Gene Information

Name : leuS (BG0254)
Accession : YP_072699.1
Strain : Borrelia garinii PBi
Genome accession: NC_006156
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 255253 - 257775 bp
Length : 2523 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCTAAATACGAATTCATAAAAATTGAAAAAAAATGGCAAGAATTTTGGGATAATAATAAAACATACAAAGTAAAAGA
AGATCCAAACATTCCTAAAGAAAAAAGATTATACATCCTTGACATGTTCCCCTATCCTTCTGCAAACGGACTTCATGTTG
GCCATCCAGAAGGATACACAGCTACCGACATATTTGGAAGATACAAGCTTTTAAATGGATTTCATGTACTTCATCCAATA
GGATTTGATAGTTTTGGACTGCCTGCTGAAAATTATGCAATACAAACAGGAACTCATCCTCAAAAAAGTACAGAAGAAAA
TATTAATAAGTTTAAAAAACAAATAAAAGCTTTGGGATTTGCCTACGATTGGGATCGAGAAATCAGAACACATGACGAGA
ATTACTATAAATGGACACAATGGATTTTTTTGGAATTATATAAAAAAGGTCTGGCCTATGCAAAAGAAATGCCTGTATGG
TACTGTCCTGAACTTGGAACAGTATTGGCAAATGAAGAGATTATTCAAACTCCAGATGGACCAAAATCTGAGAGAGGATT
TCACAATGTCGAAAAAAAATATTTAAGACAGTGGGTTTTAAAAATCACGAAGTATGCTGAAAGATTGTTAAACGACCTTG
AAGAATTAGAATGGCCTGAATCTGTAAAAGAAATGCAGCGAAATTGGATTGGAAAATCAACAGGGGTTGAAATCGACTTT
GAAATTGAAGGTCACAATGATAAAATCAAAGTTTTTACAACAAGGCCAGACACAATCTTTGGTATCACATATTTAGTAAT
CGCACCAGAAAGCAAGCTAATAGAGAAAATAACAAAAAATAACTTTAAAAGAAATGTCTTAAAATATGTAAAGCACGAAG
AACTAAAAAGTGATCTTAAGAGAACCTCTCTTGAAAAAGATAAATCAGGCGTTTTTACAGGATCTTATGCATTTCATCCA
ATAACAAATGAAAAAATTCCAATTTGGATTGGAAGCTACGTACTAGGAACTTATGGTAGTGGAGCTGTAATGGGTGTTCC
AGCCCACGATGAGAGAGACTTTCAATTTGCTAAAAAGTATAAATTAAAAATTTTGCCTGTAATATCAAAATCGGGAAAAA
ATGAAATATTAGAAAAAGCATTTATTGATGATGGAATTTCAATAAATTCTCCTAATGAATTTAATAATCTTAAAAATTCT
GAAGTAAAAGATAAAGTAATAGAATGGCTTATTAAAAACAAAAAAGGGAAAGAAAAAGTTACCTACAAGCTTAGAGATTG
GATTTTTTCAAGACAAAGATACTGGGGAGAGCCTATACCCATTTTATTTGATAAGCTTGGAAATGCAGTACCTTTAGAAA
AAAATGATCTTCCCTTAAAGCTTCCAAAAACTGCAAACTATAAACCTTCTAGAACGGGAGAATCTCCTTTATCAAGGATT
AAAGATTGGGTAAACCTAAAAGATACAGGCTTTACAAGAGAAACAAACACAATGCCTCAATGGGCAGGCTCTTGTTGGTA
TTATTTAAGATACCTCGATCCTAAAAACCCAAAAGAATTTGCAAGTAAAAAAAAAATTGAATATTGGATGCCAGTTGACC
TATACATAGGTGGAGCTGAACATACGGTATTACACCTACTTTACTCAAGGTTTTGGCACAAGGTTCTTTATGATCTAGGG
TATGTAAATACCAAAGAACCTTTTAAAAAGCTAATAAATCAAGGCATAATAACCGCATTTTCTTATCAAAAAGAAAATGG
GATTTTAATACCTAATGACCAAGTTATAGAAAAAAACAGTAAATTTTTTGACAAAAGGGATAATAAAGAAGTAATCCAAG
TAATTGCCAAGATGTCAAAATCCTTAAAAAATGTAATAAACCCAGACGACATTATTAAAGAATTTGGAGCAGACTCAATA
AGAATTTATGAAATGTTTATGGGTCCACTAACAGATTCTAAACCTTGGAACACCAAAGGTATTATTGGTGTTTTTCGATT
TTTAAACAAAATTTGGAACTTAAGAGAAAAAGAACTATCAAAAGACAATCCTCCAAAAGAAATAATATCTCAACTGCATA
AAGCAATAAAAAAGGTCACAGAAGATACAGAAAAACTAAGCTTCAATACAGCAATCTCAGCGATGATGATATTTGTAAAT
GAGCTTATAAAGTATGAAAAAAATTATTTAAATATATTTAAACCATTCATTATTATTTTATCCCCTTATGCACCCCATTT
AGCAGAAGAGTTATGGGAATATATTGGAGAAACTCCCAGTTTATTTAAAAATTCAAAATGGCCAGAATTCGATGAAAACC
TTATTATTAAAGACGCAAAAGAAATTGTCTTACAAATAAATGGAAAAATGAAAGACAAAATTTTACTAAGCAAAGAGACA
GATGAAGAAGAGTTAAAAGAAATAGCAATGGGAAATAGCAAAATAAAAGCAAACTTATTAAATAAAAAAATTGTAAAAAT
AATTGCAATTAAAAACAAGCTTGTCAACATAGTGATAAAGTAA

Protein sequence :
MSKYEFIKIEKKWQEFWDNNKTYKVKEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYTATDIFGRYKLLNGFHVLHPI
GFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGFAYDWDREIRTHDENYYKWTQWIFLELYKKGLAYAKEMPVW
YCPELGTVLANEEIIQTPDGPKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF
EIEGHNDKIKVFTTRPDTIFGITYLVIAPESKLIEKITKNNFKRNVLKYVKHEELKSDLKRTSLEKDKSGVFTGSYAFHP
ITNEKIPIWIGSYVLGTYGSGAVMGVPAHDERDFQFAKKYKLKILPVISKSGKNEILEKAFIDDGISINSPNEFNNLKNS
EVKDKVIEWLIKNKKGKEKVTYKLRDWIFSRQRYWGEPIPILFDKLGNAVPLEKNDLPLKLPKTANYKPSRTGESPLSRI
KDWVNLKDTGFTRETNTMPQWAGSCWYYLRYLDPKNPKEFASKKKIEYWMPVDLYIGGAEHTVLHLLYSRFWHKVLYDLG
YVNTKEPFKKLINQGIITAFSYQKENGILIPNDQVIEKNSKFFDKRDNKEVIQVIAKMSKSLKNVINPDDIIKEFGADSI
RIYEMFMGPLTDSKPWNTKGIIGVFRFLNKIWNLREKELSKDNPPKEIISQLHKAIKKVTEDTEKLSFNTAISAMMIFVN
ELIKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPEFDENLIIKDAKEIVLQINGKMKDKILLSKET
DEEELKEIAMGNSKIKANLLNKKIVKIIAIKNKLVNIVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 52