Gene Information

Name : YPTB3886 (YPTB3886)
Accession : YP_072362.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4636419 - 4637633 bp
Length : 1215 bp
Strand : -
Note : similar to Escherichia coli ECs4534 integrase (82.2% evalue=0); Escherichia coli Z5087 intL; integrase for prophage 933L and the LEE pathogenicity island (82.2% evalue=0)

DNA sequence : 
ATGCCACTAACGGACATTAAGGTGAAAACGGCTAAGCCGATAGATAAGGCTTACAAGCTAACTGACGGGGGCGGCATGTA
TCTGTTGGTTAAACCGAATGGCTCAAAATACTGGCGACTGAAGTACCGTTTTGTCGGCAAGGAAAAGATGCTATCGATCG
GCGTTTATCCGGATGTCTCTTTAGCTGATGCACGCCAAAAGAGAGACGAGGCGCGTAAAGTCTTGGCTGCAGGGGGCGAT
CCTGGTGAGGTGAAGAAGGCGGATAAGCTGGCGCAAAAACTCTCTTCTGAAAACACGTTTGAGGCTATCGCCCGCGAGTG
GCATAAGCAAAAGGCTGATCGTTGGTCTTTACGTTATCGCGATGAAATCATTGATACCTTCGAGAAGGACATATTCCCTT
ACCTTGGTCGACGCCCGATTGCTGAGATTAAGCCAATGGAGCTGCTCGAAACGCTCCGGCGCTTGGAGAAACGCGGTGCG
CTGGAGAAGATGCGTAAAGTACGCCAGCGTTGTGGTGAGGTATTTCGCTATGCCATTGTGACCGGGCGTGCGGAATACAA
CCCGGCCCCCGATCTGGCGACTGCCTTGGCAACGCCAAAGAAAACCCACTTTCCCTTCCTTACCGCAGAAGAACTTCCAT
ATTTCATCAGGGATCTGGCCGGGTACACAGGCAGTGTGATCACTAAAACGGCGACGCAAATCATCATGCAAACGGGGGTT
CGCACTCAGGAACTGCGTTTTGCACGTTGGGAAGATATCGACTTTGAGAAGCGTCTTTGGGAGATCCCTTCTGAAGTGAT
AAAGATGAAGCGGCCACATATCGTTCCGTTGTCGGAGCAGGTTGTGGAGCTGTTTCAGTCGCTGAAGCCGATTACCGGAA
TGTATCCGTTGGTATTTATTGGAAGAAATGACCGGGCAAAGCCGATTTCAAAGGAAAGCGTTAATCAGGTGATTGAGCTG
CTGGGTTATAAGGGAAGGCTGACAGGGCACGGTTTTCGCCACACGATGAGCACGATCTTGCATGAGCAGGGGTTCAACTC
GGCATGGATAGAGACACAGCTGGCTCATGTGGATAAGAATGCGATTCGCGGCACGTACAACCATGCGCATTACCTGGAGG
GAAGACGGGAGATGATGCAGTGGTATGGGGATAATCTTGAATCAATGTTGAATGGTGAAATGATACTACACGGATCATTT
AGCAAGAGTGCATAA

Protein sequence : 
MPLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVSLADARQKRDEARKVLAAGGD
PGEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYRDEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGA
LEKMRKVRQRCGEVFRYAIVTGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGV
RTQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFIGRNDRAKPISKESVNQVIEL
LGYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKNAIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSF
SKSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int CAC39282.1 integrase Not tested LPA Protein 7e-152 85
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-152 85
int AAD44730.1 Int Not tested SHI-2 Protein 8e-151 84
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 4e-150 84
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 4e-150 84
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 3e-150 84
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-150 83
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-150 83
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-150 83
int ACU09430.1 integrase Not tested LEE Protein 1e-150 83
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 7e-113 63
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 4e-115 61
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 8e-73 43
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 8e-73 43
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-72 43
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-72 43
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-72 43
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-72 43
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-72 43
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 5e-73 43
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 4e-69 43
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 4e-69 43
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 5e-70 42
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-72 42
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 6e-72 42
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 9e-72 42
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 7e-72 42
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-71 42
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-72 42
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-71 42
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 3e-72 42
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-72 42
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-72 42
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-61 41
int AAK00456.1 Int Not tested SHI-1 Protein 3e-63 41
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-64 41
int CAC81896.1 integrase Not tested LEE II Protein 6e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTB3886 YP_072362.1 integrase VFG0598 Protein 2e-150 84
YPTB3886 YP_072362.1 integrase VFG0783 Protein 8e-151 83
YPTB3886 YP_072362.1 integrase VFG0626 Protein 3e-73 43
YPTB3886 YP_072362.1 integrase VFG1693 Protein 7e-73 42
YPTB3886 YP_072362.1 integrase VFG1536 Protein 6e-65 41