Gene Information

Name : tktA (YPTB3198)
Accession : YP_071699.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3761572 - 3763566 bp
Length : 1995 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCTCTCGTAAAGAGCTTGCCAACGCTATCCGCGCACTAAGCATGGATGCCGTGCAAAAAGCGAAGTCCGGCCATCC
CGGAGCCCCGATGGGTATGGCAGATATTGCCGAAGTCCTGTGGCGTGATTATCTGAACCATAATCCAACTAACCCACACT
GGGCTGATCGTGACCGTTTCGTCCTGTCAAATGGTCACGGCTCCATGTTGATTTATAGCCTGTTGCATCTCACAGGTTAT
GACCTGCCGATGGAAGAGCTAAAAAATTTCCGCCAACTGCACTCTAAAACGCCTGGCCACCCTGAATATGGTTATACCGC
TGGTGTAGAAACCACCACTGGGCCATTGGGGCAAGGCATTGCCAATGCTGTTGGTTTTGCTATCGCAGAACGCACGCTGG
GAGCGCAGTTTAACCGCCCAGGTCACGACATTGTTGATCACCATACCTACGCTTTTATGGGCGATGGTTGCATGATGGAA
GGTATCTCTCACGAGGTTTGCTCGCTGGCCGGTACGATGAAGCTGGGCAAACTGACGGCTTTCTATGATGACAACGGTAT
TTCTATCGATGGTCATGTTGAAGGCTGGTTCACTGATGACACGGCTGCCCGTTTCGAAGCCTACGGCTGGCATGTGGTAC
GTGGTGTTGATGGTCATAACGCGGACGCCATCAAAGCGGCTATCGAAGAAGCCCATCAGGTTACCGACAAGCCTTCATTG
TTGATGTGCAAAACGATTATCGGTTTTGGCTCACCAAACAAAGCTGGCACCCATGATTCCCATGGTGCGCCATTAGGTGA
AGCGGAAGTGGCAGCAACCCGTGAAGCATTAGGTTGGAAATACCCGGCATTTGAAATCCCACAAGATATCTATGCGGCAT
GGGATGCCAAAGAAGCGGGCAAAGCCAAAGAAGCGGCCTGGAACGAGAAGTTTGCTGCGTATGCCAAGGCTTATCCAGAA
CTGGCGGCTGAATTCAAACGTCGTGTCAGCGGTGAATTACCGGCTAACTGGGCCGTTGAATCCAAGAAATTCATCGAACA
ATTGCAAGCCAATCCAGCAAATATTGCCAGCCGCAAAGCCTCACAAAATGCGCTGGAAGCCTTCGGTAAAGTGTTACCTG
AGTTCCTGGGCGGTTCTGCTGATCTGGCACCGAGTAACCTGACTATCTGGTCTGGCTCTAAATCCTTGAGCGACGATCTG
GCTGGTAACTACATTCACTACGGTGTCCGTGAATTTGGTATGTCTGCCATCATGAACGGTATTGCCCTGCACGGCGGTTT
CATCCCTTACGGCGCAACCTTCCTGATGTTTGTGGAATATGCCCGTAATGCAGTGCGCATGGCGGCACTGATGAAAATCC
GTAGCGTGTTCGTTTATACCCATGACTCTATTGGTCTGGGCGAAGATGGCCCAACCCATCAGCCTGTTGAACAGATGGCC
AGCCTGCGTGTTACCCCGAATATGAGTACCTGGCGTCCTTGTGATCAGGTCGAATCTGCAGTGGCATGGCAGTATGCGCT
GGAACGTAAAGATGGCCCAAGCGCACTGATCTTCTCTCGACAGAATCTGGCACAGCAGCCACGTACTGCGGAGCAGCTAG
CCAATATCGCCAAAGGCGGGTATGTGCTGAAGGATTGTGCAGGCCAGCCTGAACTGATCCTGATTGCTACCGGCTCTGAA
GTGGAGTTAGCAGTTGCTGCGGCTGATCAACTGACGGCCACTGGCCGTAAAGTCCGCGTTGTCTCTATGCCATCAACTGA
TGCATTCGATAAACAAGATGCGGCTTACCGTGAGTCAGTATTGCCATCTGCGGTTAGCGCACGTGTTGCCGTAGAAGCGG
GTATTGCGGATTATTGGTACAAATACGTTGGCCTGAATGGCGCGGTTGTCGGTATGACCACGTTTGGTGAATCAGCGCCA
GCTGAATTGCTGTTCAAAGAGTTTGGTTTCACCGTGGAAAACGTGGTGGCGAAAGCTCAGGCGCTGCTGAAGTAA

Protein sequence :
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDYLNHNPTNPHWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPMEELKNFRQLHSKTPGHPEYGYTAGVETTTGPLGQGIANAVGFAIAERTLGAQFNRPGHDIVDHHTYAFMGDGCMME
GISHEVCSLAGTMKLGKLTAFYDDNGISIDGHVEGWFTDDTAARFEAYGWHVVRGVDGHNADAIKAAIEEAHQVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGEAEVAATREALGWKYPAFEIPQDIYAAWDAKEAGKAKEAAWNEKFAAYAKAYPE
LAAEFKRRVSGELPANWAVESKKFIEQLQANPANIASRKASQNALEAFGKVLPEFLGGSADLAPSNLTIWSGSKSLSDDL
AGNYIHYGVREFGMSAIMNGIALHGGFIPYGATFLMFVEYARNAVRMAALMKIRSVFVYTHDSIGLGEDGPTHQPVEQMA
SLRVTPNMSTWRPCDQVESAVAWQYALERKDGPSALIFSRQNLAQQPRTAEQLANIAKGGYVLKDCAGQPELILIATGSE
VELAVAAADQLTATGRKVRVVSMPSTDAFDKQDAAYRESVLPSAVSARVAVEAGIADYWYKYVGLNGAVVGMTTFGESAP
AELLFKEFGFTVENVVAKAQALLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 88
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 71