|
Name : YPTB0566 (YPTB0566) Accession : YP_069108.1 Strain : Yersinia pseudotuberculosis IP 32953 Genome accession: NC_006155 Putative virulence/resistance : Resistance Product : heavy metal/multi-drug efflux protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0841 EC number : - Position : 666038 - 669124 bp Length : 3087 bp Strand : + Note : similar to Yersinia pestis YPO0421 multi-drug efflux protein (99.9% evalue=0); Vibrio cholerae VC1673 transporter, AcrB/D/F family (50.8% evalue=0) DNA sequence : ATGAAGCTGACTGATAATTTTATCAATAATAATACCCGTATCTGGCTAACGATTCTGTTGCTAGGTATTGGTGGCATTAT TGCCTATCTCAATATAGGCAGGCTGGAAGACCCGGCTTTTACCATCAAAACCGCGGTCGTTGTCACCCGCTATGATGGCG CATCGGCACAACAGGTTGAAGAAGAAGTCACGCTACCGTTGGAGAATGCTATTCAGGAACTCTCCTATGTGGATGACGTA ACCTCCATTTCCAGTGCCGGTTTATCGCAGATAACCATTAATATTCGTGCGCAATACGGCGCGAATGAGTTACCGCAAAT CTGGGATGAGCTGCGGCGTAAAATTAGCGATAACAGTGTTCGCCTACCACCAGGGGCCAGTGCCCCCATGGTCAACGATG ATTTTGGCGATGTTTACGGTTTCTTCTTCTCACTGACCGGTGACGGCTACAGTAATCAGGATCTGCGTAATTTTGCCGAG CAATTGCGGCGTGAATTAGTGTTGGTGCCCGGTGTGGGTAAAGTCGGCATCGTGGGTATTTTACCGGAAGAAGTTCAGGT AGAAATTTCCCGTGCGCAGATGACGGCCGCGGGTATTACACCGCAGCAGCTATCCGACTTGCTGAGTCGCCAAAACGTCG TGTCCGATGCAGGCCAGTTGCAGGTGGGCAGTGAGTCGATTCGCTTGCACCCGACTGGCGAATTCCAAAGCGTACAAGAG CTGGGGAATTTACTGGTCAGCCAACCCGGTAGCCCAAAAAGTGTCTATCTGCGCGATATTGCCACGGTAACCCAAGGCTT TGGTCATTCACCGACCAATATTTATCGCGCGAACGGTCAACCGGCATTGGCGTTAGGGATCTCGTTTGCTCCCAATGTTA ACGTGGTAAATGTTGGGAATGCGATTAAATCCCGTCTGGCGCAGCTTGAAGGTGAGCGCCCGTCCGGGATGCATATCAAT GTGTTCTACGATCAGTCTAAGGAAGTTGAAGGTGCGGTTAACGGCTTCATTCTTAACTTCCTGCTGGCACTGTTGATTGT TGTCGTTACCCTGCTGATCTTTATGGGGGTACGCAGCGGCGTGGTTATTGCCATCTCGCTGGCACTTAACGTGCTCGGAA CGTTGCTCATCATGTGGCTGTTTAACATCGAGCTACAGCGGGTATCGTTAGGGGCGCTGATCATTGCGCTGAGTATGCTG GTGGATAACGCCATCGTGGTGGTGGAAGGGGTGGTCGTTGGGCGTCAGCGCGGCGATAGCATTTCTACTGCTATCGGTAA TGTGGTGAAACGCTCGAAGATGCCGTTGCTGGGTGCGACCATTATTGCCATTTTGGCCTTTGCGCCTATCGGCCTGTCCA ATGATGCTACCGGCGAATATTGTAAGTCGCTATTCCAGGTGTTGCTCATCTCGTTAATGTTGAGCTGGATCACTGCGTTA ACGTTAACACCGGTGTTTGCCAAGTGGGCATTCCAGAACCAAAAACAGCCTGAAGCTGATGCGGATAAGCCGGTTAAACA ACCGTATGACGGCTGGTTATTCCGCTATTATCGGGTGGTGTTGAATAAATTACTGCAACACCGCAGTATTACATTAGTGC TCTTGGCCGCGTTATTAGTGGCGTCGGTTATCGGTTTTGGTCATGTTCGACAGAGCTTCTTCCCGCCTTCTAACACACCA ATCTTCTTTGTGGATATTTGGCTGCCTTATGGTACGGATATCAGCTATACCGAAGATATTGCAGCCAAAATTGAACAGCA TATCAAGCAGCAAAAAAATGTAGCGGATACCATGACAACCATAGGTCAGGGCGCAATGCGCTTTATGCTGACCTACAATG GTCAACGTCATTATCCTAACTATGCGCAGGTGATGGTCCGTACTGAGCAACTGGAGCAAATACCGGGCTTGATTGATGAA ATCGAGTCATATATGCATGACGAATATCCGCAGGTTGATGCGCAGATCAAACGCATCATGTTCGGGCCGTCAAACAACAG TTCTATTGAAGCTCGCTTTATTGGCCCCGATCCAGATGTGCTACGCACCTTGGCAGCCCAGGCGGAACAGGCGATTATCG CTGACCCAATGGCCGATGGTGCAAGGCATGACTGGCAGGATCGTAGCAAGATGATCCGGCCACAATTCTCCGATTATCTG GGCCGCGAGTTGGGGGTCGATAAACGCGAGGTGGATGGTACGTTGCGCATGAGTTTTGGTGGCTTGCCGGTTGGGTTATA CCGCGATGGTACCCGCCTGATACCTATTGTCCTACGCACACCGGACTCTGAGCGGCTCAATGCTGAGCGGTTGAACGATG TGATGGTCTGGAGCCAGGCGCGCCAAGCCTTTATCCCGATCGACAACGTGGTCACCAGTTTTGAAACCGAGTGGGAAGAT CCACTGATTATGCGTCTGGATCGTAAGCGGACACTGACGGTACAAACGGATCCAACCCATCAGGGCGGTGAGACCTCTTC CGAGTTGTTGCAACGGATCAAGCCGGGCGTTGAAGCCATTACCTTGCCACGGGGCTATGAACTGGAGTGGGGCGGCGATT ACGAAAGTACCAAAGAAGCACAGCGGGGTATTTTCATTAGCTTGCCGATCGCGTTTCTGCTTATGTTTGTTGTGACCGTG CTGATGTTTAGCTCGGTGCGTAATGCACTGGCTATTTGGCTGACGGTACCACTGGCATTAATTGGTGTGACCTTCGGCTT CCTACTGACGGGGATTCCGTTCGGCTTTATGGCCTTGCTGGGGTTATTAAGCCTGAGTGGGATGTTGATCCGTAACGGTA TTGTACTGGTCGAAGAGATTGGTCTACAGCGGCAAGAGAAACCGTTGCGTGAGGCGATTATCGATGCTTCCACCGCGCGT TTACGGCCTATCATGCTGACCGCATTTACCACCGTGTTGGGGCTGGCTCCGCTGCTGAGCGATGCCTTCTTCCAGAGTAT GGCGGTGGTGATTATGTTTGGCTTGGGCTTCGCGACAGTACTGACATTGCTGGTACTGCCAGTGATTTACAGCAGTATGA ATCCAGAGCCTAAAGAAAAGATCCACGATGAGCCAGTGAGTGAATAA Protein sequence : MKLTDNFINNNTRIWLTILLLGIGGIIAYLNIGRLEDPAFTIKTAVVVTRYDGASAQQVEEEVTLPLENAIQELSYVDDV TSISSAGLSQITINIRAQYGANELPQIWDELRRKISDNSVRLPPGASAPMVNDDFGDVYGFFFSLTGDGYSNQDLRNFAE QLRRELVLVPGVGKVGIVGILPEEVQVEISRAQMTAAGITPQQLSDLLSRQNVVSDAGQLQVGSESIRLHPTGEFQSVQE LGNLLVSQPGSPKSVYLRDIATVTQGFGHSPTNIYRANGQPALALGISFAPNVNVVNVGNAIKSRLAQLEGERPSGMHIN VFYDQSKEVEGAVNGFILNFLLALLIVVVTLLIFMGVRSGVVIAISLALNVLGTLLIMWLFNIELQRVSLGALIIALSML VDNAIVVVEGVVVGRQRGDSISTAIGNVVKRSKMPLLGATIIAILAFAPIGLSNDATGEYCKSLFQVLLISLMLSWITAL TLTPVFAKWAFQNQKQPEADADKPVKQPYDGWLFRYYRVVLNKLLQHRSITLVLLAALLVASVIGFGHVRQSFFPPSNTP IFFVDIWLPYGTDISYTEDIAAKIEQHIKQQKNVADTMTTIGQGAMRFMLTYNGQRHYPNYAQVMVRTEQLEQIPGLIDE IESYMHDEYPQVDAQIKRIMFGPSNNSSIEARFIGPDPDVLRTLAAQAEQAIIADPMADGARHDWQDRSKMIRPQFSDYL GRELGVDKREVDGTLRMSFGGLPVGLYRDGTRLIPIVLRTPDSERLNAERLNDVMVWSQARQAFIPIDNVVTSFETEWED PLIMRLDRKRTLTVQTDPTHQGGETSSELLQRIKPGVEAITLPRGYELEWGGDYESTKEAQRGIFISLPIAFLLMFVVTV LMFSSVRNALAIWLTVPLALIGVTFGFLLTGIPFGFMALLGLLSLSGMLIRNGIVLVEEIGLQRQEKPLREAIIDASTAR LRPIMLTAFTTVLGLAPLLSDAFFQSMAVVIMFGLGFATVLTLLVLPVIYSSMNPEPKEKIHDEPVSE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0395_A1355 | YP_001217299.1 | AcrB/AcrD/AcrF family transporter | Not tested | VPI-2 | Protein | 7e-167 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| YPTB0566 | YP_069108.1 | heavy metal/multi-drug efflux protein | BAC0428 | Protein | 0.0 | 52 |
| YPTB0566 | YP_069108.1 | heavy metal/multi-drug efflux protein | BAC0519 | Protein | 0.0 | 51 |
| YPTB0566 | YP_069108.1 | heavy metal/multi-drug efflux protein | BAC0526 | Protein | 0.0 | 48 |
| YPTB0566 | YP_069108.1 | heavy metal/multi-drug efflux protein | BAC0425 | Protein | 3e-167 | 41 |
