Gene Information

Name : YPTB0311 (YPTB0311)
Accession : YP_068857.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : two-component sensor/regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0642
EC number : -
Position : 377880 - 380699 bp
Length : 2820 bp
Strand : -
Note : similar to Yersinia pestis YPO0256 two-component sensor/regulator (98.8% evalue=0); Salmonella typhi STY1728 ssrA, spiR; two-component sensor kinase (44.1% evalue=0)

DNA sequence :
ATGGGCAAAGCATCATCACTTGTCACTCGATTGACATTATTACTGGGCGTCACACTAACCGTTATTTGGTTAATATTAAT
CGCAACAACAGCATTCTTTTCATATGAAAATACACGTCAAATATTAATCAATGAGTTAACACATATGGCATCGATGCGGG
CAGACTTAAGTAATCACCAGTTTGAAGGAGCTGAACGTGATGCAGCCTCGTTAATAAGCCGACGAGAAAGCCTCCAGAGC
ACCTCACCGTTGCCTGAAATATCGATAAAACATTATGATAGCTGCTATATTCCTTTTAATCTGGACAGCTGTAATATTAA
CCAACATAAAAATGATCTGTGGATAATTCAAGCGTATGGCACCGCCGGACAAACTTATTATCTCGACAGTTTTATTATCA
AACAAAAAGAGGGGATTGTGTTATTTCCACCCCAAAAATCATCGAGTGATTACCTAAATCAACGGCGCAAAGATTTACTT
TTGCTCCCCAAATTCCCTACTCACAATAATATCTATTGGGGAGCCCCCACCTATACGCCTCAAGGTGGCTGGCATGTTTC
TGTCGCGGTGTGTGATAAAGTGGGCACCTTGGCTGGCTTCGCCTTAAAACTGAATGATCTCATCGCCTATAATCACCCTG
TCGAGCAAAGAGACATTAATTTATTGTTGGATAAGAATGGTGAATTATTACCTATTTCCCAGCAAGCAACATCATCAAAT
CAACTACATGAAATTCTTAACCAACTCAAAAACAGTAAATTACACGATGGCTGGCAGCAAACTCCCGACTATTTGGTATT
ACGCACCCAATTGAAAGGGCCGGGTTGGCAGCAATTAGTTATTTATCCACGAATAGGCTTTGCCTGGGAGGCACTGAAAC
CCGCCTTATATCAACTCCCTTTCGCTCTGGTTATTTTGCTGTTACTCACGTCAGTGCTGTCACTGCTGCTGCGATATTAT
CTGGCGATCCCTTTGTGGAATTTCATCAATATCATTGGCGCTACCGGGCCACAGGCAATGGAACCCCGACTTCCCATAAA
CCGAATAGATGAATTAGGGCATATTGCCCGCGCTTACAATAACTTACTGGATACGTTGAACGAACAATATGACACCTTAG
AAATGAAAGTGAAGGAGCGTACTCTGGCTCTGGCAAAAGCCAAACGAGCTGCTGAGCAGGCTAACCGCCGTAAAAGCGAC
CATCTGACCACGATAAGCCATGAAATCCGTACACCGCTCAACGGGGCGTTGGGGGCGGTTGAATTATTACAAAATACACC
ACTGGATGCTGGCCAAATGAGGTTAGCGGAAACGGCTCACCAATGTTCGTTGTCACTGCTCGCGATCATTAACAACCTGT
TAGATTTTTCACGTATTGAATCAGGGCAAATGACACTGTCGCTGGAGAAAACGGCCCTACTGCCTTTACTGGATCAGGCG
ATGTTAACCATTCATAGCCAGGCACTGAGTAAGTCATTAGCGCTGTCCACGTTTATCAGTGCCGATATCCCGCTGGAACT
TGAGCTGGATACACTGCGCTTAAGACAGATTCTGGTTAATTTATTAGGTAATGCCGTTAAATTCACACCACAGGGCCGTA
TTCAACTCAGGGTCAGGCGTCAAAACCAAACGCTTTGTTTTACCGTTGAGGACACCGGTTGTGGTATTGACGTGCAACAC
CAACAAACAATATTCCAACCTTTTATGCAGACCAGTGACCATGAACAAGGAACGGGTTTGGGGCTGGCTATCGCAGATAA
TCTGGCCAAAATGATGGGAGGGCACCTGACAGTATTCAGTGAACCGGGTCAAGGTAGCTGTTTTTCATTATGCCTCCCCT
TCAATGCAATCACCCCACCCATGCCTTTTCATGGCGAGCTATTCGCACCACAGCGCTTACACGCCCAATTATCAGCCTGG
GGCATGACCTGCCAGCCAGAATTAGCTAATCAGCCATCACGGTACTTTGTGGATAACGCATTGTGTTACTTGCCCGGCCG
GTTATACGCCAACCTGAAGCAATATCTACAAGGTGCTGAGACTGAGGTGCTAAAGAGCCTTCCGCTGCAACCTTGGCAAA
TGCACATTCTGCTGGTTGATGACTCCGAAACGAATCGCGATATTACCGGAATGATGTTGCAGCAACTGGGACATCAGGTC
ACGCTGGCAGACAGTGGCACAACCGCATTGGCGATTGGCCGCCAACACCGTTTCGATTTAGTGCTAATGGATATTCGAAT
GCCTGTCCTGGACGGGCTGGCCACCACAGCACGCTGGCGTCATGATCCGGCGAACATTGATAGCCACTGCATGATCACCG
CCCTGAGCGCCAATGCCAGCCCGGATGAGCAAATCAAAACCAGTCAGGCGGGGATGAACCACTACCTTTCCAAGCCTGTC
ACCCTCGGCCAATTGGCTGAAATGTTAGATCTGACCGCACAATTCCAACTTGAACGTGGGGTCGATCTATCGCCACAACT
CTCCGAGCCTCAGCCATTACTGGATCTCGCGGATAGCGCGTTGTCCCTGAAACTTTATCAATCACTGCAAGTATTAATTC
AACAGGCCAAAGACGCTATTGAGAACTTGCCCGTATTATCCCATACGCTTCACACCATAAAAGGCTGTGCCGGGCAAGCT
GGGCTAATTGAATTACAAGATGCGGTCATTCAATTAGAACACGCTCTCGATACTCATGAAACGCTGACACAGCAAGATAT
CATTCAACTTGATGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCC
AGTCCCTTATGGTTAAATAA

Protein sequence :
MGKASSLVTRLTLLLGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQS
TSPLPEISIKHYDSCYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYLDSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLL
LLPKFPTHNNIYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVEQRDINLLLDKNGELLPISQQATSSN
QLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRIGFAWEALKPALYQLPFALVILLLLTSVLSLLLRYY
LAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAKAKRAAEQANRRKSD
HLTTISHEIRTPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQA
MLTIHSQALSKSLALSTFISADIPLELELDTLRLRQILVNLLGNAVKFTPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQH
QQTIFQPFMQTSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFNAITPPMPFHGELFAPQRLHAQLSAW
GMTCQPELANQPSRYFVDNALCYLPGRLYANLKQYLQGAETEVLKSLPLQPWQMHILLVDDSETNRDITGMMLQQLGHQV
TLADSGTTALAIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDSHCMITALSANASPDEQIKTSQAGMNHYLSKPV
TLGQLAEMLDLTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQSLQVLIQQAKDAIENLPVLSHTLHTIKGCAGQA
GLIELQDAVIQLEHALDTHETLTQQDIIQLDEIIHVLLQPPTTCESTFIISQGQSLMVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 0.0 99
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 9e-142 47
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 6e-149 45
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 2e-149 45
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 1e-148 45
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 2e-149 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTB0311 YP_068857.1 two-component sensor/regulator VFG0493 Protein 5e-149 45