Gene Information

Name : serS (STH10)
Accession : YP_073839.1
Strain : Symbiobacterium thermophilum IAM 14863
Genome accession: NC_006177
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 12383 - 13648 bp
Length : 1266 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATTTGAGGTTCGTTCGCACCAATCCCGACGTCGTTCGTCAGGCGCTGATCAACAAGGGTGTTTCCGTCGACCT
GGACCGCATCCTGGCCCTGGACGTGGAGAGGCGGCAGATTCTGGCCGAGGTCGAGCAGTTGAAAGCGCGCCGCAACCAAG
TGTCCAAGCAGGTGGGCATCCTGAAGCAGCAGGGGCAGGACGTCAGCGCGATCATCGCGGAGATGGGCGCCATCGGCGAC
CGCATCAAGGAGCTGGATGACCGGGAGCGGCAGGTGTCCGATGAGCTGCAGGACCTGCTTTACCAGCTGCCCAACCTCCC
CGCGCCCGACGTGCCGGTCGGCCCGGACGAAACCGGCAACGTCGAGGTGAAGCGGTGGGGCGAGCCCCGCCAGTTCGCCT
TCCCGGTGAAGCCTCACTGGGACCTGGGGGTGGCCATGGACGGCCTGGACTTCGAGCGGGCCGCCAAGGTCACCGGCAGC
CGTTTCTCGTTCATCAAGGGCGGGCTGGCCCGGCTGCACCGCGCCCTGGTCAGCTTCTTCATCGACTACCTCACCGAGCG
GGGCTACCGCGAGGTGCTGCCGCCCGTGATCATCAACACCGCCAGCTACTACGGCAGCGGCCAGTTCCCGAAGTTCAAGG
AGGACGTCTTCAGCCTGGCCGGGACCGACTACCACCTTGCCTCCACCGCCGAAGTGCCGCTGGTCAACATGCACCGGGAC
GAGATCCTGGACGAGGCCGTTCTGCCCCTGAGGTACGTGGGCTACAGCGGGTGTTTCCGCAGTGAGGCCGGCGCGGCCGG
CCGCGACACCCGCGGCCTCATCCGGCAGCACTACTTCGAGAAGGTCGAGATGGTGCAGTTCACCCGGCCCGAGGAGAGCG
AACAGGCCCTCATGGAGATCGTGGCCAACGCCGAGGGCATGCTGGAGCAACTCAACCTGCCGTACCGGCGCATGCTCATG
TGCACGGGCGACATGGGCTTCGGGCAGTACAAGAAGTACGACATCGAGGTGTGGATGCCCAGCTACGAGCGGTACGTGGA
GATCTCGTCCTGCTCCAACATGAGCGACTTCCAGGCCCGCCGCGCGAACATCCGCTACCGTCCTGCCGGAGGCAAGCCGG
AGTTCGTGCACACGCTGAACGGCTCGGGCCTGGCCGTGGGCCGCACGCTCGCCGCGGTGATGGAGAACTACCAGAACGAG
GACGGTTCCATCACGGTGCCGGAGGTGCTGCGGCCGTACACCCGGTGTGAGCGCATCGAACGATAA

Protein sequence :
MLDLRFVRTNPDVVRQALINKGVSVDLDRILALDVERRQILAEVEQLKARRNQVSKQVGILKQQGQDVSAIIAEMGAIGD
RIKELDDRERQVSDELQDLLYQLPNLPAPDVPVGPDETGNVEVKRWGEPRQFAFPVKPHWDLGVAMDGLDFERAAKVTGS
RFSFIKGGLARLHRALVSFFIDYLTERGYREVLPPVIINTASYYGSGQFPKFKEDVFSLAGTDYHLASTAEVPLVNMHRD
EILDEAVLPLRYVGYSGCFRSEAGAAGRDTRGLIRQHYFEKVEMVQFTRPEESEQALMEIVANAEGMLEQLNLPYRRMLM
CTGDMGFGQYKKYDIEVWMPSYERYVEISSCSNMSDFQARRANIRYRPAGGKPEFVHTLNGSGLAVGRTLAAVMENYQNE
DGSITVPEVLRPYTRCERIER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-103 54