Gene Information

Name : hofB (YPTB0706)
Accession : YP_069247.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : N : Cell motility
COG ID : COG2804
EC number : -
Position : 845082 - 846620 bp
Length : 1539 bp
Strand : -
Note : similar to Yersinia pestis YPO3426 hofB, hopB; type II secretion system protein (99.8% evalue=0); Escherichia coli Z0117 hofB; integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake (45.3% evalue=1.E-112)

DNA sequence :
ATGGCTGAATTTACAGTGTCCTCATTTGAAACAATTAGTGATGAATTACACCTTCTCTGTCGGCGTTATCGGGCAGTGGC
ACTCACTCTTGATGGTAAAAGCCTTTCGATAGCTTCAGCCCAGACCGTTGATGAAGCGTTATTGACCGCGTTGCGTTTCA
CATGTGGCCGTCAAGTCAGAGTGGAATATTGGCCCGAAGCCAAGATTGAACAATCATTGTATTTGGGGAGCCCGACGAAA
AATAACCTAAACAGTAGTATTAACAACGGGCTAAATAGCGCGTTGTTATCCCAAAAGGGAGGTGATCCGTCGCGAGTAAA
ACCGCACAATCAGCAGCAACAGACAATAGATGATACTGTGTTTGATAATGAGAGTGACACACCCGTCATTCAATTCATAA
CCCAGACGCTAAGTCTAGCCATTCAAAAACGCGCTTCAGATATCCATTTTGAGCCTTATCAACACCACTATCGTGTTCGT
TTAAGAATTGATGGTGTGTTGCATGAATTCACCCCACCCGAGGCCGAATGGGCAGCTCGGATTAGCAGTTGCCTGAAGGT
CATGGCGAAATTAAATATTGCTGAACGGCGATTACCACAAGATGGTCAACTAACCTTACCCTTTGGTGATTCACACTATT
CAATGCGGATAGCGACTCTCCCTACGCAATATGGTGAAAAAGTGGTATTGCGTATTCTTCAAATACAACAGCAAACCACG
TTAGAAAAGCTGGGGATGACGGATGCGGCACTGAAACAATTAACACAGGCATTATCAGCACCACAAGGGCTGATTCTGGT
CACCGGCCCTACCGGTAGTGGCAAAACCATTACGTTATATTGCAGTTTAGCGCGGCTGAATCAGACACAAAGAAACATCT
GTAGCGTCGAAGATCCTATTGAGATCCCCGTCAATGGCATTAACCAAACCCAGGTAAACAGCAAGATCGGTCTGGATTTC
TCTCGAATACTACGAGCCATCCTACGTCAGGACCCTGATGTCATTATGGTTGGTGAAATTCGTGATAATGAAACCGCCAG
TATCGCAGTTAACGCGGCCCAGACCGGGCATTTGGTCCTATCGACGCTGCACACTAACTCAACAGCAGAAACGCTGATAC
GCATGGCACAAATGGGAATAGAACGCCATTTAATCGCCTCAAGTCTAAAACTCGTCATTGCTCAACGCTTGGTGCGCCGC
CTATGTTTACATTGCCGCCAGGCTGCATCTCACCCCTTTATTCCACCAGCTCACATAAGGTCTGGTCCGATCCAACACTA
TCTAGCTGTAGGTTGTGAGCATTGTTGTACGGGTTATTATGGCCGAACGGGTATTTATGAAATGCTGAGTGTAACGCCGC
AGATTCAGCAAGCCATACTCAATAATGCCAGCCCTGTAAAACTGGTACAAATTGCCCAGAAGCAAGAACAAACAGCCTTA
CTCTGCTCAGGTTTAGCTTTAATCGAAAAAGGCATCACTACCCTTAGTGAAATTAATCGTGTTGTGGGCTTCGTAGCAGA
AACAGAGGTCACCTCTTGA

Protein sequence :
MAEFTVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFTCGRQVRVEYWPEAKIEQSLYLGSPTK
NNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQTIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQHHYRVR
LRIDGVLHEFTPPEAEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQIQQQTT
LEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNICSVEDPIEIPVNGINQTQVNSKIGLDF
SRILRAILRQDPDVIMVGEIRDNETASIAVNAAQTGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIAQRLVRR
LCLHCRQAASHPFIPPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQKQEQTAL
LCSGLALIEKGITTLSEINRVVGFVAETEVTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
gspE YP_854406.1 type II secretion protein GspE Not tested PAI I APEC-O1 Protein 2e-72 45
gspE CAE85233.1 GspE, hypothetical type II secretion protein Not tested PAI V 536 Protein 1e-72 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hofB YP_069247.1 hypothetical protein VFG0112 Protein 3e-84 48
hofB YP_069247.1 hypothetical protein VFG2426 Protein 9e-75 46
hofB YP_069247.1 hypothetical protein VFG2048 Protein 3e-74 46
hofB YP_069247.1 hypothetical protein VFG0182 Protein 2e-70 46
hofB YP_069247.1 hypothetical protein VFG0233 Protein 4e-76 46