPWPAYDEEVAKADTV EIVVQINGRVRDRLEVPAGISAAEMEAVAMASEKVQALVAGKQIVKVVPVPGKLVNIVVKG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-153 | 42 |
